Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing TH Jakobsen, M van Gennip, RK Phipps, MS Shanmugham, ... Antimicrobial agents and chemotherapy 56 (5), 2314-2325, 2012 | 512 | 2012 |
Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm M Alhede, KN Kragh, K Qvortrup, M Allesen-Holm, M van Gennip, ... PloS one 6 (11), e27943, 2011 | 316 | 2011 |
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes M Alhede, T Bjarnsholt, PØ Jensen, RK Phipps, C Moser, ... Microbiology 155 (11), 3500-3508, 2009 | 273 | 2009 |
Pseudomonas aeruginosa Biofilm Infections: Community Structure, Antimicrobial Tolerance and Immune Response M Rybtke, LD Hultqvist, M Givskov, T Tolker-Nielsen Journal of molecular biology 427 (23), 3628-3645, 2015 | 260 | 2015 |
Food as a Source for Quorum Sensing Inhibitors: Iberin from Horseradish Revealed as a Quorum Sensing Inhibitor of Pseudomonas aeruginosa TH Jakobsen, SK Bragason, RK Phipps, LD Christensen, M van Gennip, ... Applied and environmental microbiology 78 (7), 2410-2421, 2012 | 258 | 2012 |
Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes M Van Gennip, LD Christensen, M Alhede, R Phipps, PØ Jensen, ... Apmis 117 (7), 537-546, 2009 | 237 | 2009 |
Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an … LD Christensen, M Van Gennip, TH Jakobsen, M Alhede, HP Hougen, ... Journal of antimicrobial chemotherapy 67 (5), 1198-1206, 2012 | 204 | 2012 |
Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis M Kolpen, CR Hansen, T Bjarnsholt, C Moser, LD Christensen, ... Thorax 65 (1), 57-62, 2010 | 194 | 2010 |
Impact of Pseudomonas aeruginosa quorum sensing on biofilm persistence in an in vivo intraperitoneal foreign-body infection model LD Christensen, C Moser, PØ Jensen, TB Rasmussen, L Christophersen, ... Microbiology 153 (7), 2312-2320, 2007 | 180 | 2007 |
Clearance of Pseudomonas aeruginosa foreign-body biofilm infections through reduction of the cyclic di-GMP level in the bacteria LD Christensen, M van Gennip, MT Rybtke, H Wu, WC Chiang, M Alhede, ... Infection and immunity 81 (8), 2705-2713, 2013 | 106 | 2013 |
In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect T Bjarnsholt, M Van Gennip, TH Jakobsen, LD Christensen, PØ Jensen, ... Nature protocols 5 (2), 282-293, 2010 | 104 | 2010 |
Small molecule anti-biofilm agents developed on the basis of mechanistic understanding of biofilm formation K Qvortrup, LD Hultqvist, M Nilsson, TH Jakobsen, CU Jansen, J Uhd, ... Frontiers in chemistry 7, 742, 2019 | 95 | 2019 |
In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm–dispersed cells via c-di-GMP manipulation SL Chua, LD Hultqvist, M Yuan, M Rybtke, TE Nielsen, M Givskov, ... Nature protocols 10 (8), 1165-1180, 2015 | 86 | 2015 |
Interactions between Polymorphonuclear Leukocytes and Pseudomonas aeruginosa Biofilms on Silicone Implants In Vivo M van Gennip, LD Christensen, M Alhede, K Qvortrup, PØ Jensen, ... Infection and immunity 80 (8), 2601-2607, 2012 | 79 | 2012 |
Bacterial biofilm formation and treatment in soft tissue fillers M Alhede, Ö Er, S Eickhardt, K Kragh, M Alhede, LD Christensen, ... Pathogens and disease 70 (3), 339-346, 2014 | 70 | 2014 |
Identification of small molecules that interfere with c-di-GMP signaling and induce dispersal of Pseudomonas aeruginosa biofilms JB Andersen, LD Hultqvist, CU Jansen, TH Jakobsen, M Nilsson, ... NPJ biofilms and microbiomes 7 (1), 59, 2021 | 43 | 2021 |
Induction of native c-di-GMP phosphodiesterases leads to dispersal of Pseudomonas aeruginosa biofilms JB Andersen, KN Kragh, LD Hultqvist, M Rybtke, M Nilsson, TH Jakobsen, ... Antimicrobial Agents and Chemotherapy 65 (4), 10.1128/aac. 02431-20, 2021 | 30 | 2021 |
Qualitative and quantitative determination of quorum sensing inhibition in vitro TH Jakobsen, M van Gennip, LD Christensen, T Bjarnsholt, M Givskov Quorum Sensing: Methods and Protocols, 253-263, 2011 | 30 | 2011 |
Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa M Van Gennip, C Moser, LD Christensen, T Bjarnsholt, H Calum, ... Journal of antimicrobial chemotherapy 64 (6), 1241-1250, 2009 | 24 | 2009 |
Complex cases–Complex representations of problems B Bjerge, L Christensen, J Oute International Journal of Drug Policy 80, 102563, 2020 | 16 | 2020 |