Genomewide association study of severe Covid-19 with respiratory failure Severe Covid-19 GWAS Group New England Journal of Medicine 383 (16), 1522-1534, 2020 | 1960 | 2020 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 764 | 2021 |
Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome MC Rühlemann, BM Hermes, C Bang, S Doms, L Moitinho-Silva, ... Nature Genetics 53 (2), 147-155, 2021 | 117 | 2021 |
The ABO blood group locus and a chromosome 3 gene cluster associate with SARS-CoV-2 respiratory failure in an Italian-Spanish genome-wide association … D Ellinghaus, F Degenhardt, L Bujanda, M Buti, A Albillos, P Invernizzi, ... MedRxiv, 2020.05. 31.20114991, 2020 | 110 | 2020 |
Development of a high-resolution NGS-based HLA-typing and analysis pipeline M Wittig, JA Anmarkrud, JC Kässens, S Koch, M Forster, E Ellinghaus, ... Nucleic Acids Research 43 (11), e70-e70, 2015 | 89 | 2015 |
Detailed stratified GWAS analysis for severe COVID-19 in four European populations F Degenhardt, D Ellinghaus, S Juzenas, J Lerga-Jaso, M Wendorff, ... Human molecular genetics 31 (23), 3945-3966, 2022 | 74* | 2022 |
Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression S Mucha, H Baurecht, N Novak, E Rodríguez, S Bej, G Mayr, H Emmert, ... Journal of Allergy and Clinical Immunology 145 (4), 1208-1218, 2020 | 44 | 2020 |
Severe Covid-19 GWAS Group D Ellinghaus, F Degenhardt, L Bujanda, M Buti, A Albillos, P Invernizzi, ... Genomewide association study of severe Covid-19 with respiratory failure. N …, 2020 | 38 | 2020 |
Parallelizing epistasis detection in GWAS on FPGA and GPU-accelerated computing systems J González-Domínguez, L Wienbrandt, JC Kässens, D Ellinghaus, ... IEEE/ACM transactions on computational biology and bioinformatics 12 (5 …, 2015 | 35 | 2015 |
FPGA-based acceleration of detecting statistical epistasis in GWAS L Wienbrandt, JC Kässens, J González-Domínguez, B Schmidt, ... Procedia Computer Science 29, 220-230, 2014 | 35 | 2014 |
High-speed exhaustive 3-locus interaction epistasis analysis on FPGAs JC Kässens, L Wienbrandt, J González-Domínguez, B Schmidt, ... Journal of Computational Science 9, 131-136, 2015 | 34 | 2015 |
A second update on mapping the human genetic architecture of COVID-19 M Kanai, SJ Andrews, M Cordioli, C Stevens, BM Neale, M Daly, A Ganna, ... Nature 621 (7977), E7-E26, 2023 | 31 | 2023 |
1000× faster than PLINK: Combined FPGA and GPU accelerators for logistic regression-based detection of epistasis L Wienbrandt, JC Kässens, M Hübenthal, D Ellinghaus Journal of Computational Science 30, 183-193, 2019 | 30 | 2019 |
Genome-wide study of a Neolithic Wartberg grave community reveals distinct HLA variation and hunter-gatherer ancestry A Immel, F Pierini, C Rinne, J Meadows, R Barquera, A Szolek, J Susat, ... Communications biology 4 (1), 113, 2021 | 26 | 2021 |
UPC++ for bioinformatics: A case study using genome-wide association studies JC Kässens, J González-Domínguez, L Wienbrandt, B Schmidt 2014 IEEE International Conference on Cluster Computing (CLUSTER), 248-256, 2014 | 24 | 2014 |
Hybrid CPU/GPU acceleration of detection of 2-SNP epistatic interactions in GWAS J González-Domínguez, B Schmidt, JC Kässens, L Wienbrandt Euro-Par 2014 Parallel Processing: 20th International Conference, Porto …, 2014 | 21 | 2014 |
UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment L Bastian, AM Hartmann, T Beder, S Hänzelmann, J Kässens, ... Leukemia 36 (6), 1676-1680, 2022 | 19 | 2022 |
Large-scale genome-wide association studies on a GPU cluster using a CUDA-accelerated PGAS programming model J González-Domínguez, JC Kässens, L Wienbrandt, B Schmidt The International Journal of High Performance Computing Applications 29 (4 …, 2015 | 16 | 2015 |
BIGwas: Single-command quality control and association testing for multi-cohort and biobank-scale GWAS/PheWAS data JC Kässens, L Wienbrandt, D Ellinghaus GigaScience 10 (6), giab047, 2021 | 14 | 2021 |
The gene expression classifier ALLCatchR identifies B-cell precursor ALL subtypes and underlying developmental trajectories across age T Beder, BT Hansen, AM Hartmann, J Zimmermann, E Amelunxen, ... Hemasphere 7 (9), e939, 2023 | 11 | 2023 |