Sibling rivalry in the E2F family JM Trimarchi, JA Lees Nature reviews Molecular cell biology 3 (1), 11-20, 2002 | 1478 | 2002 |
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers GL Mutter, MC Lin, JT Fitzgerald, JB Kum, JPA Baak, JA Lees, LP Weng, ... Journal of the national cancer institute 92 (11), 924-930, 2000 | 1227 | 2000 |
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. PS Danielian, R White, JA Lees, MG Parker The EMBO journal 11 (3), 1025-1033, 1992 | 1048 | 1992 |
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F K Helin, JA Lees, M Vidal, N Dyson, E Harlow, A Fattaey Cell 70 (2), 337-350, 1992 | 830 | 1992 |
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor SE Fawell, JA Lees, R White, MG Parker Cell 60 (6), 953-962, 1990 | 771 | 1990 |
p53-deficient cells rely on ATM-and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage HC Reinhardt, AS Aslanian, JA Lees, MB Yaffe Cancer cell 11 (2), 175-189, 2007 | 737 | 2007 |
The retinoblastoma protein binds to a family of E2F transcription factors JA Lees, M Saito, M Vidal, M Valentine, T Look, E Harlow, N Dyson, ... Molecular and cellular biology, 1993 | 632 | 1993 |
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. K Helin, CL Wu, AR Fattaey, JA Lees, BD Dynlacht, C Ngwu, E Harlow Genes & development 7 (10), 1850-1861, 1993 | 614 | 1993 |
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast A Perren, LP Weng, AH Boag, U Ziebold, K Thakore, PLM Dahia, ... The American journal of pathology 155 (4), 1253-1260, 1999 | 538 | 1999 |
Differential regulation of E2F transactivation by cyclin/cdk2 complexes. BD Dynlacht, O Flores, JA Lees, E Harlow Genes & development 8 (15), 1772-1786, 1994 | 538 | 1994 |
Many ribosomal protein genes are cancer genes in zebrafish A Amsterdam, KC Sadler, K Lai, S Farrington, RT Bronson, JA Lees, ... PLoS biology 2 (5), e139, 2004 | 512 | 2004 |
E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry K Moberg, MA Starz, JA Lees Molecular and cellular biology, 1996 | 468 | 1996 |
Structural organization and expression of the mouse estrogen receptor R White, JA Lees, M Needham, J Ham, M Parker Molecular Endocrinology 1 (10), 735-744, 1987 | 450 | 1987 |
E2f3 is critical for normal cellular proliferation PO Humbert, R Verona, JM Trimarchi, C Rogers, S Dandapani, JA Lees Genes & development 14 (6), 690-703, 2000 | 437 | 2000 |
Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors O Gimm, A Perren, LP Weng, DJ Marsh, JJ Yeh, U Ziebold, E Gil, R Hinze, ... The American journal of pathology 156 (5), 1693-1700, 2000 | 427 | 2000 |
The retinoblastoma protein is phosphorylated on multiple sites by human cdc2. JA Lees, KJ Buchkovich, DR Marshak, CW Anderson, E Harlow The EMBO journal 10 (13), 4279-4290, 1991 | 421 | 1991 |
Single-molecule transcript counting of stem-cell markers in the mouse intestine S Itzkovitz, A Lyubimova, IC Blat, M Maynard, J Van Es, J Lees, T Jacks, ... Nature cell biology 14 (1), 106-114, 2012 | 396 | 2012 |
Identification of two transactlvation domains in the mouse oestrogen receptor JA Lees, SE Fawell, MG Parker Nucleic acids research 17 (14), 5477-5488, 1989 | 395 | 1989 |
PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death LP Weng, WM Smith, PLM Dahia, U Ziebold, E Gil, JA Lees, C Eng Cancer research 59 (22), 5808-5814, 1999 | 382 | 1999 |
E2Fs regulate adipocyte differentiation L Fajas, RL Landsberg, Y Huss-Garcia, C Sardet, JA Lees, J Auwerx Developmental cell 3 (1), 39-49, 2002 | 374 | 2002 |