Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine JA Hackett, R Sengupta, JJ Zylicz, K Murakami, C Lee, TA Down, ... Science 339 (6118), 448-452, 2013 | 909 | 2013 |
A unique gene regulatory network resets the human germline epigenome for development WWC Tang, S Dietmann, N Irie, HG Leitch, VI Floros, CR Bradshaw, ... Cell 161 (6), 1453-1467, 2015 | 685 | 2015 |
Regulatory principles of pluripotency: from the ground state up JA Hackett, MA Surani Cell stem cell 15 (4), 416-430, 2014 | 425 | 2014 |
DNA methylation dynamics during the mammalian life cycle JA Hackett, MA Surani Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013 | 367 | 2013 |
Dynamic heterogeneity and DNA methylation in embryonic stem cells ZS Singer, J Yong, J Tischler, JA Hackett, A Altinok, MA Surani, L Cai, ... Molecular cell 55 (2), 319-331, 2014 | 299 | 2014 |
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ... The Lancet 400 (10349), 359-368, 2022 | 227 | 2022 |
Parallel mechanisms of epigenetic reprogramming in the germline JA Hackett, JJ Zylicz, MA Surani Trends in Genetics 28 (4), 164-174, 2012 | 208 | 2012 |
Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation N Grabole, J Tischler, JA Hackett, S Kim, F Tang, HG Leitch, ... EMBO reports 14 (7), 629-637, 2013 | 175 | 2013 |
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline JA Hackett, JP Reddington, CE Nestor, DS Dunican, MR Branco, ... Development 139 (19), 3623-3632, 2012 | 173 | 2012 |
PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos S Kim, U Günesdogan, JJ Zylicz, JA Hackett, D Cougot, S Bao, C Lee, ... Molecular cell 56 (4), 564-579, 2014 | 151 | 2014 |
Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency JA Hackett, S Dietmann, K Murakami, TA Down, HG Leitch, MA Surani Stem cell reports 1 (6), 518-531, 2013 | 151 | 2013 |
Identification of nuclear and cytoplasmic mRNA targets for the shuttling protein SF2/ASF JR Sanford, P Coutinho, JA Hackett, X Wang, W Ranahan, JF Caceres PloS one 3 (10), e3369, 2008 | 142 | 2008 |
Chromatin dynamics and the role of G9a in gene regulation and enhancer silencing during early mouse development JJ Zylicz, S Dietmann, U Günesdogan, JA Hackett, D Cougot, C Lee, ... elife 4, e09571, 2015 | 117 | 2015 |
Beyond DNA: programming and inheritance of parental methylomes JA Hackett, MA Surani Cell 153 (4), 737-739, 2013 | 99 | 2013 |
xDnmt1 regulates transcriptional silencing in pre-MBT Xenopusembryos independently of its catalytic function DS Dunican, A Ruzov, JA Hackett, RR Meehan Oxford University Press for The Company of Biologists Limited 135 (7), 1295-1302, 2008 | 96 | 2008 |
Stella modulates transcriptional and endogenous retrovirus programs during maternal-to-zygotic transition Y Huang, JK Kim, DV Do, C Lee, CA Penfold, JJ Zylicz, JC Marioni, ... Elife 6, e22345, 2017 | 93 | 2017 |
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome JP Thomson, H Lempiäinen, JA Hackett, CE Nestor, A Müller, F Bolognani, ... Genome biology 13, 1-17, 2012 | 91 | 2012 |
Cell surface mechanics gate embryonic stem cell differentiation M Bergert, S Lembo, S Sharma, L Russo, D Milovanović, KH Gretarsson, ... Cell Stem Cell 28 (2), 209-216. e4, 2021 | 86 | 2021 |
Tracing the transitions from pluripotency to germ cell fate with CRISPR screening JA Hackett, Y Huang, U Günesdogan, KA Gretarsson, T Kobayashi, ... Nature communications 9 (1), 4292, 2018 | 73 | 2018 |
The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development A Ruzov, E Savitskaya, JA Hackett, JP Reddington, A Prokhortchouk, ... Oxford University Press for The Company of Biologists Limited 136 (5), 729-738, 2009 | 73 | 2009 |