| Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and-independent mechanisms LI Grad, JJ Yerbury, BJ Turner, WC Guest, E Pokrishevsky, MA O’Neill, ... Proceedings of the National Academy of Sciences 111 (9), 3620-3625, 2014 | 457 | 2014 |
| ANS binding reveals common features of cytotoxic amyloid species B Bolognesi, JR Kumita, TP Barros, EK Esbjorner, LM Luheshi, ... ACS chemical biology 5 (8), 735-740, 2010 | 416 | 2010 |
| A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis JH Jung, AD Barbosa, S Hutin, JR Kumita, M Gao, D Derwort, CS Silva, ... Nature 585 (7824), 256-260, 2020 | 409 | 2020 |
| Photo-control of helix content in a short peptide JR Kumita, OS Smart, GA Woolley Proceedings of the National Academy of Sciences 97 (8), 3803-3808, 2000 | 390 | 2000 |
| The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures JJ Yerbury, S Poon, S Meehan, B Thompson, JR Kumita, CM Dobson, ... The FASEB Journal 21 (10), 2312-2322, 2007 | 365 | 2007 |
| α-Helix formation in a photoswitchable peptide tracked from picoseconds to microseconds by time-resolved IR spectroscopy J Bredenbeck, J Helbing, JR Kumita, GA Woolley, P Hamm Proceedings of the National Academy of Sciences 102 (7), 2379-2384, 2005 | 243 | 2005 |
| Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ... Nature chemistry 10 (6), 673-683, 2018 | 222 | 2018 |
| Protein amyloids develop an intrinsic fluorescence signature during aggregation FTS Chan, GSK Schierle, JR Kumita, CW Bertoncini, CM Dobson, ... Analyst 138 (7), 2156-2162, 2013 | 221 | 2013 |
| Using an azobenzene cross-linker to either increase or decrease peptide helix content upon trans-to-cis photoisomerization DG Flint, JR Kumita, OS Smart, GA Woolley Chemistry & biology 9 (3), 391-397, 2002 | 219 | 2002 |
| Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, ... Proceedings of the National Academy of Sciences 114 (2), E200-E208, 2017 | 213 | 2017 |
| Nature and significance of the interactions between amyloid fibrils and biological polyelectrolytes M Calamai, JR Kumita, J Mifsud, C Parrini, M Ramazzotti, G Ramponi, ... Biochemistry 45 (42), 12806-12815, 2006 | 154 | 2006 |
| Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates T Scheidt, U Łapińska, JR Kumita, DR Whiten, D Klenerman, MR Wilson, ... Science Advances 5 (4), eaau3112, 2019 | 142 | 2019 |
| Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ... Nature communications 10 (1), 225, 2019 | 138 | 2019 |
| Defining α-synuclein species responsible for Parkinson’s disease phenotypes in mice JM Froula, M Castellana-Cruz, NM Anabtawi, JD Camino, SW Chen, ... Journal of Biological Chemistry 294 (27), 10392-10406, 2019 | 135 | 2019 |
| Normal and aberrant biological self-assembly: insights from studies of human lysozyme and its amyloidogenic variants M Dumoulin, JR Kumita, CM Dobson Accounts of chemical research 39 (9), 603-610, 2006 | 129 | 2006 |
| A FRET sensor for non‐invasive imaging of amyloid formation in vivo GS Kaminski Schierle, CW Bertoncini, FTS Chan, AT van der Goot, ... ChemPhysChem 12 (3), 673-680, 2011 | 127 | 2011 |
| The non-core regions of human lysozyme amyloid fibrils influence cytotoxicity MF Mossuto, A Dhulesia, G Devlin, E Frare, JR Kumita, PP de Laureto, ... Journal of molecular biology 402 (5), 783-796, 2010 | 125 | 2010 |
| Molecular determinants of the aggregation behavior of α‐and β‐synuclein RC Rivers, JR Kumita, GG Tartaglia, MM Dedmon, A Pawar, ... Protein Science 17 (5), 887-898, 2008 | 122 | 2008 |
| A water-soluble azobenzene cross-linker for photocontrol of peptide conformation Z Zhang, DC Burns, JR Kumita, OS Smart, GA Woolley Bioconjugate chemistry 14 (4), 824-829, 2003 | 122 | 2003 |
| Reversible photocontrol of DNA binding by a designed GCN4-bZIP protein GA Woolley, ASI Jaikaran, M Berezovski, JP Calarco, SN Krylov, ... Biochemistry 45 (19), 6075-6084, 2006 | 118 | 2006 |
