Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians NM Davies, MV Holmes, GD Smith bmj 362, 2018 | 2467 | 2018 |
Guidelines for performing Mendelian randomization investigations: update for summer 2023 S Burgess, GD Smith, NM Davies, F Dudbridge, D Gill, MM Glymour, ... Wellcome open research 4, 2019 | 1168 | 2019 |
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium The Lancet 379 (9822), 1214-1224, 2012 | 1075 | 2012 |
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data MV Holmes, CE Dale, L Zuccolo, RJ Silverwood, Y Guo, Z Ye, ... Bmj 349, g4164, 2014 | 820 | 2014 |
Mendelian randomization of blood lipids for coronary heart disease MV Holmes, FW Asselbergs, TM Palmer, F Drenos, MB Lanktree, ... European heart journal 36 (9), 539-550, 2015 | 773 | 2015 |
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials DI Swerdlow, D Preiss, KB Kuchenbaecker, MV Holmes, JEL Engmann, ... The Lancet 385 (9965), 351-361, 2015 | 743 | 2015 |
Mendelian randomization E Sanderson, MM Glymour, MV Holmes, H Kang, J Morrison, MR Munafò, ... Nature Reviews Methods Primers 2 (1), 6, 2022 | 632 | 2022 |
Meta‐analysis and Mendelian randomization: a review J Bowden, MV Holmes Research synthesis methods 10 (4), 486-496, 2019 | 619 | 2019 |
CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis MV Holmes, P Perel, T Shah, AD Hingorani, JP Casas Jama 306 (24), 2704-2714, 2011 | 615 | 2011 |
Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: a multivariable Mendelian randomisation analysis TG Richardson, E Sanderson, TM Palmer, M Ala-Korpela, BA Ference, ... PLoS medicine 17 (3), e1003062, 2020 | 570 | 2020 |
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ... Nature communications 11 (1), 163, 2020 | 561 | 2020 |
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality MV Holmes, M Ala-Korpela, GD Smith Nature Reviews Cardiology 14 (10), 577-590, 2017 | 524 | 2017 |
Association between diabetes and cause-specific mortality in rural and urban areas of China F Bragg, MV Holmes, A Iona, Y Guo, H Du, Y Chen, Z Bian, L Yang, ... Jama 317 (3), 280-289, 2017 | 498 | 2017 |
Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China IY Millwood, RG Walters, XW Mei, Y Guo, L Yang, Z Bian, DA Bennett, ... The Lancet 393 (10183), 1831-1842, 2019 | 450 | 2019 |
The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 432 | 2021 |
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials MV Holmes, P Newcombe, JA Hubacek, R Sofat, SL Ricketts, J Cooper, ... The Lancet 378 (9791), 584-594, 2011 | 422 | 2011 |
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ... Nature genetics 52 (10), 1122-1131, 2020 | 395 | 2020 |
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study AF Schmidt, DI Swerdlow, MV Holmes, RS Patel, Z Fairhurst-Hunter, ... The lancet Diabetes & endocrinology 5 (2), 97-105, 2017 | 392 | 2017 |
Lipids, lipoproteins, and metabolites and risk of myocardial infarction and stroke MV Holmes, IY Millwood, C Kartsonaki, MR Hill, DA Bennett, R Boxall, ... Journal of The American college of cardiology 71 (6), 620-632, 2018 | 389 | 2018 |
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ... Nature metabolism 2 (10), 1135-1148, 2020 | 385 | 2020 |