SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ... Nature medicine 26 (5), 681-687, 2020 | 2745 | 2020 |
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ... Cell 181 (5), 1016-1035. e19, 2020 | 2381 | 2020 |
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis Y Xu, T Mizuno, A Sridharan, Y Du, M Guo, J Tang, ... JCI insight 1 (20), 2016 | 512 | 2016 |
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production G Chen, TR Korfhagen, Y Xu, J Kitzmiller, SE Wert, Y Maeda, A Gregorieff, ... The Journal of clinical investigation 119 (10), 2914-2924, 2009 | 432 | 2009 |
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway CL Karp, LM Flick, KW Park, S Softic, TM Greer, R Keledjian, R Yang, ... Nature immunology 5 (4), 388-392, 2004 | 420 | 2004 |
SINCERA: a pipeline for single-cell RNA-Seq profiling analysis M Guo, H Wang, SS Potter, JA Whitsett, Y Xu PLoS computational biology 11 (11), e1004575, 2015 | 357 | 2015 |
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis H Wan, S Dingle, Y Xu, V Besnard, KH Kaestner, SL Ang, S Wert, ... Journal of Biological Chemistry 280 (14), 13809-13816, 2005 | 321 | 2005 |
Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms S Xiao, N Yosef, J Yang, Y Wang, L Zhou, C Zhu, C Wu, E Baloglu, ... Immunity 40 (4), 477-489, 2014 | 315 | 2014 |
Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung AW Lange, A Sridharan, Y Xu, BR Stripp, AK Perl, JA Whitsett Journal of molecular cell biology 7 (1), 35-47, 2015 | 207 | 2015 |
β-Catenin regulates differentiation of respiratory epithelial cells in vivo ML Mucenski, JM Nation, AR Thitoff, V Besnard, Y Xu, SE Wert, N Harada, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 289 (6 …, 2005 | 203 | 2005 |
TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression M DeFelice, D Silberschmidt, R DiLauro, Y Xu, SE Wert, TE Weaver, ... Journal of Biological Chemistry 278 (37), 35574-35583, 2003 | 202 | 2003 |
An integrated cell atlas of the lung in health and disease L Sikkema, C Ramírez-Suástegui, DC Strobl, TE Gillett, L Zappia, ... Nature medicine 29 (6), 1563-1577, 2023 | 194 | 2023 |
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C M Dong, JP Bridges, K Apsley, Y Xu, TE Weaver Molecular biology of the cell 19 (6), 2620-2630, 2008 | 193 | 2008 |
Role of Sonic hedgehog in patterning of tracheal–bronchial cartilage and the peripheral lung LAD Miller, SE Wert, JC Clark, Y Xu, AKT Perl, JA Whitsett Developmental dynamics: an official publication of the American Association …, 2004 | 186 | 2004 |
Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth M Guo, Y Du, JJ Gokey, S Ray, SM Bell, M Adam, P Sudha, AK Perl, ... Nature communications 10 (1), 37, 2019 | 185 | 2019 |
Building and regenerating the lung cell by cell JA Whitsett, TV Kalin, Y Xu, VV Kalinichenko Physiological reviews 99 (1), 513-554, 2019 | 172 | 2019 |
C/EBPα is required for lung maturation at birth PC Martis, JA Whitsett, Y Xu, AKT Perl, H Wan, M Ikegami Oxford University Press for The Company of Biologists Limited 133 (6), 1155-1164, 2006 | 172 | 2006 |
SLICE: determining cell differentiation and lineage based on single cell entropy M Guo, EL Bao, M Wagner, JA Whitsett, Y Xu Nucleic acids research 45 (7), e54-e54, 2017 | 166 | 2017 |
Foxa2 is required for transition to air breathing at birth H Wan, Y Xu, M Ikegami, MT Stahlman, KH Kaestner, SL Ang, JA Whitsett Proceedings of the National Academy of Sciences 101 (40), 14449-14454, 2004 | 164 | 2004 |
KrasG12D and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung Y Maeda, T Tsuchiya, H Hao, DH Tompkins, Y Xu, ML Mucenski, L Du, ... The Journal of clinical investigation 122 (12), 4388-4400, 2012 | 160 | 2012 |