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Rick Pearson
Rick Pearson
Group Leader, Peter MacCallum Cancer Centre
在 petermac.org 的电子邮件经过验证
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引用次数
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[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations
RB Pearson, BE Kemp
Methods in enzymology 200, 62-81, 1991
13011991
Protein kinase recognition sequence motifs
BE Kemp, RB Pearson
Trends in biochemical sciences 15 (9), 342-346, 1990
12891990
Rapamycin suppresses 5′ TOP mRNA translation through inhibition of p70s6k
HBJ Jefferies, S Fumagalli, PB Dennis, C Reinhard, RB Pearson, ...
The EMBO journal, 1997
12031997
Mutation of the PIK3CA gene in ovarian and breast cancer
IG Campbell, SE Russell, DYH Choong, KG Montgomery, ML Ciavarella, ...
Cancer research 64 (21), 7678-7681, 2004
11442004
A potent synthetic peptide inhibitor of the cAMP-dependent protein kinase.
HC Cheng, BE Kemp, RB Pearson, AJ Smith, L Misconi, SM Van Patten, ...
Journal of Biological Chemistry 261 (3), 989-992, 1986
6531986
The Akt kinase signals directly to endothelial nitric oxide synthase
BJ Michell, JE Griffiths, KI Mitchelhill, I Rodriguez-Crespo, T Tiganis, ...
Current biology 9 (15), 845-848, 1999
6141999
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53
MJ Bywater, G Poortinga, E Sanij, N Hein, A Peck, C Cullinane, M Wall, ...
Cancer cell 22 (1), 51-65, 2012
5772012
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar …
KM Hannan, Y Brandenburger, A Jenkins, K Sharkey, A Cavanaugh, ...
Molecular and cellular biology, 2003
5762003
The principal target of rapamycin‐induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.
RB Pearson, PB Dennis, JW Han, NA Williamson, SC Kozma, ...
The EMBO journal 14 (21), 5279-5287, 1995
5491995
Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function
K Jastrzebski, KM Hannan, EB Tchoubrieva, RD Hannan, RB Pearson
Growth factors 25 (4), 209-226, 2007
3142007
Response of BRAF-Mutant Melanoma to BRAF Inhibition Is Mediated by a Network of Transcriptional Regulators of Glycolysis
TJ Parmenter, M Kleinschmidt, KM Kinross, ST Bond, J Li, MR Kaadige, ...
Cancer discovery 4 (4), 423-433, 2014
2922014
STIM1: a novel phosphoprotein located at the cell surface
SSM Manji, NJ Parker, RT Williams, L Van Stekelenburg, RB Pearson, ...
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000
2902000
Targeting PI3 kinase/AKT/mTOR signaling in cancer
K Sheppard, KM Kinross, B Solomon, RB Pearson, WA Phillips
Critical Reviews™ in Oncogenesis 17 (1), 2012
2882012
The calmodulin binding domain of chicken smooth muscle myosin light chain kinase contains a pseudosubstrate sequence.
BE Kemp, RB Pearson, V Guerriero Jr, IC Bagchi, AR Means
Journal of Biological Chemistry 262 (6), 2542-2548, 1987
2861987
Substrate specificity of a multifunctional calmodulin-dependent protein kinase.
RB Pearson, JR Woodgett, P Cohen, BE Kemp
Journal of Biological Chemistry 260 (27), 14471-14476, 1985
2831985
Targeting the nucleolus for cancer intervention
JE Quin, JR Devlin, D Cameron, KM Hannan, RB Pearson, RD Hannan
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (6), 802-816, 2014
2792014
AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy
MV Astle, KM Hannan, PY Ng, RS Lee, AJ George, AK Hsu, Y Haupt, ...
Oncogene 31 (15), 1949-1962, 2012
2782012
Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis
C Darido, SR Georgy, T Wilanowski, S Dworkin, A Auden, Q Zhao, ...
Cancer cell 20 (5), 635-648, 2011
2602011
Regulatory and structural motifs of chicken gizzard myosin light chain kinase.
NJ Olson, RB Pearson, DS Needleman, MY Hurwitz, BE Kemp, AR Means
Proceedings of the National Academy of Sciences 87 (6), 2284-2288, 1990
2491990
UBF levels determine the number of active ribosomal RNA genes in mammals
E Sanij, G Poortinga, K Sharkey, S Hung, TP Holloway, J Quin, E Robb, ...
The Journal of cell biology 183 (7), 1259-1274, 2008
2482008
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