Tumor-induced stromal reprogramming drives lymph node transformation A Riedel, D Shorthouse, L Haas, BA Hall, J Shields Nature immunology 17 (9), 1118-1127, 2016 | 161 | 2016 |
Computing clinically relevant binding free energies of HIV-1 protease inhibitors DW Wright, BA Hall, OA Kenway, S Jha, PV Coveney Journal of chemical theory and computation 10 (3), 1228-1241, 2014 | 144 | 2014 |
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium B Colom, MP Alcolea, G Piedrafita, MWJ Hall, A Wabik, SC Dentro, ... Nature genetics 52 (6), 604-614, 2020 | 129 | 2020 |
Mutant clones in normal epithelium outcompete and eliminate emerging tumours B Colom, A Herms, MWJ Hall, SC Dentro, C King, RK Sood, MP Alcolea, ... Nature 598 (7881), 510-514, 2021 | 117 | 2021 |
Dynamite: a simple way to gain insight into protein motions CP Barrett, BA Hall, MEM Noble Acta Crystallographica Section D: Biological Crystallography 60 (12), 2280-2287, 2004 | 108 | 2004 |
Changes in transmembrane helix alignment by arginine residues revealed by solid-state NMR experiments and coarse-grained MD simulations VV Vostrikov, BA Hall, DV Greathouse, RE Koeppe, MSP Sansom Journal of the American Chemical Society 132 (16), 5803-5811, 2010 | 100 | 2010 |
Role of the C-terminal domain in the structure and function of tetrameric sodium channels C Bagnéris, PG DeCaen, BA Hall, CE Naylor, DE Clapham, CWM Kay, ... Nature communications 4 (1), 2465, 2013 | 94 | 2013 |
Epidermal tissue adapts to restrain progenitors carrying clonal p53 mutations K Murai, G Skrupskelyte, G Piedrafita, M Hall, V Kostiou, SH Ong, T Nagy, ... Cell stem cell 23 (5), 687-699. e8, 2018 | 88 | 2018 |
Selection of oncogenic mutant clones in normal human skin varies with body site JC Fowler, C King, C Bryant, MWJ Hall, R Sood, SH Ong, E Earp, ... Cancer discovery 11 (2), 340-361, 2021 | 78 | 2021 |
Structural flexibility of the macrophage dengue virus receptor CLEC5A: implications for ligand binding and signaling AA Watson, AA Lebedev, BA Hall, AE Fenton-May, AA Vagin, ... Journal of Biological Chemistry 286 (27), 24208-24218, 2011 | 66 | 2011 |
A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice G Piedrafita, V Kostiou, A Wabik, B Colom, D Fernandez-Antoran, ... Nature communications 11 (1), 1429, 2020 | 65 | 2020 |
Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity FK Turrell, EM Kerr, M Gao, H Thorpe, GJ Doherty, J Cridge, ... Genes & development 31 (13), 1339-1353, 2017 | 64 | 2017 |
Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating S Haider, A Grottesi, BA Hall, FM Ashcroft, MSP Sansom Biophysical journal 88 (5), 3310-3320, 2005 | 63 | 2005 |
Conformational dynamics of M2 helices in KirBac channels: helix flexibility in relation to gating via molecular dynamics simulations A Grottesi, C Domene, B Hall, MSP Sansom Biochemistry 44 (44), 14586-14594, 2005 | 60 | 2005 |
Exploring peptide-membrane interactions with coarse-grained MD simulations BA Hall, AP Chetwynd, MSP Sansom Biophysical journal 100 (8), 1940-1948, 2011 | 59 | 2011 |
Transmembrane helix dynamics of bacterial chemoreceptors supports a piston model of signalling BA Hall, JP Armitage, MSP Sansom PLoS computational biology 7 (10), e1002204, 2011 | 54 | 2011 |
Mechanism of bacterial signal transduction revealed by molecular dynamics of Tsr dimers and trimers of dimers in lipid vesicles BA Hall, JP Armitage, MSP Sansom Public Library of Science 8 (9), e1002685, 2012 | 50 | 2012 |
Coarse-grain simulations reveal movement of the synaptobrevin C-terminus in response to piconewton forces M Lindau, BA Hall, A Chetwynd, O Beckstein, MSP Sansom Biophysical journal 103 (5), 959-969, 2012 | 48 | 2012 |
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth E Abby, SC Dentro, MWJ Hall, JC Fowler, SH Ong, R Sood, A Herms, ... Nature Genetics 55 (2), 232-245, 2023 | 46 | 2023 |
A helix heterodimer in a lipid bilayer: prediction of the structure of an integrin transmembrane domain via multiscale simulations AC Kalli, BA Hall, ID Campbell, MSP Sansom Structure 19 (10), 1477-1484, 2011 | 43 | 2011 |