Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial PD Monk, RJ Marsden, VJ Tear, J Brookes, TN Batten, M Mankowski, ... The Lancet Respiratory Medicine 9 (2), 196-206, 2021 | 473 | 2021 |
SP-A and SP-D: dual functioning immune molecules with antiviral and immunomodulatory properties A Watson, J Madsen, H Clark Frontiers in Immunology, 2021 | 112 | 2021 |
COVID-19: time for a bold new strategy for medical education A Watson, T McKinnon, SD Prior, L Richards, CA Green Medical Education Online 25 (1), 1764741, 2020 | 68 | 2020 |
Dynamics of IFN-β responses during respiratory viral infection. Insights for therapeutic strategies A Watson, CM Spalluto, C McCrae, D Cellura, H Burke, D Cunoosamy, ... American journal of respiratory and critical care medicine 201 (1), 83-94, 2020 | 68 | 2020 |
Respiratory viral infections in the elderly A Watson, TMA Wilkinson Therapeutic advances in respiratory disease 15, 1753466621995050, 2021 | 59 | 2021 |
Surfactant proteins A and D: trimerized innate immunity proteins with an affinity for viral fusion proteins A Watson, MJS Phipps, HW Clark, CK Skylaris, J Madsen Journal of innate immunity 11 (1), 13-28, 2018 | 58 | 2018 |
A randomised controlled feasibility trial of E-health application supported care vs usual care after exacerbation of COPD: the RESCUE trial M North, S Bourne, B Green, AJ Chauhan, T Brown, J Winter, T Jones, ... NPJ digital medicine 3 (1), 145, 2020 | 51* | 2020 |
Digital healthcare in COPD management: a narrative review on the advantages, pitfalls, and need for further research A Watson, TMA Wilkinson Therapeutic Advances in Respiratory Disease 16, 17534666221075493, 2022 | 45 | 2022 |
The Role of Non-Typeable Haemophilus influenzae Biofilms in Chronic Obstructive Pulmonary Disease JR Weeks, KJ Staples, CM Spalluto, A Watson, TMA Wilkinson Frontiers in cellular and infection microbiology 11, 720742, 2021 | 40 | 2021 |
Evidence generation for the clinical impact of myCOPD in patients with mild, moderate and newly diagnosed COPD: a randomised controlled trial MG Crooks, J Elkes, W Storrar, K Roy, M North, A Blythin, A Watson, ... ERJ open research 6 (4), 2020 | 34 | 2020 |
Interrelationships among small airways dysfunction, neutrophilic inflammation, and exacerbation frequency in COPD K Day, K Ostridge, J Conway, D Cellura, A Watson, CM Spalluto, ... Chest 159 (4), 1391-1399, 2021 | 33 | 2021 |
Novel expression of a functional trimeric fragment of human SP-A with efficacy in neutralisation of RSV A Watson, N Kronqvist, CM Spalluto, M Griffiths, KJ Staples, T Wilkinson, ... Immunobiology 222 (2), 111-118, 2017 | 33 | 2017 |
Influence of hypoxia on the epithelial-pathogen interactions in the lung: implications for respiratory disease LK Page, KJ Staples, CM Spalluto, A Watson, TMA Wilkinson Frontiers in Immunology 12, 653969, 2021 | 32 | 2021 |
Protective effects of surfactant protein D treatment in 1, 3-β-glucan-modulated allergic inflammation D Fakih, B Pilecki, A Schlosser, CS Jepsen, LK Thomsen, M Ormhøj, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015 | 27 | 2015 |
Dysregulation of COVID-19 related gene expression in the COPD lung A Watson, L Öberg, B Angermann, CM Spalluto, M Hühn, H Burke, ... Respiratory research 22 (1), 164, 2021 | 26 | 2021 |
Patient perceived barriers to exercise and their clinical associations in difficult asthma AT Freeman, D Hill, C Newell, H Moyses, A Azim, D Knight, L Presland, ... Asthma research and practice 6, 1-11, 2020 | 21 | 2020 |
Surfactant protein a impairs genital HPV16 pseudovirus infection by innate immune cell activation in a murine model S Ujma, S Carse, A Chetty, W Horsnell, H Clark, J Madsen, RM Mackay, ... Pathogens 8 (4), 288, 2019 | 20 | 2019 |
Structural definition of hSP-D recognition of Salmonella enterica LPS inner core oligosaccharides reveals alternative binding modes for the same LPS JR Littlejohn, RF da Silva, WA Neale, CC Smallcombe, HW Clark, ... PLoS One 13 (6), e0199175, 2018 | 20 | 2018 |
Generation of novel trimeric fragments of human SP-A and SP-D after recombinant soluble expression in E. coli A Watson, GL Sørensen, U Holmskov, HJ Whitwell, J Madsen, H Clark Immunobiology 225 (4), 151953, 2020 | 18 | 2020 |
Wave comparisons of clinical characteristics and outcomes of COVID-19 admissions-Exploring the impact of treatment and strain dynamics A Freeman, A Watson, P O'Regan, O Wysocki, H Burke, A Freitas, ... Journal of Clinical Virology 146, 105031, 2022 | 15 | 2022 |