Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design EO Saphire, PWHI Parren, R Pantophlet, MB Zwick, GM Morris, PM Rudd, ... science 293 (5532), 1155-1159, 2001 | 1118 | 2001 |
The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of α1→ 2 mannose residues on the outer face of gp120 CN Scanlan, R Pantophlet, MR Wormald, E Ollmann Saphire, R Stanfield, ... Journal of virology 76 (14), 7306-7321, 2002 | 864 | 2002 |
GP120: target for neutralizing HIV-1 antibodies R Pantophlet, DR Burton Annu. Rev. Immunol. 24, 739-769, 2006 | 611 | 2006 |
Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120 R Pantophlet, E Ollmann Saphire, P Poignard, PWHI Parren, IA Wilson, ... Journal of virology 77 (1), 642-658, 2003 | 315 | 2003 |
Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors AK Dhillon, H Donners, R Pantophlet, WE Johnson, JM Decker, GM Shaw, ... Journal of virology 81 (12), 6548-6562, 2007 | 245 | 2007 |
Differential Roles of CD14 and Toll-like Receptors 4and 2 in Murine Acinetobacter Pneumonia S Knapp, CW Wieland, S Florquin, R Pantophlet, L Dijkshoorn, ... American journal of respiratory and critical care medicine 173 (1), 122-129, 2006 | 240 | 2006 |
Hyperglycosylated mutants of human immunodeficiency virus (HIV) type 1 monomeric gp120 as novel antigens for HIV vaccine design R Pantophlet, IA Wilson, DR Burton Journal of virology 77 (10), 5889-5901, 2003 | 181 | 2003 |
A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to … RD Astronomo, HK Lee, CN Scanlan, R Pantophlet, CY Huang, IA Wilson, ... Journal of virology 82 (13), 6359-6368, 2008 | 149 | 2008 |
Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds RD Astronomo, E Kaltgrad, AK Udit, SK Wang, KJ Doores, CY Huang, ... Chemistry & biology 17 (4), 357-370, 2010 | 141 | 2010 |
Comparing antigenicity and immunogenicity of engineered gp120 S Selvarajah, B Puffer, R Pantophlet, M Law, RW Doms, DR Burton Journal of virology 79 (19), 12148-12163, 2005 | 120 | 2005 |
A Dominant Role for CD8+-T-Lymphocyte Selection in Simian Immunodeficiency Virus Sequence Variation DH O'Connor, AB McDermott, KC Krebs, EJ Dodds, JE Miller, ... Journal of virology 78 (24), 14012-14022, 2004 | 114 | 2004 |
Structure of antibody F425-B4e8 in complex with a V3 peptide reveals a new binding mode for HIV-1 neutralization CH Bell, R Pantophlet, A Schiefner, LA Cavacini, RL Stanfield, DR Burton, ... Journal of molecular biology 375 (4), 969-978, 2008 | 101 | 2008 |
Reduced magnitude and durability of humoral immune responses to COVID-19 mRNA vaccines among older adults MA Brockman, F Mwimanzi, HR Lapointe, Y Sang, O Agafitei, PK Cheung, ... The Journal of Infectious Diseases 225 (7), 1129-1140, 2022 | 91 | 2022 |
Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions AC Biorn, S Cocklin, N Madani, Z Si, T Ivanovic, J Samanen, DI Van Ryk, ... Biochemistry 43 (7), 1928-1938, 2004 | 87 | 2004 |
Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12 R Pantophlet, IA Wilson, DR Burton Protein Engineering Design and Selection 17 (10), 749-758, 2004 | 82 | 2004 |
Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis R Pantophlet, RO Aguilar-Sino, T Wrin, LA Cavacini, DR Burton Virology 364 (2), 441-453, 2007 | 81 | 2007 |
Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy ZL Brumme, F Mwimanzi, HR Lapointe, PK Cheung, Y Sang, MC Duncan, ... npj Vaccines 7 (1), 28, 2022 | 77 | 2022 |
Structure of a high-affinity “mimotope” peptide bound to HIV-1-neutralizing antibody b12 explains its inability to elicit gp120 cross-reactive antibodies EO Saphire, M Montero, A Menendez, NE van Houten, MB Irving, ... Journal of molecular biology 369 (3), 696-709, 2007 | 76 | 2007 |
Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site KB Alexandre, ES Gray, R Pantophlet, PL Moore, JB McMahon, ... Journal of virology 85 (17), 9039-9050, 2011 | 75 | 2011 |
The carbohydrate epitope of the neutralizing anti-HIV-1 antibody 2G12 CN Scanlan, R Pantophlet, MR Wormald, EO Saphire, D Calarese, ... Glycobiology and Medicine, 205-218, 2003 | 72 | 2003 |