[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations RB Pearson, BE Kemp Methods in enzymology 200, 62-81, 1991 | 1301 | 1991 |
Protein kinase recognition sequence motifs BE Kemp, RB Pearson Trends in biochemical sciences 15 (9), 342-346, 1990 | 1289 | 1990 |
Rapamycin suppresses 5′ TOP mRNA translation through inhibition of p70s6k HBJ Jefferies, S Fumagalli, PB Dennis, C Reinhard, RB Pearson, ... The EMBO journal, 1997 | 1203 | 1997 |
Mutation of the PIK3CA gene in ovarian and breast cancer IG Campbell, SE Russell, DYH Choong, KG Montgomery, ML Ciavarella, ... Cancer research 64 (21), 7678-7681, 2004 | 1144 | 2004 |
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase. HC Cheng, BE Kemp, RB Pearson, AJ Smith, L Misconi, SM Van Patten, ... Journal of Biological Chemistry 261 (3), 989-992, 1986 | 653 | 1986 |
The Akt kinase signals directly to endothelial nitric oxide synthase BJ Michell, JE Griffiths, KI Mitchelhill, I Rodriguez-Crespo, T Tiganis, ... Current biology 9 (15), 845-848, 1999 | 614 | 1999 |
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53 MJ Bywater, G Poortinga, E Sanij, N Hein, A Peck, C Cullinane, M Wall, ... Cancer cell 22 (1), 51-65, 2012 | 577 | 2012 |
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar … KM Hannan, Y Brandenburger, A Jenkins, K Sharkey, A Cavanaugh, ... Molecular and cellular biology, 2003 | 576 | 2003 |
The principal target of rapamycin‐induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. RB Pearson, PB Dennis, JW Han, NA Williamson, SC Kozma, ... The EMBO journal 14 (21), 5279-5287, 1995 | 549 | 1995 |
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function K Jastrzebski, KM Hannan, EB Tchoubrieva, RD Hannan, RB Pearson Growth factors 25 (4), 209-226, 2007 | 314 | 2007 |
Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis TJ Parmenter, M Kleinschmidt, KM Kinross, ST Bond, J Li, MR Kaadige, ... Cancer discovery 4 (4), 423-433, 2014 | 292 | 2014 |
STIM1: a novel phosphoprotein located at the cell surface SSM Manji, NJ Parker, RT Williams, L Van Stekelenburg, RB Pearson, ... Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000 | 290 | 2000 |
Targeting PI3 kinase/AKT/mTOR signaling in cancer K Sheppard, KM Kinross, B Solomon, RB Pearson, WA Phillips Critical Reviews™ in Oncogenesis 17 (1), 2012 | 288 | 2012 |
The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence. BE Kemp, RB Pearson, V Guerriero Jr, IC Bagchi, AR Means Journal of Biological Chemistry 262 (6), 2542-2548, 1987 | 286 | 1987 |
Substrate specificity of a multifunctional calmodulin-dependent protein kinase. RB Pearson, JR Woodgett, P Cohen, BE Kemp Journal of Biological Chemistry 260 (27), 14471-14476, 1985 | 283 | 1985 |
Targeting the nucleolus for cancer intervention JE Quin, JR Devlin, D Cameron, KM Hannan, RB Pearson, RD Hannan Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (6), 802-816, 2014 | 279 | 2014 |
AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy MV Astle, KM Hannan, PY Ng, RS Lee, AJ George, AK Hsu, Y Haupt, ... Oncogene 31 (15), 1949-1962, 2012 | 278 | 2012 |
Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis C Darido, SR Georgy, T Wilanowski, S Dworkin, A Auden, Q Zhao, ... Cancer cell 20 (5), 635-648, 2011 | 260 | 2011 |
Regulatory and structural motifs of chicken gizzard myosin light chain kinase. NJ Olson, RB Pearson, DS Needleman, MY Hurwitz, BE Kemp, AR Means Proceedings of the National Academy of Sciences 87 (6), 2284-2288, 1990 | 249 | 1990 |
UBF levels determine the number of active ribosomal RNA genes in mammals E Sanij, G Poortinga, K Sharkey, S Hung, TP Holloway, J Quin, E Robb, ... The Journal of cell biology 183 (7), 1259-1274, 2008 | 248 | 2008 |