Regulation of cellular metabolism by protein lysine acetylation S Zhao, W Xu, W Jiang, W Yu, Y Lin, T Zhang, J Yao, L Zhou, Y Zeng, H Li, ... Science 327 (5968), 1000-1004, 2010 | 2076 | 2010 |
An expanded eukaryotic genetic code JW Chin, TA Cropp, JC Anderson, M Mukherji, Z Zhang, PG Schultz Science 301 (5635), 964-967, 2003 | 1128 | 2003 |
Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins K Lang, JW Chin Chemical reviews 114 (9), 4764-4806, 2014 | 1125 | 2014 |
Addition of p-Azido-l-phenylalanine to the Genetic Code of Escherichia c oli JW Chin, SW Santoro, AB Martin, DS King, L Wang, PG Schultz Journal of the American Chemical Society 124 (31), 9026-9027, 2002 | 1060 | 2002 |
Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli JW Chin, AB Martin, DS King, L Wang, PG Schultz Proceedings of the National Academy of Sciences 99 (17), 11020-11024, 2002 | 993 | 2002 |
Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome H Neumann, K Wang, L Davis, M Garcia-Alai, JW Chin Nature 464 (7287), 441-444, 2010 | 752 | 2010 |
Genetically encoding Nε-acetyllysine in recombinant proteins H Neumann, SY Peak-Chew, JW Chin Nature chemical biology 4 (4), 232-234, 2008 | 720 | 2008 |
Expanding and reprogramming the genetic code JW Chin Nature 550 (7674), 53-60, 2017 | 674 | 2017 |
Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae A Deiters, TA Cropp, M Mukherji, JW Chin, JC Anderson, PG Schultz Journal of the American Chemical Society 125 (39), 11782-11783, 2003 | 646 | 2003 |
Bioorthogonal reactions for labeling proteins K Lang, JW Chin ACS chemical biology 9 (1), 16-20, 2014 | 619 | 2014 |
Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels … K Lang, L Davis, S Wallace, M Mahesh, DJ Cox, ML Blackman, JM Fox, ... Journal of the American Chemical Society 134 (25), 10317-10320, 2012 | 599 | 2012 |
A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation H Neumann, SM Hancock, R Buning, A Routh, L Chapman, J Somers, ... Molecular cell 36 (1), 153-163, 2009 | 575 | 2009 |
Expanding and reprogramming the genetic code of cells and animals JW Chin Annual review of biochemistry 83, 379-408, 2014 | 547 | 2014 |
Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction K Lang, L Davis, J Torres-Kolbus, C Chou, A Deiters, JW Chin Nature chemistry 4 (4), 298-304, 2012 | 537 | 2012 |
Total synthesis of Escherichia coli with a recoded genome J Fredens, K Wang, D de la Torre, LFH Funke, WE Robertson, Y Christova, ... Nature 569 (7757), 514-518, 2019 | 490 | 2019 |
In vivo incorporation of unnatural amino acids P Schultz, L Wang, JC Anderson, JW Chin, DR Liu, TJ Magliery, ... US Patent 7,045,337, 2006 | 442 | 2006 |
Designer proteins: applications of genetic code expansion in cell biology L Davis, JW Chin Nature reviews Molecular cell biology 13 (3), 168-182, 2012 | 413 | 2012 |
A network of orthogonal ribosome· mRNA pairs O Rackham, JW Chin Nature chemical biology 1 (3), 159-166, 2005 | 409 | 2005 |
Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteins via a Pyrrolysyl-tRNA Synthetase/tRNACUA Pair and Click Chemistry DP Nguyen, H Lusic, H Neumann, PB Kapadnis, A Deiters, JW Chin Journal of the American Chemical Society 131 (25), 8720-8721, 2009 | 400 | 2009 |
Evolved orthogonal ribosomes enhance the efficiency of synthetic genetic code expansion K Wang, H Neumann, SY Peak-Chew, JW Chin Nature biotechnology 25 (7), 770-777, 2007 | 396 | 2007 |