The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling PP Hsu, SA Kang, J Rameseder, Y Zhang, KA Ottina, D Lim, TR Peterson, ... science 332 (6035), 1317-1322, 2011 | 1220 | 2011 |
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor N Kwiatkowski, T Zhang, PB Rahl, BJ Abraham, J Reddy, SB Ficarro, ... Nature 511 (7511), 616-620, 2014 | 856 | 2014 |
Phosphoproteome analysis of capacitated human sperm: evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation S Ficarro, O Chertihin, VA Westbrook, F White, F Jayes, P Kalab, JA Marto, ... Journal of Biological Chemistry 278 (13), 11579-11589, 2003 | 580 | 2003 |
Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma P Caro, AU Kishan, E Norberg, IA Stanley, B Chapuy, SB Ficarro, K Polak, ... Cancer cell 22 (4), 547-560, 2012 | 522 | 2012 |
Novel linear quadrupole ion trap/FT mass spectrometer: performance characterization and use in the comparative analysis of histone H3 post-translational modifications JEP Syka, JA Marto, DL Bai, S Horning, MW Senko, JC Schwartz, ... Journal of proteome research 3 (3), 621-626, 2004 | 459 | 2004 |
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins O Rozenblatt-Rosen, RC Deo, M Padi, G Adelmant, MA Calderwood, ... Nature 487 (7408), 491-495, 2012 | 422 | 2012 |
Subfemtomole MS and MS/MS peptide sequence analysis using nano-HPLC micro-ESI fourier transform ion cyclotron resonance mass spectrometry SE Martin, J Shabanowitz, DF Hunt, JA Marto Analytical Chemistry 72 (18), 4266-4274, 2000 | 422 | 2000 |
LIN28 regulates stem cell metabolism and conversion to primed pluripotency J Zhang, S Ratanasirintrawoot, S Chandrasekaran, Z Wu, SB Ficarro, ... Cell stem cell 19 (1), 66-80, 2016 | 367 | 2016 |
Discovery of potent and selective covalent inhibitors of JNK T Zhang, F Inesta-Vaquera, M Niepel, J Zhang, SB Ficarro, T Machleidt, ... Chemistry & biology 19 (1), 140-154, 2012 | 365 | 2012 |
Therapeutic targeting of oncogenic K‐Ras by a covalent catalytic site inhibitor SM Lim, KD Westover, SB Ficarro, RA Harrison, HG Choi, ME Pacold, ... Angewandte Chemie International Edition 53 (1), 199-204, 2014 | 350 | 2014 |
Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway KJ Kurppa, Y Liu, C To, T Zhang, M Fan, A Vajdi, EH Knelson, Y Xie, ... Cancer cell 37 (1), 104-122. e12, 2020 | 344 | 2020 |
Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously H Cho, CN Wivagg, M Kapoor, Z Barry, PDA Rohs, H Suh, JA Marto, ... Nature microbiology 1 (10), 1-8, 2016 | 325 | 2016 |
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors T Zhang, N Kwiatkowski, CM Olson, SE Dixon-Clarke, BJ Abraham, ... Nature chemical biology 12 (10), 876-884, 2016 | 319 | 2016 |
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Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding EC Twomey, Z Ji, TE Wales, NO Bodnar, SB Ficarro, JA Marto, JR Engen, ... Science 365 (6452), eaax1033, 2019 | 271 | 2019 |
Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis K Levanon, V Ng, HY Piao, Y Zhang, MC Chang, MH Roh, ... Oncogene 29 (8), 1103-1113, 2010 | 257 | 2010 |
In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C JC Hunter, D Gurbani, SB Ficarro, MA Carrasco, SM Lim, HG Choi, T Xie, ... Proceedings of the National Academy of Sciences 111 (24), 8895-8900, 2014 | 249 | 2014 |
Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene Z Chen, T Sasaki, X Tan, J Carretero, T Shimamura, D Li, C Xu, Y Wang, ... Cancer research 70 (23), 9827-9836, 2010 | 234 | 2010 |
Architecture of autoinhibited and active BRAF–MEK1–14-3-3 complexes E Park, S Rawson, K Li, BW Kim, SB Ficarro, GGD Pino, H Sharif, ... Nature 575 (7783), 545-550, 2019 | 232 | 2019 |
Viral mimicry of Cdc2/cyclin-dependent kinase 1 mediates disruption of nuclear lamina during human cytomegalovirus nuclear egress S Hamirally, JP Kamil, YM Ndassa-Colday, AJ Lin, WJ Jahng, MC Baek, ... PLoS pathogens 5 (1), e1000275, 2009 | 225 | 2009 |