KANK deficiency leads to podocyte dysfunction and nephrotic syndrome HY Gee, F Zhang, S Ashraf, S Kohl, CE Sadowski, V Vega-Warner, ... The Journal of clinical investigation 125 (6), 2375-2384, 2015 | 206 | 2015 |
APOL1-G1 in nephrocytes induces hypertrophy and accelerates cell death Y Fu, J Zhu, A Richman, Y Zhang, X Xie, JR Das, J Li, PE Ray, Z Han Journal of the American Society of Nephrology 28 (4), 1106-1116, 2017 | 79 | 2017 |
Epigenetic mechanisms underlying maternal diabetes-associated risk of congenital heart disease M Basu, JY Zhu, S LaHaye, U Majumdar, K Jiao, Z Han, V Garg JCI Insight 2 (20), 2017 | 71 | 2017 |
High throughput in vivo functional validation of candidate congenital heart disease genes in Drosophila J Zhu, Y Fu, M Nettleton, A Richman, Z Han Elife 6, e22617, 2017 | 56 | 2017 |
Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson’s disease model J Zhu, N Vereshchagina, V Sreekumar, LF Burbulla, AC Costa, KJ Daub, ... PloS one 8 (12), e83714, 2013 | 53 | 2013 |
A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome Y Fu, J Zhu, A Richman, Z Zhao, F Zhang, PE Ray, Z Han Human Molecular Genetics 26 (4), 768-780, 2017 | 38 | 2017 |
Comprehensive functional analysis of Rab GTPases in Drosophila nephrocytes Y Fu, J Zhu, F Zhang, A Richman, Z Zhao, Z Han Cell and Tissue Research 3 (368), 615-627, 2017 | 35 | 2017 |
Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism R Yu, X Cao, L Sun, J Zhu, BM Wasko, W Liu, E Crutcher, H Liu, MC Jo, ... Nature Communications 12 (1), 1981, 2021 | 34 | 2021 |
Mutations in NUP160 are implicated in steroid-resistant nephrotic syndrome F Zhao, J Zhu, A Richman, Y Fu, W Huang, N Chen, X Pan, C Yi, X Ding, ... Journal of the American Society of Nephrology 30 (5), 840-853, 2019 | 26 | 2019 |
Functional analysis of SARS-CoV-2 proteins in Drosophila identifies Orf6-induced pathogenic effects with Selinexor as an effective treatment J Zhu, JG Lee, J van de Leemput, H Lee, Z Han Cell & bioscience 11, 1-13, 2021 | 23 | 2021 |
The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1 J Zhu, A Heidersbach, IS Kathiriya, BI Garay, KN Ivey, D Srivastava, Z Han, ... Development 144 (5), 866-875, 2017 | 23 | 2017 |
A Personalized Model of COQ2 Nephropathy Rescued by the Wild-Type COQ2 Allele or Dietary Coenzyme Q10 Supplementation J Zhu, Y Fu, A Richman, Z Zhao, PE Ray, Z Han Journal of the American Society of Nephrology, ASN. 2016060626, 2017 | 18 | 2017 |
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis J Zhu, G Wang, X Huang, H Lee, JG Lee, P Yang, J van de Leemput, ... Communications biology 5 (1), 1039, 2022 | 16 | 2022 |
Gia/Mthl5 is an aorta specific GPCR required for Drosophila heart tube morphology and normal pericardial cell positioning MV Patel, J Zhu, Z Jiang, A Richman, MFA VanBerkum, Z Han Developmental biology 414 (1), 100-107, 2016 | 13 | 2016 |
Exocyst genes are essential for recycling membrane proteins and maintaining slit diaphragm in Drosophila nephrocytes P Wen, F Zhang, Y Fu, J Zhu, Z Han Journal of the American Society of Nephrology 31 (5), 1024-1034, 2020 | 12 | 2020 |
NMDA receptor‐gated visual responses in hippocampal CA1 neurons Y Liu, Y Wang, W Tang, J Zhu, Z Wang The Journal of physiology 596 (10), 1965-1979, 2018 | 12 | 2018 |
Wnt4 is required for ostia development in the Drosophila heart Z Chen, J Zhu, Y Fu, A Richman, Z Han Developmental biology 413 (2), 188-198, 2016 | 12 | 2016 |
Validating Candidate Congenital Heart Disease Genes in Drosophila J Zhu, Y Fu, A Richman, Z Han Bio-protocol 7 (12), 2017 | 11 | 2017 |
Autophagy inhibition rescues structural and functional defects caused by the loss of mitochondrial chaperone Hsc70-5 in Drosophila J Zhu, SB Hannan, NM Dräger, N Vereshchagina, AC Krahl, Y Fu, ... Autophagy 17 (10), 3160-3174, 2021 | 10 | 2021 |
Pharmacological or genetic inhibition of hypoxia signaling attenuates oncogenic RAS-induced cancer phenotypes J Zhu, X Huang, Y Fu, Y Wang, P Zheng, Y Liu, Z Han Disease models & mechanisms 15 (2), dmm048953, 2022 | 6 | 2022 |