Human aquaporins: regulators of transcellular water flow RE Day, P Kitchen, DS Owen, C Bland, L Marshall, AC Conner, RM Bill, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (5), 1492-1506, 2014 | 378 | 2014 |
Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema P Kitchen, MM Salman, AM Halsey, C Clarke-Bland, JA MacDonald, ... Cell 181 (4), 784-799. e19, 2020 | 376 | 2020 |
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ... British Journal of Pharmacology 178, S157-S245, 2021 | 245 | 2021 |
Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis MM Salman, P Kitchen, A Halsey, MX Wang, S Tornroth-Horsefield, ... Brain, 2021 | 166 | 2021 |
Beyond water homeostasis: diverse functional roles of mammalian aquaporins P Kitchen, RE Day, MM Salman, MT Conner, RM Bill, AC Conner Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (12), 2410-2421, 2015 | 157 | 2015 |
Inhibitors of Mammalian Aquaporin Water Channels M Abir-Awan, P Kitchen, MM Salman, MT Conner, AC Conner, RM Bill International journal of molecular sciences 20 (7), 1589, 2019 | 127 | 2019 |
Identification and molecular mechanisms of the rapid tonicity-induced relocalization of the aquaporin 4 channel P Kitchen, RE Day, LHJ Taylor, MM Salman, RM Bill, MT Conner, ... Journal of Biological Chemistry 290 (27), 16873-16881, 2015 | 107 | 2015 |
Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases MM Salman, Z Al-Obaidi, P Kitchen, A Loreto, RM Bill, R Wade-Martins International Journal of Molecular Sciences 22 (9), 4688, 2021 | 104 | 2021 |
Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)‐and … MM Salman, P Kitchen, MN Woodroofe, JE Brown, RM Bill, AC Conner, ... European Journal of Neuroscience 46 (9), 2542-2547, 2017 | 97 | 2017 |
Recent breakthroughs and future directions in drugging aquaporins MM Salman, P Kitchen, AJ Yool, RM Bill Trends in pharmacological sciences 43 (1), 30-42, 2022 | 82 | 2022 |
HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development S Gauvrit, A Villasenor, B Strilic, P Kitchen, MM Collins, R Marín-Juez, ... Nature communications 9 (1), 1-14, 2018 | 78 | 2018 |
Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease K Wagner, L Unger, MM Salman, P Kitchen, RM Bill, AJ Yool International Journal of Molecular Sciences 23 (3), 1388, 2022 | 75 | 2022 |
Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis MM Salman, P Kitchen, JJ Iliff, RM Bill Nature Reviews Neuroscience 22 (10), 650-651, 2021 | 75 | 2021 |
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels SPH Alexander, AA Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ... British Journal of Pharmacology 180, S145-S222, 2023 | 67 | 2023 |
Plasma membrane abundance of human aquaporin 5 is dynamically regulated by multiple pathways P Kitchen, F Öberg, J Sjöhamn, K Hedfalk, RM Bill, AC Conner, ... PloS one 10 (11), e0143027, 2015 | 66 | 2015 |
Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy MM Salman, MA Sheilabi, D Bhattacharyya, P Kitchen, AC Conner, ... European Journal of Neuroscience 46 (5), 2121-2132, 2017 | 64 | 2017 |
Molecular mechanisms governing aquaporin relocalisation A Markou, L Unger, M Abir-Awan, A Saadallah, A Halsey, Z Balklava, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1864 (4), 183853, 2022 | 61 | 2022 |
Transcriptome analysis of gene expression provides new insights into the effect of mild therapeutic hypothermia on primary human cortical astrocytes cultured under hypoxia MM Salman, P Kitchen, MN Woodroofe, RM Bill, AC Conner, PR Heath, ... Frontiers in cellular neuroscience 11, 386, 2017 | 61 | 2017 |
Water channel pore size determines exclusion properties but not solute selectivity P Kitchen, MM Salman, SU Pickel, J Jennings, S Törnroth-Horsefield, ... Scientific Reports 9 (1), 20369, 2019 | 52 | 2019 |
CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism J Lertsuwan, K Lertsuwan, A Sawasdichai, N Tasnawijitwong, K Lee, ... Cancers 10 (9), 283, 2018 | 46 | 2018 |