Liver ‘organ on a chip’ CH Beckwitt, AM Clark, S Wheeler, DL Taylor, DB Stolz, L Griffith, A Wells Experimental cell research 363 (1), 15-25, 2018 | 229 | 2018 |
Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment K Ito, K Stannard, E Gabutero, AM Clark, SY Neo, S Onturk, H Blanchard, ... Cancer and Metastasis Reviews 31, 763-778, 2012 | 155 | 2012 |
Liver metastases: Microenvironments and ex-vivo models AM Clark, B Ma, DL Taylor, L Griffith, A Wells Experimental Biology and Medicine 241 (15), 1639-1652, 2016 | 110 | 2016 |
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system SE Wheeler, AM Clark, DP Taylor, CL Young, VC Pillai, DB Stolz, ... British journal of cancer 111 (12), 2342-2350, 2014 | 87 | 2014 |
A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties AM Clark, SE Wheeler, CL Young, L Stockdale, J Shepard Neiman, ... Lab on a Chip, 2017 | 74 | 2017 |
Statins attenuate outgrowth of breast cancer metastases CH Beckwitt, AM Clark, B Ma, D Whaley, ZN Oltvai, A Wells British journal of cancer 119 (9), 1094-1105, 2018 | 73 | 2018 |
Inflammatory cytokine IL-8/CXCL8 promotes tumour escape from hepatocyte-induced dormancy AS Khazali, AM Clark, A Wells British journal of cancer 118 (4), 566-576, 2018 | 73 | 2018 |
Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells M Yang, B Ma, H Shao, AM Clark, A Wells BMC cancer 16, 1-13, 2016 | 72 | 2016 |
Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells N Dioufa, AM Clark, B Ma, CH Beckwitt, A Wells Molecular cancer 16, 1-14, 2017 | 68 | 2017 |
A microphysiological system model of therapy for liver micrometastases AM Clark, SE Wheeler, DP Taylor, VC Pillai, CL Young, R Prantil-Baun, ... Experimental biology and medicine 239 (9), 1170-1179, 2014 | 62 | 2014 |
A model of dormant-emergent metastatic breast cancer progression enabling exploration of biomarker signatures AM Clark, MP Kumar, SE Wheeler, CL Young, R Venkataramanan, ... Molecular & Cellular Proteomics 17 (4), 619-630, 2018 | 48 | 2018 |
Hepatic nonparenchymal cells drive metastatic breast cancer outgrowth and partial epithelial to mesenchymal transition DP Taylor, A Clark, S Wheeler, A Wells Breast cancer research and treatment 144 (3), 551-560, 2014 | 40 | 2014 |
Liver protects metastatic prostate cancer from induced death by activating E‐cadherin signaling B Ma, SE Wheeler, AM Clark, DL Whaley, M Yang, A Wells Hepatology 64 (5), 1725-1742, 2016 | 36 | 2016 |
The pan-therapeutic resistance of disseminated tumor cells: Role of phenotypic plasticity and the metastatic microenvironment B Ma, A Wells, AM Clark Seminars in cancer biology 60, 138-147, 2020 | 34 | 2020 |
All-human microphysical model of metastasis therapy SE Wheeler, JT Borenstein, AM Clark, MR Ebrahimkhani, IJ Fox, L Griffith, ... Stem cell research & therapy 4, 1-5, 2013 | 29 | 2013 |
A pathway to personalizing therapy for metastases using liver-on-a-chip platforms AS Khazali, AM Clark, A Wells Stem Cell Reviews and Reports 13, 364-380, 2017 | 26 | 2017 |
Quorum sensing negatively regulates multinucleate cell formation during intracellular growth of Burkholderia pseudomallei in macrophage-like cells RE Horton, GD Grant, B Matthews, M Batzloff, SJ Owen, S Kyan, CP Flegg, ... PloS one 8 (5), e63394, 2013 | 26 | 2013 |
Immunomodulatory activity of Melaleuca alternifolia concentrate (MAC): Inhibition of LPS-induced NF-κB activation and cytokine production in myeloid cell lines P Low, AM Clark, TC Chou, TC Chang, M Reynolds, SJ Ralph International Immunopharmacology 26 (1), 257-264, 2015 | 25 | 2015 |
Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells M Furukawa, S Wheeler, AM Clark, A Wells PloS one 10 (1), e0118060, 2015 | 25 | 2015 |
Atorvastatin facilitates chemotherapy effects in metastatic triple-negative breast cancer JLG Marti, CH Beckwitt, AM Clark, A Wells British Journal of Cancer 125 (9), 1285-1298, 2021 | 22 | 2021 |