Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ... Nature genetics 49 (10), 1421-1427, 2017 | 439 | 2017 |
Trans effects on gene expression can drive omnigenic inheritance X Liu, YI Li, JK Pritchard Cell 177 (4), 1022-1034. e6, 2019 | 348 | 2019 |
Deep whole-genome sequencing of 100 southeast Asian Malays LP Wong, RTH Ong, WT Poh, X Liu, P Chen, R Li, KKY Lam, NE Pillai, ... The American Journal of Human Genetics 92 (1), 52-66, 2013 | 200 | 2013 |
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits F Hormozdiari, S Gazal, B Van De Geijn, HK Finucane, CJT Ju, PR Loh, ... Nature genetics 50 (7), 1041-1047, 2018 | 166 | 2018 |
Detecting and characterizing genomic signatures of positive selection in global populations X Liu, RTH Ong, EN Pillai, AM Elzein, KS Small, TG Clark, ... The American Journal of Human Genetics 92 (6), 866-881, 2013 | 89 | 2013 |
Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues X Liu, HK Finucane, A Gusev, G Bhatia, S Gazal, LO Connor, ... Americal Journal of Human Genetics 100 (4), 605-616, 2017 | 82 | 2017 |
Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies X Wang, HX Chua, P Chen, RTH Ong, X Sim, W Zhang, F Takeuchi, X Liu, ... Human molecular genetics 22 (11), 2303-2311, 2013 | 78 | 2013 |
Insights into the genetic structure and diversity of 38 South Asian Indians from deep whole-genome sequencing LP Wong, JKH Lai, WY Saw, RTH Ong, AY Cheng, NE Pillai, X Liu, W Xu, ... PLoS genetics 10 (5), e1004377, 2014 | 51 | 2014 |
Detecting signatures of positive selection associated with musical aptitude in the human genome X Liu, C Kanduri, J Oikkonen, K Karma, P Raijas, L Ukkola-Vuoti, YY Teo, ... Scientific Reports 6, 2016 | 42 | 2016 |
Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees G Jun, A Manning, M Almeida, M Zawistowski, AR Wood, TM Teslovich, ... Proceedings of the National Academy of Sciences 115 (2), 379-384, 2018 | 41 | 2018 |
The fine-scale genetic structure and evolution of the Japanese population F Takeuchi, T Katsuya, R Kimura, T Nabika, M Isomura, T Ohkubo, ... PloS one 12 (11), e0185487, 2017 | 38 | 2017 |
Characterizing the genetic differences between two distinct migrant groups from Indo-European and Dravidian speaking populations in India M Ali, X Liu, EN Pillai, P Chen, CC Khor, RTH Ong, YY Teo BMC genetics 15, 1-11, 2014 | 35 | 2014 |
Characterising private and shared signatures of positive selection in 37 Asian populations X Liu, D Lu, WY Saw, PJ Shaw, P Wangkumhang, C Ngamphiw, ... European Journal of Human Genetics 25 (4), 499-508, 2017 | 28 | 2017 |
Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping R Twee-Hee Ong, X Wang, X Liu, YY Teo European journal of human genetics 20 (12), 1300-1307, 2012 | 27 | 2012 |
Differential positive selection of malaria resistance genes in three indigenous populations of Peninsular Malaysia X Liu, Y Yunus, D Lu, F Aghakhanian, WY Saw, L Deng, M Ali, X Wang, ... Human genetics 134, 375-392, 2015 | 26 | 2015 |
A statistical method for region-based meta-analysis of genome-wide association studies in genetically diverse populations X Wang, X Liu, X Sim, H Xu, CC Khor, RTH Ong, WT Tay, C Suo, WT Poh, ... European journal of human genetics 20 (4), 469-475, 2012 | 23 | 2012 |
Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability B van de Geijn, H Finucane, S Gazal, F Hormozdiari, T Amariuta, X Liu, ... Human molecular genetics 29 (7), 1057-1067, 2020 | 21 | 2020 |
Can evidence from genome-wide association studies and positive natural selection surveys be used to evaluate the thrifty gene hypothesis in East Asians? XH Koh, X Liu, YY Teo PLoS One 9 (10), e110974, 2014 | 21 | 2014 |
Pharmacogenomic diversity in Singaporean populations and Europeans LR Brunham, SL Chan, R Li, F Aminkeng, X Liu, WY Saw, RTH Ong, ... The pharmacogenomics journal 14 (6), 555-563, 2014 | 17 | 2014 |
Estimating the proportion of disease heritability mediated by gene expression levels LJ O’Connor, A Gusev, X Liu, PR Loh, HK Finucane, AL Price BioRxiv, 118018, 2017 | 13 | 2017 |