3D virtual human atria: A computational platform for studying clinical atrial fibrillation OV Aslanidi, MA Colman, J Stott, H Dobrzynski, MR Boyett, AV Holden, ... Progress in biophysics and molecular biology 107 (1), 156-168, 2011 | 188 | 2011 |
Pro‐arrhythmogenic effects of atrial fibrillation‐induced electrical remodelling: insights from the three‐dimensional virtual human atria MA Colman, OV Aslanidi, S Kharche, MR Boyett, C Garratt, JC Hancox, ... The Journal of physiology 591 (17), 4249-4272, 2013 | 149 | 2013 |
Slow conduction in the border zones of patchy fibrosis stabilizes the drivers for atrial fibrillation: insights from multi-scale human atrial modeling R Morgan, MA Colman, H Chubb, G Seemann, OV Aslanidi Frontiers in physiology 7, 474, 2016 | 100 | 2016 |
Atrial heterogeneity generates re-entrant substrate during atrial fibrillation and anti-arrhythmic drug action: mechanistic insights from canine atrial models M Varela, MA Colman, JC Hancox, OV Aslanidi PLoS computational biology 12 (12), e1005245, 2016 | 55 | 2016 |
A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule … MA Colman, C Pinali, AW Trafford, H Zhang, A Kitmitto PLoS computational biology 13 (8), e1005714, 2017 | 52 | 2017 |
Heterogeneous and anisotropic integrative model of pulmonary veins: computational study of arrhythmogenic substrate for atrial fibrillation OV Aslanidi, MA Colman, M Varela, J Zhao, BH Smaill, JC Hancox, ... Interface focus 3 (2), 20120069, 2013 | 49 | 2013 |
Three-dimensional and chemical mapping of intracellular signaling nanodomains in health and disease with enhanced expansion microscopy TMD Sheard, ME Hurley, J Colyer, E White, R Norman, E Pervolaraki, ... ACS nano 13 (2), 2143-2157, 2019 | 48 | 2019 |
Evolution and pharmacological modulation of the arrhythmogenic wave dynamics in canine pulmonary vein model MA Colman, M Varela, JC Hancox, H Zhang, OV Aslanidi Europace 16 (3), 416-423, 2014 | 44 | 2014 |
Arrhythmia mechanisms and spontaneous calcium release: Bi-directional coupling between re-entrant and focal excitation MA Colman PLoS computational biology 15 (8), e1007260, 2019 | 40 | 2019 |
Comparison of electric-and magnetic-cardiograms produced by myocardial ischemia in models of the human ventricle and torso EAP Alday, H Ni, C Zhang, MA Colman, Z Gan, H Zhang PLoS One 11 (8), e0160999, 2016 | 32 | 2016 |
Correlation between P-wave morphology and origin of atrial focal tachycardia—insights from realistic models of the human atria and torso MA Colman, OV Aslanidi, J Stott, AV Holden, H Zhang IEEE Transactions on Biomedical Engineering 58 (10), 2952-2955, 2011 | 32 | 2011 |
Virtual tissue engineering of the human atrium: modelling pharmacological actions on atrial arrhythmogenesis OV Aslanidi, M Al-Owais, AP Benson, M Colman, CJ Garratt, SH Gilbert, ... European Journal of Pharmaceutical Sciences 46 (4), 209-221, 2012 | 31 | 2012 |
Human Atrial Arrhythmogenesis and Sinus Bradycardia in KCNQ1-Linked Short QT Syndrome: Insights From Computational Modelling DG Whittaker, MA Colman, H Ni, JC Hancox, H Zhang Frontiers in physiology 9, 1402, 2018 | 30 | 2018 |
A new algorithm to diagnose Atrial ectopic origin from multi lead ECG systems-insights from 3D virtual human Atria and Torso EAP Alday, MA Colman, P Langley, TD Butters, J Higham, AJ Workman, ... PLoS computational biology 11 (1), e1004026, 2015 | 29 | 2015 |
Effects of human atrial ionic remodelling by β-blocker therapy on mechanisms of atrial fibrillation: a computer simulation SR Kharche, T Stary, MA Colman, IV Biktasheva, AJ Workman, AC Rankin, ... Europace 16 (10), 1524-1533, 2014 | 27 | 2014 |
In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis MA Colman, H Ni, B Liang, N Schmitt, H Zhang PLoS Computational Biology 13 (6), e1005587, 2017 | 26 | 2017 |
Trigger vs. substrate: multi-dimensional modulation of QT-prolongation associated arrhythmic dynamics by a hERG channel activator MA Colman, EA Perez Alday, AV Holden, AP Benson Frontiers in Physiology 8, 757, 2017 | 23 | 2017 |
Dynamic clamping human and rabbit atrial calcium current: narrowing ICaL window abolishes early afterdepolarizations S Kettlewell, P Saxena, J Dempster, MA Colman, RC Myles, GL Smith, ... The Journal of physiology 597 (14), 3619-3638, 2019 | 22 | 2019 |
Multi-scale computational modeling of spatial calcium handling from nanodomain to whole-heart: Overview and perspectives MA Colman, E Alvarez-Lacalle, B Echebarria, D Sato, H Sutanto, ... Frontiers in physiology 13, 836622, 2022 | 18 | 2022 |
Multi-scale approaches for the simulation of cardiac electrophysiology: II–Tissue-level structure and function AP Benson, HJ Stevenson-Cocks, DG Whittaker, E White, MA Colman Methods 185, 60-81, 2021 | 17 | 2021 |