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Brian Tanaka
Brian Tanaka
Arvinas
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年份
Restoration of brain circulation and cellular functions hours post-mortem
Z Vrselja, SG Daniele, J Silbereis, F Talpo, YM Morozov, AMM Sousa, ...
Nature 568 (7752), 336-343, 2019
2632019
A gain-of-function mutation in Nav1. 6 in a case of trigeminal neuralgia
BS Tanaka, P Zhao, FB Dib-Hajj, V Morisset, S Tate, SG Waxman, ...
Molecular medicine 22, 338-348, 2016
1272016
Regulation of thalamic and cortical network synchrony by Scn8a
CD Makinson, BS Tanaka, JM Sorokin, JC Wong, CA Christian, AL Goldin, ...
Neuron 93 (5), 1165-1179. e6, 2017
1112017
Resilience to pain: a peripheral component identified using induced pluripotent stem cells and dynamic clamp
MA Mis, Y Yang, BS Tanaka, C Gomis-Perez, S Liu, F Dib-Hajj, T Adi, ...
Journal of Neuroscience 39 (3), 382-392, 2019
822019
Shaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anesthetics
MI Lioudyno, AM Birch, BS Tanaka, Y Sokolov, AL Goldin, KG Chandy, ...
Journal of Neuroscience 33 (41), 16310-16322, 2013
672013
Building sensory axons: Delivery and distribution of NaV1.7 channels and effects of inflammatory mediators
EJ Akin, GP Higerd-Rusli, MA Mis, BS Tanaka, T Adi, S Liu, FB Dib-Hajj, ...
Science Advances 5 (10), eaax4755, 2019
552019
Role of the hippocampus in Nav1. 6 (Scn8a) mediated seizure resistance
CD Makinson, BS Tanaka, T Lamar, AL Goldin, A Escayg
Neurobiology of disease 68, 16-25, 2014
542014
The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant
N Coleman, HM Nguyen, Z Cao, BM Brown, DP Jenkins, D Zolkowska, ...
Neurotherapeutics 12 (1), 234-249, 2015
432015
NaV1.6 regulates excitability of mechanosensitive sensory neurons
MR Israel, BS Tanaka, J Castro, P Thongyoo, SD Robinson, P Zhao, ...
The Journal of Physiology 597 (14), 3751-3768, 2019
382019
Differential effect of lacosamide on Nav1.7 variants from responsive and non-responsive patients with small fibre neuropathy
JIR Labau, M Estacion, BS Tanaka, BTA de Greef, JGJ Hoeijmakers, ...
Brain 143 (3), 771-782, 2020
372020
Dexpramipexole blocks Nav1. 8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models
M Urru, M Muzzi, E Coppi, G Ranieri, D Buonvicino, E Camaioni, ...
Pain 161 (4), 831-841, 2020
302020
Gain-of-function mutation of a voltage-gated sodium channel NaV1. 7 associated with peripheral pain and impaired limb development
BS Tanaka, PT Nguyen, EY Zhou, Y Yang, V Yarov-Yarovoy, SD Dib-Hajj, ...
Journal of Biological Chemistry 292 (22), 9262-9272, 2017
242017
Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation
J Huang, MA Mis, B Tanaka, T Adi, M Estacion, S Liu, S Walker, ...
Scientific reports 8 (1), 1811, 2018
192018
KCNQ variants and pain modulation: a missense variant in Kv7.3 contributes to pain resilience
JH Yuan, M Estacion, MA Mis, BS Tanaka, BR Schulman, L Chen, S Liu, ...
Brain Communications 3 (3), fcab212, 2021
182021
Lacosamide Inhibition of NaV1.7 Channels Depends on its Interaction With the Voltage Sensor Domain and the Channel Pore
JIR Labau, M Alsaloum, M Estacion, B Tanaka, FB Dib-Hajj, G Lauria, ...
Frontiers in Pharmacology 12, 791740, 2021
62021
Pharmacological activity and NMR solution structure of the leech peptide HSTX-I
KL McMahon, B Tay, JR Deuis, BS Tanaka, S Peigneur, AH Jin, J Tytgat, ...
Biochemical pharmacology 181, 114082, 2020
52020
Alternative polyadenylation signals in the 3′ non-coding region of a voltage-gated potassium channel gene are major determinants of mRNA isoform expression
GM Jang, BS Tanaka, GA Gutman, AL Goldin, BL Semler
Gene 408 (1-2), 133-145, 2008
32008
REDUCED EXCITABILITY OF NEURONAL CIRCUITS IN THE HIPPOCAMPUS OF SCN8A MUTANT MICE
BS Tanaka, AL Goldin
EPILEPSIA 50, 332-332, 2009
2009
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