Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2 S Banerjee, C Ji, JE Mayfield, A Goel, J Xiao, JE Dixon, X Guo Proceedings of the National Academy of Sciences 115 (32), 8155-8160, 2018 | 142 | 2018 |
Viewing serine/threonine protein phosphatases through the eyes of drug designers M Zhang, SD Yogesha, JE Mayfield, GN Gill, Y Zhang The FEBS journal 280 (19), 4739-4760, 2013 | 81 | 2013 |
Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain B Portz, F Lu, EB Gibbs, JE Mayfield, MR Mehaffey, YJ Zhang, JS Brodbelt, ... Nature communications 8 (1), 1-12, 2017 | 77 | 2017 |
Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression S Banerjee, T Wei, J Wang, JJ Lee, HL Gutierrez, O Chapman, SE Wiley, ... Proceedings of the National Academy of Sciences 116 (49), 24881-24891, 2019 | 49 | 2019 |
Dephosphorylating eukaryotic RNA polymerase II JE Mayfield, NT Burkholder, YJ Zhang Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1864 (4), 372-387, 2016 | 46 | 2016 |
Neuronal expression of the ubiquitin E3 ligase APC/C-Cdh1 during development is required for long-term potentiation, behavioral flexibility, and extinction JE Pick, L Wang, JE Mayfield, E Klann Neurobiology of learning and memory 100, 25-31, 2013 | 40 | 2013 |
Chemical tools to decipher regulation of phosphatases by proline isomerization on eukaryotic RNA polymerase II JE Mayfield, S Fan, S Wei, M Zhang, B Li, AD Ellington, FA Etzkorn, ... ACS chemical biology 10 (10), 2405-2414, 2015 | 32 | 2015 |
The ABCs of the atypical Fam20 secretory pathway kinases CA Worby, JE Mayfield, AJ Pollak, JE Dixon, S Banerjee Journal of Biological Chemistry 296, 2021 | 31 | 2021 |
Mapping the Phosphorylation Pattern of Drosophila melanogaster RNA Polymerase II Carboxyl-Terminal Domain Using Ultraviolet Photodissociation Mass … JE Mayfield, MR Robinson, VC Cotham, S Irani, WL Matthews, A Ram, ... ACS chemical biology 12 (1), 153-162, 2017 | 31 | 2017 |
Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb JE Mayfield, S Irani, EE Escobar, Z Zhang, NT Burkholder, MR Robinson, ... Elife 8, e48725, 2019 | 30 | 2019 |
Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides FL Li, V Fu, G Liu, T Tang, AW Konradi, X Peng, E Kemper, BF Cravatt, ... Nature Chemical Biology 18 (10), 1076-1086, 2022 | 26 | 2022 |
A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure AJ Pollak, C Liu, A Gudlur, JE Mayfield, ND Dalton, Y Gu, J Chen, ... Elife 7, e41378, 2018 | 26 | 2018 |
Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST) NT Burkholder, JE Mayfield, X Yu, S Irani, DK Arce, F Jiang, WL Matthews, ... Journal of Biological Chemistry 293 (43), 16851-16861, 2018 | 26 | 2018 |
Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase S Irani, SD Yogesha, J Mayfield, M Zhang, Y Zhang, WL Matthews, G Nie, ... Science signaling 9 (417), ra24-ra24, 2016 | 21 | 2016 |
Cross-talk of phosphorylation and prolyl isomerization of the C-terminal domain of RNA polymerase II SD Yogesha, JE Mayfield, Y Zhang Molecules 19 (2), 1481-1511, 2014 | 13 | 2014 |
Kinetic and thermodynamic analysis defines roles for two metal ions in DNA polymerase specificity and catalysis S Gong, S Kirmizialtin, A Chang, JE Mayfield, YJ Zhang, KA Johnson Journal of Biological Chemistry 296, 2021 | 12 | 2021 |
Structural Motifs for CTD Kinase Specificity on RNA Polymerase II during Eukaryotic Transcription MKV Ramani, EE Escobar, S Irani, JE Mayfield, RY Moreno, ... ACS chemical biology, 2020 | 10 | 2020 |
Ethanol and a rapid-acting antidepressant produce overlapping changes in exon expression in the synaptic transcriptome SA Wolfe, SP Farris, JE Mayfield, CF Heaney, EK Erickson, RA Harris, ... Neuropharmacology 146, 289-299, 2019 | 9 | 2019 |
Germline saturation mutagenesis induces skeletal phenotypes in mice JJ Rios, K Denton, J Russell, J Kozlitina, CR Ferreira, AF Lewanda, ... Journal of Bone and Mineral Research, 2021 | 7 | 2021 |
Ca2+-dependent liquid-liquid phase separation underlies intracellular Ca2+ stores. JE Mayfield, AJ Pollak, CA Worby, JC Xu, V Tandon, AC Newton, ... bioRxiv, 2021 | 5 | 2021 |