Bidirectional signaling between the cytoskeleton and integrins SM Schoenwaelder, K Burridge Current opinion in cell biology 11 (2), 274-286, 1999 | 1003 | 1999 |
PI 3-kinase p110β: a new target for antithrombotic therapy SP Jackson, SM Schoenwaelder, I Goncalves, WS Nesbitt, CL Yap, ... Nature medicine 11 (5), 507-514, 2005 | 731 | 2005 |
Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms SP Jackson, R Darbousset, SM Schoenwaelder Blood, The Journal of the American Society of Hematology 133 (9), 906-918, 2019 | 543 | 2019 |
Rap1b is required for normal platelet function and hemostasis in mice M Chrzanowska-Wodnicka, SS Smyth, SM Schoenwaelder, TH Fischer, ... The Journal of clinical investigation 115 (3), 680-687, 2005 | 370 | 2005 |
Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function SM Schoenwaelder, Y Yuan, EC Josefsson, MJ White, Y Yao, KD Mason, ... Blood 114 (3), 663-666, 2009 | 355 | 2009 |
Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets SM Schoenwaelder, KE Jarman, EE Gardiner, M Hua, J Qiao, MJ White, ... Blood, The Journal of the American Society of Hematology 118 (6), 1663-1674, 2011 | 340 | 2011 |
Antiplatelet therapy: in search of the'magic bullet' SP Jackson, SM Schoenwaelder Nature Reviews Drug Discovery 2 (10), 775-789, 2003 | 276 | 2003 |
Reconstituted high-density lipoprotein attenuates platelet function in individuals with type 2 diabetes mellitus by promoting cholesterol efflux AC Calkin, BG Drew, A Ono, SJ Duffy, MV Gordon, SM Schoenwaelder, ... Circulation 120 (21), 2095-2104, 2009 | 252 | 2009 |
Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling ID Lawrenson, SH Wimmer-Kleikamp, P Lock, SM Schoenwaelder, ... Journal of cell science 115 (5), 1059-1072, 2002 | 225 | 2002 |
Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain P Cooray, Y Yuan, SM Schoenwaelder, CA Mitchell, HH Salem, ... Biochemical Journal 318 (1), 41-47, 1996 | 224 | 1996 |
Procoagulant platelets: are they necrotic? SP Jackson, SM Schoenwaelder Blood, The Journal of the American Society of Hematology 116 (12), 2011-2018, 2010 | 199 | 2010 |
The protein tyrosine phosphatase Shp-2 regulates RhoA activity SM Schoenwaelder, LA Petch, D Williamson, R Shen, GS Feng, ... Current Biology 10 (23), 1523-1526, 2000 | 193 | 2000 |
Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRγ deficiency P Mangin, CL Yap, C Nonne, SA Sturgeon, I Goncalves, Y Yuan, ... Blood 107 (11), 4346-4353, 2006 | 190 | 2006 |
Calpain cleavage of focal adhesion proteins regulates the cytoskeletal attachment of integrin αIIbβ3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin clots SM Schoenwaelder, Y Yuan, P Cooray, HH Salem, SP Jackson Journal of Biological Chemistry 272 (3), 1694-1702, 1997 | 175 | 1997 |
The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi M Ghasemzadeh, ZS Kaplan, I Alwis, SM Schoenwaelder, KJ Ashworth, ... Blood, The Journal of the American Society of Hematology 121 (22), 4555-4566, 2013 | 158 | 2013 |
Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth A Ono, E Westein, S Hsiao, WS Nesbitt, JR Hamilton, SM Schoenwaelder, ... Blood, The Journal of the American Society of Hematology 112 (1), 90-99, 2008 | 153 | 2008 |
Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and … SP Jackson, SM Schoenwaelder, Y Yuan, I Rabinowitz, HH Salem, ... Journal of Biological Chemistry 269 (43), 27093-27099, 1994 | 148 | 1994 |
Non-redundant roles of phosphoinositide 3-kinase isoforms α and β in glycoprotein VI-induced platelet signaling and thrombus formation K Gilio, ICA Munnix, P Mangin, JMEM Cosemans, MAH Feijge, ... Journal of Biological Chemistry 284 (49), 33750-33762, 2009 | 145 | 2009 |
Evidence for a calpeptin-sensitive protein-tyrosine phosphatase upstream of the small GTPase Rho: a novel role for the calpain inhibitor calpeptin in the inhibition of protein … SM Schoenwaelder, K Burridge Journal of Biological Chemistry 274 (20), 14359-14367, 1999 | 142 | 1999 |
Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling L Luo, AA Wall, JC Yeo, ND Condon, SJ Norwood, S Schoenwaelder, ... Nature communications 5 (1), 4407, 2014 | 126 | 2014 |