| Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide AK Shukla, A Manglik, AC Kruse, K Xiao, RI Reis, WC Tseng, DP Staus, ... Nature 497 (7447), 137-141, 2013 | 465 | 2013 |
| Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ... Nature 535 (7612), 448-452, 2016 | 326 | 2016 |
| Structure of the M2 muscarinic receptor–β-arrestin complex in a lipid nanodisc DP Staus, H Hu, MJ Robertson, ALW Kleinhenz, LM Wingler, WD Capel, ... Nature 579 (7798), 297-302, 2020 | 273 | 2020 |
| Multidimensional tracking of GPCR signaling via peroxidase-catalyzed proximity labeling J Paek, M Kalocsay, DP Staus, L Wingler, R Pascolutti, JA Paulo, SP Gygi, ... Cell 169 (2), 338-349. e11, 2017 | 252 | 2017 |
| Angiotensin analogs with divergent bias stabilize distinct receptor conformations LM Wingler, M Elgeti, D Hilger, NR Latorraca, MT Lerch, DP Staus, ... Cell 176 (3), 468-478. e11, 2019 | 230 | 2019 |
| Molecular mechanism of biased signaling in a prototypical G-protein-coupled receptor CM Suomivuori, NR Latorraca, LM Wingler, S Eismann, MC King, ... Biophysical Journal 118 (3), 162a, 2020 | 184 | 2020 |
| Distinctive activation mechanism for angiotensin receptor revealed by a synthetic nanobody LM Wingler, C McMahon, DP Staus, RJ Lefkowitz, AC Kruse Cell 176 (3), 479-490. e12, 2019 | 170 | 2019 |
| Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR LM Wingler, MA Skiba, C McMahon, DP Staus, ALW Kleinhenz, ... Science 367 (6480), 888-892, 2020 | 167 | 2020 |
| Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies DP Staus, LM Wingler, RT Strachan, SGF Rasmussen, E Pardon, S Ahn, ... Molecular pharmacology 85 (3), 472-481, 2014 | 148 | 2014 |
| Allosteric “beta-blocker” isolated from a DNA-encoded small molecule library S Ahn, AW Kahsai, B Pani, QT Wang, S Zhao, AL Wall, RT Strachan, ... Proceedings of the National Academy of Sciences 114 (7), 1708-1713, 2017 | 134 | 2017 |
| Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling J Wang, K Hanada, DP Staus, MA Makara, GR Dahal, Q Chen, A Ahles, ... Nature communications 8 (1), 1706, 2017 | 101 | 2017 |
| Mechanism of β2AR regulation by an intracellular positive allosteric modulator X Liu, A Masoudi, AW Kahsai, LY Huang, B Pani, DP Staus, PJ Shim, ... Science 364 (6447), 1283-1287, 2019 | 93 | 2019 |
| Noncanonical scaffolding of Gαi and β-arrestin by G protein–coupled receptors JS Smith, TF Pack, A Inoue, C Lee, K Zheng, I Choi, DS Eiger, A Warman, ... Science 371 (6534), eaay1833, 2021 | 86 | 2021 |
| Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor AW Kahsai, JW Wisler, J Lee, S Ahn, TJ Cahill III, SM Dennison, DP Staus, ... Nature chemical biology 12 (9), 709-716, 2016 | 78 | 2016 |
| Small-molecule positive allosteric modulators of the β2-adrenoceptor isolated from DNA-encoded libraries S Ahn, B Pani, AW Kahsai, EK Olsen, G Husemoen, M Vestergaard, L Jin, ... Molecular pharmacology 94 (2), 850-861, 2018 | 73 | 2018 |
| Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling DP Staus, LM Wingler, M Choi, B Pani, A Manglik, AC Kruse, RJ Lefkowitz Proceedings of the National Academy of Sciences 115 (15), 3834-3839, 2018 | 64 | 2018 |
| G protein–coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor M Choi, DP Staus, LM Wingler, S Ahn, B Pani, WD Capel, RJ Lefkowitz Science signaling 11 (544), eaar7084, 2018 | 63 | 2018 |
| Diaphanous 1 and 2 regulate smooth muscle cell differentiation by activating the myocardin-related transcription factors DP Staus, AL Blaker, JM Taylor, CP Mack Arteriosclerosis, thrombosis, and vascular biology 27 (3), 478-486, 2007 | 63 | 2007 |
| Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation MD Medlin, DP Staus, AD Dubash, JM Taylor, CP Mack Arteriosclerosis, thrombosis, and vascular biology 30 (9), 1779-1786, 2010 | 57 | 2010 |
| Detergent-and phospholipid-based reconstitution systems have differential effects on constitutive activity of G-protein–coupled receptors DP Staus, LM Wingler, D Pichugin, RS Prosser, RJ Lefkowitz Journal of Biological Chemistry 294 (36), 13218-13223, 2019 | 43 | 2019 |
