Differential evolution and neofunctionalization of snake venom metalloprotease domains A Brust, K Sunagar, EAB Undheim, I Vetter, DC Yang, NR Casewell, ... Molecular & Cellular Proteomics 12 (3), 651-663, 2013 | 110 | 2013 |
Cone snail venomics: from novel biology to novel therapeutics JR Prashanth, A Brust, AH Jin, PF Alewood, S Dutertre, RJ Lewis Future medicinal chemistry 6 (15), 1659-1675, 2014 | 96 | 2014 |
χ-Conopeptide pharmacophore development: Toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain A Brust, E Palant, DE Croker, B Colless, R Drinkwater, B Patterson, ... Journal of medicinal chemistry 52 (22), 6991-7002, 2009 | 96 | 2009 |
Libraries of peptide conjugates and methods for making them AF Brust US Patent App. 13/061,744, 2011 | 81 | 2011 |
High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain LJ Drew, F Rugiero, P Cesare, JE Gale, B Abrahamsen, S Bowden, ... PloS one 2 (6), e515, 2007 | 81 | 2007 |
Sugar-derived building blocks. Part 26. Part 25. See ref. 1. Hydrophilic pyrroles, pyridazines and diazepinones from d-fructose and isomaltulose FW Lichtenthaler, A Brust, E Cuny Green Chemistry 3 (5), 201-209, 2001 | 75 | 2001 |
The snake with the scorpion’s sting: Novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus) DC Yang, JR Deuis, D Dashevsky, J Dobson, TNW Jackson, A Brust, ... Toxins 8 (10), 303, 2016 | 69 | 2016 |
Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors MC Inserra, SN Kompella, I Vetter, A Brust, NL Daly, H Cuny, DJ Craik, ... Biochemical pharmacology 86 (6), 791-799, 2013 | 65 | 2013 |
Phosphorylation and metabolism of sucrose and its five linkage-isomeric α-D-glucosyl-D-fructoses by Klebsiella pneumoniae J Thompson, SA Robrish, A Pikis, A Brust, FW Lichtenthaler Carbohydrate Research 331 (2), 149-161, 2001 | 62 | 2001 |
Understanding the molecular basis of toxin promiscuity: The analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping … JE Jensen, B Cristofori-Armstrong, R Anangi, KJ Rosengren, CHY Lau, ... Journal of medicinal chemistry 57 (21), 9195-9203, 2014 | 55 | 2014 |
Gomesin inhibits melanoma growth by manipulating key signaling cascades that control cell death and proliferation MP Ikonomopoulou, MA Fernandez-Rojo, SS Pineda, P Cabezas-Sainz, ... Scientific reports 8 (1), 11519, 2018 | 50 | 2018 |
Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors AA Grishin, H Cuny, A Hung, RJ Clark, A Brust, K Akondi, PF Alewood, ... Journal of Biological Chemistry 288 (48), 34428-34442, 2013 | 50 | 2013 |
Stabilization of the Cysteine‐Rich Conotoxin MrIA by Using a 1, 2, 3‐Triazole as a Disulfide Bond Mimetic A Gori, CIA Wang, PJ Harvey, KJ Rosengren, RF Bhola, ML Gelmi, ... Angewandte Chemie International Edition 54 (4), 1361-1364, 2015 | 47 | 2015 |
Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3 JE Jensen, M Mobli, A Brust, PF Alewood, GF King, LD Rash Marine Drugs 10 (7), 1511-1527, 2012 | 38 | 2012 |
Structural mechanisms for α-conotoxin activity at the human α3β4 nicotinic acetylcholine receptor N Abraham, M Healy, L Ragnarsson, A Brust, PF Alewood, RJ Lewis Scientific reports 7 (1), 45466, 2017 | 34 | 2017 |
Conopeptide-derived κ-opioid agonists (Conorphins): potent, selective, and metabolic stable dynorphin A mimetics with antinociceptive properties A Brust, DE Croker, B Colless, L Ragnarsson, Å Andersson, K Jain, ... Journal of medicinal chemistry 59 (6), 2381-2395, 2016 | 34 | 2016 |
Conopeptide ρ-TIA Defines a New Allosteric Site on the Extracellular Surface of the α1B-Adrenoceptor*♦ L Ragnarsson, CIA Wang, Å Andersson, D Fajarningsih, T Monks, A Brust, ... Journal of biological chemistry 288 (3), 1814-1827, 2013 | 32 | 2013 |
Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter A Brust, CIA Wang, NL Daly, J Kennerly, M Sadeghi, MJ Christie, ... Wiley, 2013 | 30 | 2013 |
Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi SR Sousa, JS Wingerd, A Brust, C Bladen, L Ragnarsson, V Herzig, ... PLoS One 12 (9), e0182848, 2017 | 29 | 2017 |
High‐throughput synthesis of conopeptides: a safety‐catch linker approach enabling disulfide formation in 96‐well format A Brust, AE Tickle Journal of Peptide Science: An Official Publication of the European Peptide …, 2007 | 29 | 2007 |