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Melissa R Junttila
Melissa R Junttila
ORIC Pharmaceuticals
在 oricpharma.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Influence of tumour micro-environment heterogeneity on therapeutic response
MR Junttila, FJ De Sauvage
Nature 501 (7467), 346-354, 2013
27472013
Phosphatase‐mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
MR Junttila, SP Li, J Westermarck
The FASEB Journal 22 (4), 954-965, 2008
10082008
CIP2A inhibits PP2A in human malignancies
MR Junttila, P Puustinen, M Niemelä, R Ahola, H Arnold, T Böttzauw, ...
Cell 130 (1), 51-62, 2007
7492007
Single-Cell RNA Sequencing Reveals Stromal Evolution into LRRC15+ Myofibroblasts as a Determinant of Patient Response to Cancer Immunotherapy
CX Dominguez, S Müller, S Keerthivasan, H Koeppen, J Hung, S Gierke, ...
Cancer discovery 10 (2), 232-253, 2020
5652020
Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors
DO Croci, JP Cerliani, T Dalotto-Moreno, SP Méndez-Huergo, ...
Cell 156 (4), 744-758, 2014
5482014
Randomized phase Ib/II study of gemcitabine plus placebo or vismodegib, a hedgehog pathway inhibitor, in patients with metastatic pancreatic cancer
DVT Catenacci, MR Junttila, T Karrison, N Bahary, MN Horiba, SR Nattam, ...
Journal of Clinical Oncology 33 (36), 4284-4292, 2015
5192015
Distinct thresholds govern Myc's biological output in vivo
DJ Murphy, MR Junttila, L Pouyet, A Karnezis, K Shchors, DA Bui, ...
Cancer cell 14 (6), 447-457, 2008
5092008
p53—a Jack of all trades but master of none
MR Junttila, GI Evan
Nature reviews cancer 9 (11), 821-829, 2009
5072009
Translational value of mouse models in oncology drug development
SE Gould, MR Junttila, FJ de Sauvage
Nature medicine 21 (5), 431-439, 2015
3192015
Selective activation of p53-mediated tumour suppression in high-grade tumours
MR Junttila, AN Karnezis, D Garcia, F Madriles, RM Kortlever, F Rostker, ...
Nature 468 (7323), 567-571, 2010
2742010
MYC-dependent regulation and prognostic role of CIP2A in gastric cancer
A Khanna, C Böckelman, A Hemmes, MR Junttila, JP Wiksten, M Lundin, ...
JNCI: Journal of the National Cancer Institute 101 (11), 793-805, 2009
2682009
Mechanisms of MYC stabilization in human malignancies
MR Junttila, J Westermarck
Cell cycle 7 (5), 592-596, 2008
2242008
Single‐step Strep‐tag® purification for the isolation and identification of protein complexes from mammalian cells
MR Junttila, S Saarinen, T Schmidt, J Kast, J Westermarck
Proteomics 5 (5), 1199-1203, 2005
1942005
p38α and p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells
MR Junttila, R Ala-Aho, T Jokilehto, J Peltonen, M Kallajoki, R Grenman, ...
Oncogene 26 (36), 5267-5279, 2007
1772007
Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer
MR Junttila, W Mao, X Wang, BE Wang, T Pham, J Flygare, SF Yu, S Yee, ...
Science translational medicine 7 (314), 314ra186-314ra186, 2015
1682015
Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells
TT Junttila, J Li, J Johnston, M Hristopoulos, R Clark, D Ellerman, ...
Cancer research 74 (19), 5561-5571, 2014
1632014
Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1
A Laine, H Sihto, C Come, MT Rosenfeldt, A Zwolinska, M Niemelä, ...
Cancer discovery 3 (2), 182-197, 2013
1572013
A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types
MC Wagle, D Kirouac, C Klijn, B Liu, S Mahajan, M Junttila, J Moffat, ...
NPJ precision oncology 2 (1), 7, 2018
1452018
CD3 bispecific antibody–induced cytokine release is dispensable for cytotoxic T cell activity
J Li, R Piskol, R Ybarra, YJJ Chen, J Li, D Slaga, M Hristopoulos, R Clark, ...
Science translational medicine 11 (508), eaax8861, 2019
1422019
p38 Mitogen-activated protein kinase pathway suppresses cell survival by inducing dephosphorylation of mitogen-activated protein/extracellular signal-regulated kinase kinase1, 2
SP Li, MR Junttila, J Han, VM Kähäri, J Westermarck
Cancer research 63 (13), 3473-3477, 2003
1292003
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