Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential RM Labbé, A Holowatyj, ZQ Yang American journal of translational research 6 (1), 1, 2014 | 178 | 2014 |
Genetic alterations of histone lysine methyltransferases and their significance in breast cancer L Liu, S Kimball, H Liu, A Holowatyj, ZQ Yang Oncotarget 6 (4), 2466, 2015 | 171 | 2015 |
Cumulative burden of colorectal cancer–associated genetic variants is more strongly associated with early-onset vs late-onset cancer AN Archambault, YR Su, J Jeon, M Thomas, Y Lin, DV Conti, AK Win, ... Gastroenterology 158 (5), 1274-1286. e12, 2020 | 143 | 2020 |
Genomic amplification and a role in drug-resistance for the KDM5A histone demethylase in breast cancer J Hou, J Wu, A Dombkowski, K Zhang, A Holowatyj, JL Boerner, ZQ Yang American journal of translational research 4 (3), 247, 2012 | 136 | 2012 |
Racial/ethnic disparities in survival among patients with young-onset colorectal cancer AN Holowatyj, JJ Ruterbusch, LS Rozek, ML Cote, EM Stoffel Journal of Clinical Oncology 34 (18), 2148, 2016 | 133 | 2016 |
Energy balance and gastrointestinal cancer: risk, interventions, outcomes and mechanisms CM Ulrich, C Himbert, AN Holowatyj, SD Hursting Nature reviews Gastroenterology & hepatology 15 (11), 683-698, 2018 | 90 | 2018 |
A comprehensive framework for early-onset colorectal cancer research C Eng, AA Jacome, R Agarwal, MH Hayat, MX Byndloss, AN Holowatyj, ... The Lancet Oncology 23 (3), e116-e128, 2022 | 75 | 2022 |
An SH3PX1-dependent endocytosis-autophagy network restrains intestinal stem cell proliferation by counteracting EGFR-ERK signaling P Zhang, AN Holowatyj, T Roy, SM Pronovost, M Marchetti, H Liu, ... Developmental cell 49 (4), 574-589. e5, 2019 | 63 | 2019 |
Genetic alterations of KDM4 subfamily and therapeutic effect of novel demethylase inhibitor in breast cancer Q Ye, A Holowatyj, J Wu, H Liu, L Zhang, T Suzuki, ZQ Yang American journal of cancer research 5 (4), 1519, 2015 | 62 | 2015 |
Distinct molecular phenotype of sporadic colorectal cancers among young patients based on multiomics analysis AN Holowatyj, B Gigic, E Herpel, A Scalbert, M Schneider, CM Ulrich, ... Gastroenterology 158 (4), 1155-1158. e2, 2020 | 52 | 2020 |
Plasma metabolites associated with colorectal cancer: a discovery‐replication strategy AJMR Geijsen, S Brezina, P Keski‐Rahkonen, A Baierl, ... International journal of cancer 145 (5), 1221-1231, 2019 | 49 | 2019 |
Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer H Liu, L Liu, A Holowatyj, Y Jiang, ZQ Yang Molecular carcinogenesis 55 (5), 977-990, 2016 | 45 | 2016 |
Examining factors underlying geographic disparities in early-onset colorectal cancer survival among men in the United States CR Rogers, JX Moore, F Qeadan, LY Gu, MS Huntington, AN Holowatyj American journal of cancer research 10 (5), 1592, 2020 | 40 | 2020 |
Clinicopathologic and racial/ethnic differences of colorectal cancer among adolescents and young adults AN Holowatyj, MA Lewis, ST Pannier, AC Kirchhoff, S Hardikar, ... Clinical and translational gastroenterology 10 (7), e00059, 2019 | 38 | 2019 |
Plasma metabolites associated with colorectal cancer stage: Findings from an international consortium AJMR Geijsen, EH van Roekel, FJB van Duijnhoven, D Achaintre, ... International journal of cancer 146 (12), 3256-3266, 2020 | 32 | 2020 |
Body fatness, adipose tissue compartments, and biomarkers of inflammation and angiogenesis in colorectal cancer: the ColoCare study C Himbert, J Ose, J Nattenmüller, CA Warby, AN Holowatyj, J Böhm, T Lin, ... Cancer Epidemiology, Biomarkers & Prevention 28 (1), 76-82, 2019 | 32 | 2019 |
Histone demethylase GASC1, a potential prognostic and predictive marker in esophageal squamous cell carcinoma LL Sun, A Holowatyj, XE Xu, JY Wu, ZY Wu, JH Shen, SH Wang, EM Li, ... American journal of cancer research 3 (5), 509, 2013 | 29 | 2013 |
The epidemiology of cancer among homeless adults in metropolitan Detroit AN Holowatyj, EI Heath, LM Pappas, JJ Ruterbusch, DH Gorski, JA Triest, ... JNCI Cancer Spectrum 3 (1), pkz006, 2019 | 27 | 2019 |
Gut instinct: a call to study the biology of early-onset colorectal cancer disparities AN Holowatyj, J Perea, CH Lieu Nature Reviews Cancer 21 (6), 339-340, 2021 | 25 | 2021 |
HER 2 status and disparities in luminal breast cancers AN Holowatyj, JJ Ruterbusch, M Ratnam, DH Gorski, ML Cote Cancer Medicine 5 (8), 2109-2116, 2016 | 25 | 2016 |