BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum T Kambara, LA Simms, VLJ Whitehall, KJ Spring, CVA Wynter, MD Walsh, ... Gut 53 (8), 1137-1144, 2004 | 913 | 2004 |
High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy KJ Spring, ZZ Zhao, R Karamatic, MD Walsh, VLJ Whitehall, T Pike, ... Gastroenterology 131 (5), 1400-1407, 2006 | 658 | 2006 |
ATM-dependent phosphorylation of nibrin in response to radiation exposure M Gatei, D Young, KM Cerosaletti, A Desai-Mehta, K Spring, S Kozlov, ... Nature genetics 25 (1), 115-119, 2000 | 625 | 2000 |
Interaction between ATM protein and c-Abl in response to DNA damage T Shafman, KK Khanna, P Kedar, K Spring, S Kozlov, T Yen, K Hobson, ... Nature 387 (6632), 520-523, 1997 | 609 | 1997 |
Cloning and expression of a protective antigen from the cattle tick Boophilus microplus. KN Rand, T Moore, A Sriskantha, K Spring, R Tellam, P Willadsen, ... Proceedings of the national academy of sciences 86 (24), 9657-9661, 1989 | 375 | 1989 |
Caffeine abolishes the mammalian G2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity BBS Zhou, P Chaturvedi, K Spring, SP Scott, RA Johanson, R Mishra, ... Journal of Biological Chemistry 275 (14), 10342-10348, 2000 | 362 | 2000 |
Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer K Spring, F Ahangari, SP Scott, P Waring, DM Purdie, PC Chen, ... Nature genetics 32 (1), 185-190, 2002 | 325 | 2002 |
Colorectal carcinogenesis: road maps to cancer DL Worthley, VL Whitehall, KJ Spring, BA Leggett World journal of gastroenterology: WJG 13 (28), 3784, 2007 | 252 | 2007 |
Promoter Hypermethylation Frequency and BRAF Mutations Distinguish Hereditary Non-Polyposis Colon Cancer from Sporadic MSI-H Colon Cancer A McGivern, CVA Wynter, VLJ Whitehall, T Kambara, KJ Spring, ... Familial cancer 3, 101-107, 2004 | 251 | 2004 |
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms D Watters, KK Khanna, H Beamish, G Birrell, K Spring, P Kedar, M Gatei, ... Oncogene 14 (16), 1911-1921, 1997 | 232 | 1997 |
Localization of a portion of extranuclear ATM to peroxisomes D Watters, P Kedar, K Spring, J Bjorkman, P Chen, M Gatei, G Birrell, ... Journal of Biological Chemistry 274 (48), 34277-34282, 1999 | 229 | 1999 |
Rapidly characterizing the fast dynamics of RNA genetic circuitry with cell-free transcription–translation (TX-TL) systems MK Takahashi, J Chappell, CA Hayes, ZZ Sun, J Kim, V Singhal, ... ACS synthetic biology 4 (5), 503-515, 2015 | 176 | 2015 |
Transactivation-deficient p73α (p73Δexon2) inhibits apoptosis and competes with p53 I Fillippovich, N Sorokina, M Gatei, Y Haupt, K Hobson, E Moallem, ... Oncogene 20 (4), 514-522, 2001 | 173 | 2001 |
Oxidative stress is responsible for deficient survival and dendritogenesis in purkinje neurons from ataxia-telangiectasia mutated mutant mice P Chen, C Peng, J Luff, K Spring, D Watters, S Bottle, S Furuya, MF Lavin Journal of Neuroscience 23 (36), 11453-11460, 2003 | 155 | 2003 |
Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype N Zhang, P Chen, KK Khanna, S Scott, M Gatei, S Kozlov, D Watters, ... Proceedings of the National Academy of Sciences 94 (15), 8021-8026, 1997 | 138 | 1997 |
Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer J Young, MA Barker, LA Simms, MD Walsh, KG Biden, D Buchanan, ... Clinical Gastroenterology and Hepatology 3 (3), 254-263, 2005 | 137 | 2005 |
Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development K Loh, JA Chia, S Greco, SJ Cozzi, RL Buttenshaw, CE Bond, LA Simms, ... Genes, Chromosomes and Cancer 47 (6), 449-460, 2008 | 109 | 2008 |
Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase MF Lavin, KK Khana, H Beamish, K Spring, D Watters, Y Shiloh Trends in biochemical sciences 20 (10), 382-383, 1995 | 109 | 1995 |
Role of inherited defects of MYH in the development of sporadic colorectal cancer T Kambara, VLJ Whitehall, KJ Spring, MA Barker, S Arnold, CVA Wynter, ... Genes, chromosomes and cancer 40 (1), 1-9, 2004 | 107 | 2004 |
Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics C Rosty, DD Buchanan, MD Walsh, SA Pearson, E Pavluk, RJ Walters, ... The American journal of surgical pathology 36 (6), 876-882, 2012 | 98 | 2012 |