Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting N Fili, V Calleja, R Woscholski, PJ Parker, B Larijani Proceedings of the National Academy of Sciences 103 (42), 15473-15478, 2006 | 118 | 2006 |
NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription N Fili, Y Hari-Gupta, Á Dos Santos, A Cook, S Poland, SM Ameer-Beg, ... Nature Communications 8 (1), 1871, 2017 | 65 | 2017 |
Visualizing helicases unwinding DNA at the single molecule level N Fili, GI Mashanov, CP Toseland, C Batters, MI Wallace, JTP Yeeles, ... Nucleic acids research 38 (13), 4448-4457, 2010 | 63 | 2010 |
Atomic Force Microscopy micro-rheology reveals large structural inhomogeneities in single cell-nuclei M Lherbette, Á Dos Santos, Y Hari-Gupta, N Fili, CP Toseland, ... Scientific reports 7 (1), 8116, 2017 | 54 | 2017 |
Unconventional myosins: how regulation meets function N Fili, CP Toseland International journal of molecular sciences 21 (1), 67, 2019 | 53 | 2019 |
Monomeric PcrA helicase processively unwinds plasmid lengths of DNA in the presence of the initiator protein RepD LT Chisty, CP Toseland, N Fili, GI Mashanov, MS Dillingham, JE Molloy, ... Nucleic acids research 41 (9), 5010-5023, 2013 | 44 | 2013 |
Competition between two high-and low-affinity protein-binding sites in myosin VI controls its cellular function N Fili, Y Hari-Gupta, B Aston, Á Dos Santos, RE Gough, B Alamad, ... Journal of Biological Chemistry 295 (2), 337-347, 2020 | 25 | 2020 |
Myosin VI regulates the spatial organisation of mammalian transcription initiation Y Hari-Gupta, N Fili, Á Dos Santos, AW Cook, RE Gough, HCW Reed, ... Nature communications 13 (1), 1346, 2022 | 20 | 2022 |
Fluorescence and labelling: how to choose and what to do N Fili, CP Toseland Fluorescent methods for molecular motors, 1-24, 2014 | 18 | 2014 |
Nuclear myosin VI regulates the spatial organization of mammalian transcription initiation Y Hari-Gupta, N Fili, Á dos Santos, AW Cook, RE Gough, HCW Reed, ... bioRxiv, 2020.04. 21.053124, 2020 | 17 | 2020 |
Myosin VI moves on nuclear actin filaments and supports long-range chromatin rearrangements A Große-Berkenbusch, J Hettich, T Kuhn, N Fili, AW Cook, Y Hari-Gupta, ... Biorxiv, 2020.04. 03.023614, 2020 | 17 | 2020 |
Binding partners regulate unfolding of myosin VI to activate the molecular motor Á Dos Santos, N Fili, Y Hari-Gupta, RE Gough, L Wang, ... Biochemical Journal 479 (13), 1409-1428, 2022 | 12 | 2022 |
A single-molecule approach to visualize the unwinding activity of DNA helicases N Fili, CP Toseland, MS Dillingham, MR Webb, JE Molloy Single Molecule Enzymology: Methods and Protocols, 193-214, 2011 | 10 | 2011 |
High-throughput mechanobiology: Force modulation of ensemble biochemical and cell-based assays Á Dos Santos, N Fili, DS Pearson, Y Hari-Gupta, CP Toseland Biophysical Journal 120 (4), 631-641, 2021 | 9 | 2021 |
Occupational exposure to CO concentrations in enclosed garages: Estimation of blood COHb levels A Chaloulakou, N Fili, N Spyrelis Environmental Pollution, Proceedings of the 5th International Conference …, 2000 | 8 | 2000 |
NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription. Nat Commun 8 (1): 1871 N Fili, Y Hari-Gupta, A Dos Santos, A Cook, S Poland, SM Ameer-Beg, ... | 7 | 2017 |
Fluorescent methods for molecular motors CP Toseland, N Fili Springer, 2014 | 5 | 2014 |
Visualizing DNA unwinding by helicases at the single molecule level N Fili, G Mashanov, CP Toseland, C Batters, MI Wallace, JTP Yeeles, ... Nucleic Acids Res 38, 4448-4457, 2010 | 4 | 2010 |
A targeted and tuneable dna damage tool using crispr/cas9 I Emmanouilidis, N Fili, AW Cook, Y Hari-Gupta, Á Dos Santos, L Wang, ... Biomolecules 11 (2), 288, 2021 | 3 | 2021 |
Single-molecule and single-particle imaging of molecular motors in vitro and in vivo N Fili Fluorescent Methods for Molecular Motors, 131-159, 2014 | 3 | 2014 |