Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism M Ouimet, S Koster, E Sakowski, B Ramkhelawon, C Van Solingen, ... Nature immunology 17 (6), 677-686, 2016 | 352 | 2016 |
Controlled shedding of platelet glycoprotein (GP) VI and GPIb–IX–V by ADAM family metalloproteinases EE Gardiner, D Karunakaran, Y Shen, JF Arthur, RK Andrews, MC Berndt Journal of Thrombosis and Haemostasis 5 (7), 1530-1537, 2007 | 318 | 2007 |
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis D Karunakaran, M Geoffrion, L Wei, W Gan, L Richards, P Shangari, ... Science advances 2 (7), e1600224, 2016 | 256 | 2016 |
Extracellular vesicles secreted by atherogenic macrophages transfer microRNA to inhibit cell migration MA Nguyen, D Karunakaran, M Geoffrion, HS Cheng, K Tandoc, ... Arteriosclerosis, thrombosis, and vascular biology 38 (1), 49-63, 2018 | 207 | 2018 |
Macrophage mitochondrial energy status regulates cholesterol efflux and is enhanced by anti-miR33 in atherosclerosis D Karunakaran, AB Thrush, MA Nguyen, L Richards, M Geoffrion, ... Circulation research 117 (3), 266-278, 2015 | 178 | 2015 |
Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity RK Andrews, D Karunakaran, EE Gardiner, MC Berndt Arteriosclerosis, thrombosis, and vascular biology 27 (7), 1511-1520, 2007 | 132 | 2007 |
The walking dead: macrophage inflammation and death in atherosclerosis MM Kavurma, KJ Rayner, D Karunakaran Current opinion in lipidology 28 (2), 91-98, 2017 | 123 | 2017 |
RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and … D Karunakaran, MA Nguyen, M Geoffrion, D Vreeken, Z Lister, HS Cheng, ... Circulation 143 (2), 163-177, 2021 | 119 | 2021 |
Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcγRIIa EE Gardiner, D Karunakaran, JF Arthur, FT Mu, MS Powell, RI Baker, ... Blood, The Journal of the American Society of Hematology 111 (1), 165-174, 2008 | 97 | 2008 |
Therapeutic inhibition of miR-33 promotes fatty acid oxidation but does not ameliorate metabolic dysfunction in diet-induced obesity D Karunakaran, L Richards, M Geoffrion, D Barrette, RJ Gotfrit, ME Harper, ... Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2536-2543, 2015 | 73 | 2015 |
Compromised ITAM‐based platelet receptor function in a patient with immune thrombocytopenic purpura EE Gardiner, M AL‐TAMIMI, FT MU, D Karunakaran, JY Thom, M Moroi, ... Journal of Thrombosis and Haemostasis 6 (7), 1175-1182, 2008 | 70 | 2008 |
GPIbα-selective activation of platelets induces platelet signaling events comparable to GPVI activation events EE Gardiner, JF Arthur, Y Shen, D Karunakaran, LA Moore, JS Am Esch, ... Platelets 21 (4), 244-252, 2010 | 61 | 2010 |
Phagocytosis of IgG‐coated polystyrene beads by macrophages induces and requires high membrane order A Magenau, C Benzing, N Proschogo, AS Don, L Hejazi, D Karunakaran, ... Traffic 12 (12), 1730-1743, 2011 | 50 | 2011 |
Programmed autologous cleavage of platelet receptors MC Berndt, D Karunakaran, EE Gardiner, RK Andrews Journal of Thrombosis and Haemostasis 5, 212-219, 2007 | 46 | 2007 |
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice D Karunakaran, AW Turner, AC Duchez, S Soubeyrand, A Rasheed, ... Nature metabolism 2 (10), 1113-1125, 2020 | 40 | 2020 |
Epigenetic silencing of RIPK3 in hepatocytes prevents MLKL-mediated necroptosis from contributing to liver pathologies SP Preston, MD Stutz, CC Allison, U Nachbur, Q Gouil, BM Tran, ... Gastroenterology 163 (6), 1643-1657. e14, 2022 | 38 | 2022 |
Macrophage miRNAs in atherosclerosis D Karunakaran, KJ Rayner Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 35 | 2016 |
MicroRNAs in cardiovascular health: from order to disorder D Karunakaran, KJ Rayner Endocrinology 154 (11), 4000-4009, 2013 | 27 | 2013 |
Protein kinase C controls vesicular transport and secretion of apolipoprotein E from primary human macrophages D Karunakaran, M Kockx, DM Owen, JR Burnett, W Jessup, L Kritharides Journal of Biological Chemistry 288 (7), 5186-5197, 2013 | 26 | 2013 |
Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease Y Wang, R Abrol, JYW Mak, K Das Gupta, D Ramnath, D Karunakaran, ... The FEBS journal 290 (11), 2805-2832, 2023 | 24 | 2023 |