Oxidized phospholipids trigger atherogenic inflammation in murine arteries A Furnkranz, A Schober, VN Bochkov, P Bashtrykov, G Kronke, A Kadl, ... Arteriosclerosis, thrombosis, and vascular biology 25 (3), 633-638, 2005 | 203 | 2005 |
The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism P Bashtrykov, G Jankevicius, RZ Jurkowska, S Ragozin, A Jeltsch Journal of Biological Chemistry 289 (7), 4106-4115, 2014 | 140 | 2014 |
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms L Gao, M Emperle, Y Guo, SA Grimm, W Ren, S Adam, H Uryu, ZM Zhang, ... Nature communications 11 (1), 1-14, 2020 | 130 | 2020 |
Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain P Bashtrykov, G Jankevicius, A Smarandache, RZ Jurkowska, S Ragozin, ... Chemistry & biology 19 (5), 572-578, 2012 | 117 | 2012 |
Expression of adhesion molecule T-cadherin is increased during neointima formation in experimental restenosis E Kudrjashova, P Bashtrikov, V Bochkov, Y Parfyonova, V Tkachuk, ... Histochemistry and cell biology 118, 281-290, 2002 | 109 | 2002 |
Urokinase plasminogen activator stimulates vascular smooth muscle cell proliferation via redox-dependent pathways M Menshikov, O Plekhanova, H Cai, K Chalupsky, Y Parfyonova, ... Arteriosclerosis, thrombosis, and vascular biology 26 (4), 801-807, 2006 | 98 | 2006 |
H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1 RZ Jurkowska, S Qin, G Kungulovski, W Tempel, Y Liu, P Bashtrykov, ... Nature communications 8 (1), 2057, 2017 | 77 | 2017 |
Molecular processes connecting DNA methylation patterns with DNA methyltransferases and histone modifications in mammalian genomes A Jeltsch, J Broche, P Bashtrykov Genes 9 (11), 566, 2018 | 72 | 2018 |
Identification of novel inhibitors of DNA methylation by screening of a chemical library A Ceccaldi, A Rajavelu, S Ragozin, C Sénamaud-Beaufort, P Bashtrykov, ... ACS chemical biology 8 (3), 543-548, 2013 | 68 | 2013 |
Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns M Emperle, S Adam, S Kunert, M Dukatz, A Baude, C Plass, P Rathert, ... Nucleic acids research 47 (21), 11355-11367, 2019 | 62 | 2019 |
DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation S Adam, H Anteneh, M Hornisch, V Wagner, J Lu, NE Radde, ... Nature communications 11 (1), 3723, 2020 | 61 | 2020 |
H3K36me2/3 binding and DNA binding of the DNA methyltransferase DNMT3A PWWP domain both contribute to its chromatin interaction M Dukatz, K Holzer, M Choudalakis, M Emperle, C Lungu, P Bashtrykov, ... Journal of molecular biology 431 (24), 5063-5074, 2019 | 56 | 2019 |
Cocaine-induced chromatin modifications associate with increased expression and three-dimensional looping of Auts2 O Engmann, B Labonté, A Mitchell, P Bashtrykov, ES Calipari, ... Biological psychiatry 82 (11), 794-805, 2017 | 45 | 2017 |
Engineering of effector domains for targeted DNA methylation with reduced off-target effects D Hofacker, J Broche, L Laistner, S Adam, P Bashtrykov, A Jeltsch International journal of molecular sciences 21 (2), 502, 2020 | 41 | 2020 |
Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain P Bashtrykov, A Rajavelu, B Hackner, S Ragozin, T Carell, A Jeltsch Chembiochem 15 (5), 743-748, 2014 | 41 | 2014 |
Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase P Bashtrykov, S Ragozin, A Jeltsch FEBS letters 586 (13), 1821-1823, 2012 | 33 | 2012 |
Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase M Dukatz, S Adam, M Biswal, J Song, P Bashtrykov, A Jeltsch Nucleic acids research 48 (20), 11495-11509, 2020 | 28 | 2020 |
DNMT1-associated DNA methylation changes in cancer P Bashtrykov, A Jeltsch Cell Cycle 14 (1), 5-5, 2015 | 28 | 2015 |
Deep enzymology studies on DNA methyltransferases reveal novel connections between flanking sequences and enzyme activity A Jeltsch, S Adam, M Dukatz, M Emperle, P Bashtrykov Journal of molecular biology 433 (19), 167186, 2021 | 24 | 2021 |
Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing J Broche, G Kungulovski, P Bashtrykov, P Rathert, A Jeltsch Nucleic acids research 49 (1), 158-176, 2021 | 24 | 2021 |