Stimulating Macropinocytosis for Intracellular Nucleic Acid and Protein Delivery: A Combined Strategy with Membrane-Lytic Peptides To Facilitate Endosomal Escape JVV Arafiles, H Hirose, M Akishiba, S Tsuji, M Imanishi, S Futaki Bioconjugate Chemistry 31 (3), 547-553, 2020 | 41 | 2020 |
Liquid droplet formation and facile cytosolic translocation of IgG in the presence of attenuated cationic amphiphilic lytic peptides T Iwata, H Hirose, K Sakamoto, Y Hirai, JVV Arafiles, M Akishiba, ... Angewandte Chemie International Edition 60 (36), 19804-19812, 2021 | 30 | 2021 |
Peptide-Assisted Intracellular Delivery of Biomacromolecules S Futaki, JVV Arafiles, H Hirose Chemistry Letters 49 (9), 1088-1094, 2020 | 28 | 2020 |
Structure–Uptake Relationship Study of DABCYL Derivatives Linked to Cyclic Cell‐Penetrating Peptides for Live‐Cell Delivery of Synthetic Proteins A Saha, S Mandal, JVV Arafiles, J Gómez‐González, CPR Hackenberger, ... Angewandte Chemie International Edition 61 (47), e202207551, 2022 | 17 | 2022 |
Artificial nanocage formed via self-assembly of β-annulus peptide for delivering biofunctional proteins into cell interiors K Sakamoto, H Furukawa, JVV Arafiles, M Imanishi, K Matsuura, S Futaki Bioconjugate Chemistry 33 (2), 311-320, 2022 | 16 | 2022 |
Enhancing the activity of membrane remodeling epsin-peptide by trimerization WY Hsu, T Masuda, S Afonin, T Sakai, JVV Arafiles, K Kawano, H Hirose, ... Bioorganic & Medicinal Chemistry Letters 30 (12), 127190, 2020 | 15 | 2020 |
A facile combinatorial approach to construct a ratiometric fluorescent sensor: application for the real-time sensing of cellular pH changes E Nakata, H Hirose, K Gerelbaatar, JVV Arafiles, Z Zhang, S Futaki, ... Chemical Science 12 (23), 8231-8240, 2021 | 13 | 2021 |
Discovery of a Macropinocytosis‐Inducing Peptide Potentiated by Medium‐Mediated Intramolecular Disulfide Formation JVV Arafiles, H Hirose, Y Hirai, M Kuriyama, MM Sakyiamah, W Nomura, ... Angewandte Chemie 133 (21), 12035-12043, 2021 | 12 | 2021 |
Piezo1 activation using Yoda1 inhibits macropinocytosis in A431 human epidermoid carcinoma cells M Kuriyama, H Hirose, T Masuda, M Shudou, JVV Arafiles, M Imanishi, ... Scientific reports 12 (1), 6322, 2022 | 11 | 2022 |
Stearylated macropinocytosis-inducing peptides facilitating the cellular uptake of small extracellular vesicles Y Nakagawa, JVV Arafiles, Y Kawaguchi, I Nakase, H Hirose, S Futaki Bioconjugate Chemistry 33 (5), 869-880, 2022 | 10 | 2022 |
Cell-surface-retained peptide additives for the cytosolic delivery of functional proteins JVV Arafiles, J Franke, L Franz, J Gómez-González, K Kemnitz-Hassanin, ... Journal of the American Chemical Society 145 (45), 24535-24548, 2023 | 6 | 2023 |
Use of homoarginine to obtain attenuated cationic membrane lytic peptides K Sakamoto, M Akishiba, T Iwata, JVV Arafiles, M Imanishi, S Futaki Bioorganic & Medicinal Chemistry Letters 40, 127925, 2021 | 6 | 2021 |
Chemical passports to cross biological borders JVV Arafiles, S Futaki Nature Chemistry 13 (6), 517-519, 2021 | 5 | 2021 |
L17ER4: A cell-permeable attenuated cationic amphiphilic lytic peptide K Shinga, T Iwata, K Murata, Y Daitoku, J Michibata, JVV Arafiles, ... Bioorganic & Medicinal Chemistry 61, 116728, 2022 | 4 | 2022 |
Grafting Hydrophobic Amino Acids Critical for Inhibition of Protein–Protein Interactions on a Cell-Penetrating Peptide Scaffold Y Nagano, JVV Arafiles, K Kuwata, Y Kawaguchi, M Imanishi, H Hirose, ... Molecular Pharmaceutics 19 (2), 558-567, 2021 | 3 | 2021 |
Struktur‐Wirkungsbeziehung von an zyklische Zell‐penetrierende Peptide gebundenen DABCYL‐Derivaten für den Transport von synthetischen Proteinen in lebende Zellen A Saha, S Mandal, JVV Arafiles, J Gómez‐González, CPR Hackenberger, ... Angewandte Chemie 134 (47), e202207551, 2022 | 2 | 2022 |
Modular solid-phase synthesis of electrophilic cysteine-selective ethynyl-phosphonamidate peptides S Hansen, JVV Arafiles, P Ochtrop, CPR Hackenberger Chemical Communications 58 (60), 8388-8391, 2022 | 2 | 2022 |
Piezo1 activation using Yoda1 inhibits macropinocytosis and proliferation of cancer cells M Kuriyama, H Hirose, T Masuda, M Shudou, JVV Arafiles, M Imanishi, ... bioRxiv, 2021.05. 14.444123, 2021 | 2 | 2021 |
Cover Picture: Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic Peptides (Angew. Chem. Int. Ed. 36/2021) T Iwata, H Hirose, K Sakamoto, Y Hirai, JVV Arafiles, M Akishiba, ... Angewandte Chemie International Edition 60 (36), 19493-19493, 2021 | 1 | 2021 |
Berichtigung: Struktur‐Wirkungsbeziehung von an zyklische Zell‐penetrierende Peptide gebundenen DABCYL‐Derivaten für den Transport von synthetischen Proteinen in lebende Zellen A Saha, S Mandal, JVV Arafiles, J Gómez‐González, CPR Hackenberger, ... Angewandte Chemie 135 (33), e202307870, 2023 | | 2023 |