T cell receptor (TCR) signaling in health and disease K Shah, A Al-Haidari, J Sun, JU Kazi Signal transduction and targeted therapy 6 (1), 412, 2021 | 250 | 2021 |
SYK is a critical regulator of FLT3 in acute myeloid leukemia A Puissant, N Fenouille, G Alexe, Y Pikman, CF Bassil, S Mehta, J Du, ... Cancer cell 25 (2), 226-242, 2014 | 153 | 2014 |
FMS-like tyrosine kinase 3/ FLT3: from basic science to clinical implications JU Kazi, L Rönnstrand Physiological Reviews 99 (3), 1433–1466, 2019 | 144 | 2019 |
Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML O Lindblad, E Cordero, A Puissant, L Macaulay, A Ramos, NN Kabir, ... Oncogene 35 (39), 5119-5131, 2016 | 117 | 2016 |
SOCS proteins in regulation of receptor tyrosine kinase signaling JU Kazi, NN Kabir, A Flores-Morales, L Rönnstrand Cellular and molecular life sciences 71, 3297-3310, 2014 | 111 | 2014 |
Machine learning in the prediction of cancer therapy R Rafique, SMR Islam, JU Kazi Computational and Structural Biotechnology Journal 19, 4003-4017, 2021 | 79 | 2021 |
Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3 JU Kazi, J Sun, B Phung, F Zadjali, A Flores-Morales, L Rönnstrand Journal of Biological Chemistry 287 (43), 36509-36517, 2012 | 75 | 2012 |
Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling JU Kazi, L Rönnstrand Molecular oncology 7 (3), 693-703, 2013 | 59 | 2013 |
Keratin 19 expression correlates with poor prognosis in breast cancer NN Kabir, L Rönnstrand, JU Kazi Molecular biology reports 41, 7729-7735, 2014 | 53 | 2014 |
Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis H Ke, JU Kazi, H Zhao, J Sun Cell & Bioscience 6, 1-10, 2016 | 50 | 2016 |
The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL) M Gazi, SA Moharram, A Marhäll, JU Kazi Cancer Letters 392, 9-16, 2017 | 48 | 2017 |
Celecoxib‐induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G JW Soh, JU Kazi, H Li, WJ Thompson, IB Weinstein Molecular Carcinogenesis: Published in cooperation with the University of …, 2008 | 48 | 2008 |
FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia JU Kazi, L Rönnstrand Molecular oncology 7 (3), 402-418, 2013 | 47 | 2013 |
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia A Hyrenius-Wittsten, M Pilheden, H Sturesson, J Hansson, MP Walsh, ... Nature Communications 9 (1), 1770, 2018 | 45 | 2018 |
Brain-Expressed X-linked (BEX) proteins in human cancers JU Kazi, NN Kabir, L Rönnstrand Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1856 (2), 226-233, 2015 | 45 | 2015 |
Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3 DC Lin, T Yin, M Koren-Michowitz, LW Ding, S Gueller, S Gery, ... Blood, The Journal of the American Society of Hematology 120 (16), 3310-3317, 2012 | 44 | 2012 |
The role of HOXB2 and HOXB3 in acute myeloid leukemia O Lindblad, RA Chougule, SA Moharram, NN Kabir, J Sun, JU Kazi, ... Biochemical and biophysical research communications 467 (4), 742-747, 2015 | 43 | 2015 |
SOCS6 is a selective suppressor of receptor tyrosine kinase signaling NN Kabir, J Sun, L Rönnstrand, JU Kazi Tumor Biology 35, 10581-10589, 2014 | 41 | 2014 |
Src-Like adaptor protein (SLAP) binds to the receptor tyrosine kinase Flt3 and modulates receptor stability and downstream signaling JU Kazi, L Rönnstrand PloS one 7 (12), e53509, 2012 | 40 | 2012 |
Isoform-specific translocation of PKC isoforms in NIH3T3 cells by TPA JU Kazi, JW Soh Biochemical and biophysical research communications 364 (2), 231-237, 2007 | 38 | 2007 |