| Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Y Ionov, MA Peinado, S Malkhosyan, D Shibata, M Perucho Nature 363 (6429), 558-561, 1993 | 3488 | 1993 |
| Insights into social insects from the genome of the honeybee Apis mellifera GM Weinstock, GE Robinson, RA Gibbs, KC Worley, JD Evans, ... Nature 443 (7114), 931-949, 2006 | 2072* | 2006 |
| Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus BM Javierre, AF Fernandez, J Richter, F Al-Shahrour, JI Martin-Subero, ... Genome research 20 (2), 170-179, 2010 | 746 | 2010 |
| Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer M Esteller, A Sparks, M Toyota, M Sanchez-Cespedes, G Capella, ... Cancer research 60 (16), 4366-4371, 2000 | 721 | 2000 |
| Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis M Esteller, M Toyota, M Sanchez-Cespedes, G Capella, MA Peinado, ... Cancer research 60 (9), 2368-2371, 2000 | 688 | 2000 |
| Hypermethylation-associated inactivation of p14ARF is independent of p16INK4a methylation and p53 mutational status M Esteller, S Tortola, M Toyota, G Capella, MA Peinado, SB Baylin, ... Cancer research 60 (1), 129-133, 2000 | 647 | 2000 |
| Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation D Shibata, MA Peinado, S Malkhosyan, M Perucho Nature genetics 6 (3), 273-281, 1994 | 633 | 1994 |
| DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis M Esteller, MF Fraga, M Guo, J Garcia-Foncillas, I Hedenfalk, AK Godwin, ... Human molecular genetics 10 (26), 3001-3007, 2001 | 591 | 2001 |
| regioneR: an R/Bioconductor package for the association analysis of genomic regions based on permutation tests B Gel, A Díez-Villanueva, E Serra, M Buschbeck, MA Peinado, ... Bioinformatics 32 (2), 289-291, 2016 | 478 | 2016 |
| Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band J Frigola, J Song, C Stirzaker, RA Hinshelwood, MA Peinado, SJ Clark Nature genetics 38 (5), 540-549, 2006 | 460 | 2006 |
| Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers J Rodriguez, J Frigola, E Vendrell, RA Risques, MF Fraga, C Morales, ... Cancer research 66 (17), 8462-9468, 2006 | 437 | 2006 |
| Promoter hypermethylation of the DNA repair gene O6-methylguanine-DNA methyltransferase is associated with the presence of G: C to A: T transition mutations in p53 in human … M Esteller, RA Risques, M Toyota, G Capella, V Moreno, MA Peinado, ... Cancer research 61 (12), 4689-4692, 2001 | 424 | 2001 |
| Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction MA Peinado, S Malkhosyan, A Velazquez, M Perucho Proceedings of the National Academy of Sciences 89 (21), 10065-10069, 1992 | 401 | 1992 |
| Functional CpG methylation system in a social insect Y Wang, M Jorda, PL Jones, R Maleszka, X Ling, HM Robertson, ... Science 314 (5799), 645-647, 2006 | 390 | 2006 |
| p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas L Hernandez, T Fest, M Cazorla, J Teruya-Feldstein, F Bosch, ... Blood 87 (8), 3351-3359, 1996 | 348 | 1996 |
| K-ras and p16 aberrations confer poor prognosis in human colorectal cancer M Esteller, S Gonzalez, RA Risques, E Marcuello, R Mangues, JR Germa, ... Journal of clinical oncology 19 (2), 299-304, 2001 | 339 | 2001 |
| Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors MF Paz, S Avila, MF Fraga, M Pollan, G Capella, MA Peinado, ... Cancer research 62 (15), 4519-4524, 2002 | 315 | 2002 |
| Comparative analysis of mutations in the p53 and K‐ras genes in pancreatic cancer G Berrozpe, J Schaeffer, MA Peinado, FX Real, M Perucho International journal of cancer 58 (2), 185-191, 1994 | 302 | 1994 |
| Frequency and spectrum of mutations at codons 12 and 13 of the cK-ras gene in human tumors. G Capella, S Cronauer-Mitra, MA Pienado, M Perucho Environmental health perspectives 93, 125-131, 1991 | 295 | 1991 |
| Epigenetics of Host–Pathogen Interactions: The Road Ahead and the Road Behind E Gómez-Díaz, M Jordà, MA Peinado, A Rivero PLoS Pathogens 8 (11), e1003007, 2012 | 282 | 2012 |
Manel EstellerDirector, Josep Carreras Leukaemia Research Institute. University of Barcelona and ICREA在 carrerasresearch.org 的电子邮件经过验证
