Cellular and molecular mechanisms of metformin: an overview B Viollet, B Guigas, NS Garcia, J Leclerc, M Foretz, F Andreelli Clinical science 122 (6), 253-270, 2012 | 2172 | 2012 |
Metformin: from mechanisms of action to therapies M Foretz, B Guigas, L Bertrand, M Pollak, B Viollet Cell metabolism 20 (6), 953-966, 2014 | 1387 | 2014 |
Activation of AMP‐activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders B Viollet, M Foretz, B Guigas, S Horman, R Dentin, L Bertrand, L Hue, ... The Journal of physiology 574 (1), 41-53, 2006 | 651 | 2006 |
AMP‐activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives B Viollet, B Guigas, J Leclerc, S Hébrard, L Lantier, R Mounier, F Andreelli, ... Acta physiologica 196 (1), 81-98, 2009 | 567 | 2009 |
Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus M Foretz, B Guigas, B Viollet Nature Reviews Endocrinology 15 (10), 569-589, 2019 | 520 | 2019 |
AMPK: Lessons from transgenic and knockout animals B Viollet, Y Athea, R Mounier, B Guigas, E Zarrinpashneh, S Horman, ... Frontiers in bioscience (Landmark edition) 14, 19, 2009 | 357 | 2009 |
The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin C Batandier, B Guigas, D Detaille, M El-Mir, E Fontaine, M Rigoulet, ... Journal of bioenergetics and biomembranes 38, 33-42, 2006 | 351 | 2006 |
Metformin activates AMP-activated protein kinase in primary human hepatocytes by decreasing cellular energy status X Stephenne, M Foretz, N Taleux, GC Van Der Zon, E Sokal, L Hue, ... Diabetologia 54, 3101-3110, 2011 | 335 | 2011 |
Metformin prevents high-glucose–induced endothelial cell death through a mitochondrial permeability transition-dependent process D Detaille, B Guigas, C Chauvin, C Batandier, E Fontaine, ... Diabetes 54 (7), 2179-2187, 2005 | 331 | 2005 |
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons MY El-Mir, D Detaille, G R-Villanueva, M Delgado-Esteban, B Guigas, ... Journal of Molecular Neuroscience 34, 77-87, 2008 | 282 | 2008 |
Role of mitochondria in the mechanism (s) of action of metformin G Vial, D Detaille, B Guigas Frontiers in endocrinology 10, 442419, 2019 | 257 | 2019 |
5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase–independent effect on glucokinase … B Guigas, L Bertrand, N Taleux, M Foretz, N Wiernsperger, D Vertommen, ... Diabetes 55 (4), 865-874, 2006 | 218 | 2006 |
Chronic helminth infection and helminth‐derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice L Hussaarts, N García‐Tardón, L van Beek, MM Heemskerk, S Haeberlein, ... The FASEB Journal, 3027-3039, 2015 | 215 | 2015 |
Role of AMP kinase and PPARδ in the regulation of lipid and glucose metabolism in human skeletal muscle DK Krämer, L Al-Khalili, B Guigas, Y Leng, PM Garcia-Roves, A Krook Journal of Biological Chemistry 282 (27), 19313-19320, 2007 | 211 | 2007 |
Mitochondrial metabolism and type-2 diabetes: a specific target of metformin XM Leverve, B Guigas, D Detaille, C Batandier, EA Koceir, C Chauvin, ... Diabetes & metabolism 29 (4), 6S88-6S94, 2003 | 189 | 2003 |
Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice JJ Geerling, MR Boon, GC van der Zon, SAA van den Berg, ... Diabetes 63 (3), 880-891, 2014 | 188 | 2014 |
Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study B Guigas, D Detaille, C Chauvin, C Batandier, F De Oliveira, E Fontaine, ... Biochemical journal 382 (3), 877-884, 2004 | 185 | 2004 |
AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B L Bertrand, A Ginion, C Beauloye, AD Hebert, B Guigas, L Hue, ... American Journal of Physiology-Heart and Circulatory Physiology 291 (1 …, 2006 | 177 | 2006 |
Interleukin-33-activated islet-resident innate lymphoid cells promote insulin secretion through myeloid cell retinoic acid production E Dalmas, FM Lehmann, E Dror, S Wueest, C Thienel, M Borsigova, ... Immunity 47 (5), 928-942. e7, 2017 | 154 | 2017 |
Gene expression analysis of mTOR pathway: association with human longevity WM Passtoors, M Beekman, J Deelen, R van der Breggen, AB Maier, ... Aging Cell 12 (1), 24-31, 2013 | 150 | 2013 |