Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms H Bagci, N Sriskandarajah, A Robert, J Boulais, IE Elkholi, V Tran, ZY Lin, ... Nature Cell Biology, 2019 | 149 | 2019 |
Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels MA Goyette, IE Elkholi, C Apcher, H Kuasne, CV Rothlin, WJ Muller, ... Proceedings of the National Academy of Sciences 118 (29), e2023868118, 2021 | 47 | 2021 |
AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer MA Goyette, R Cusseddu, I Elkholi, A Abu-Thuraia, N El-Hachem, ... Oncotarget 10 (21), 2055-2067, 2019 | 40 | 2019 |
Tissue plasminogen activator-based clot busting: Controlled delivery approaches IM El-Sherbiny, IE Elkholi, MH Yacoub Global Cardiology Science and Practice 2014 (3), 46, 2014 | 38 | 2014 |
Organophosphorus Flame Retardants (OPFR): Neurotoxicity QW MB Abou-Donia, M Salama, M Elgamal, I Elkholi Journal of Environment and Health Science 2 (1), 1-29, 2016 | 26 | 2016 |
Evaluation of Anti-Cancer Potential of Capsaicin-Loaded Trimethyl Chitosan-Based Nanoparticles in HepG2 Hepatocarcinoma Cells I Elkholi, N Hazem, W El-Kashef, MA Sobh, D Shaalan, M Sobh, ... J Nanomed Nanotechnol 5 (6), article 240, 2014 | 21 | 2014 |
Breast cancer metastatic dormancy and relapse: An enigma of microenvironment (s) IE Elkholi, A Lalonde, M Park, JF Côté Cancer Research 82 (24), 4497-4510, 2022 | 20 | 2022 |
Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry K Leguay, B Decelle, IE Elkholi, M Bouvier, JF Côté, S Carréno Journal of Cell Biology 221 (6), e202109065, 2022 | 16 | 2022 |
Myoglobin: From physiological roles to potential implications in cancer IE Elkholi, ME Elsherbiny, M Emara Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1877 (3), 188706, 2022 | 15 | 2022 |
Shedding of cancer susceptibility candidate 4 by the convertases PC7/furin unravels a novel secretory protein implicated in cancer progression S Duval, A Abu-Thuraia, IE Elkholi, R Chen, D Seebun, J Mayne, JF Côté, ... Cell Death & Disease 11 (8), 665, 2020 | 14 | 2020 |
Investigating the causal role of MRE11A p. E506* in breast and ovarian cancer IE Elkholi, M Di Iorio, S Fahiminiya, SL Arcand, HR Han, C Nogué, S Behl, ... Scientific Reports 11 (1), 2409, 2021 | 9 | 2021 |
MRN complex and cancer risk: old bottles, new wine IE Elkholi, WD Foulkes, B Rivera Clinical Cancer Research, 2021 | 8 | 2021 |
Myoglobin variants are expressed in human glioblastoma cells‑hypoxia effect? R El‑Tohamy, I Elkholi, ME Elsherbiny, M Magdy, O Hammam, ... Oncology Reports, 2020 | 6 | 2020 |
Expression of Myoglobin in Normal and Cancer Brain Tissues: Correlation With Hypoxia Markers. ME Elsherbiny, M Shaaban, R El-Tohamy, IE Elkholi, OA Hammam, ... Frontiers in Oncology 11, 590771, 2021 | 5 | 2021 |
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex I Elkholi, J Boulais, MP Thibault, HD Phan, A Robert, L Lai, D Faubert, ... Journal of Biological Chemistry 299 (ISSUE 9), 105123, 2023 | 1 | 2023 |
How can we integrate the biology of breast cancer cell dormancy into clinical practice? IE Elkholi, AAN Rose, JA Aguirre-Ghiso, JF Côté Cancer Cell, 2024 | | 2024 |
Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation IE Elkholi, A Robert, H Kuasne, S Drapela, G Macleod, S Hebert, A Pacis, ... bioRxiv, 2023.08. 02.551681, 2023 | | 2023 |
Genomic approaches to determine genes that regulate breast cancer metastatic dormancy and relapse I Elkholi | | 2023 |