In D-loop: 40 years of mitochondrial 7S DNA TJ Nicholls, M Minczuk Exp Ger 56, 175-181, 2014 | 332 | 2014 |
Mitochondrial genome engineering: the revolution may not be CRISPR-Ized PA Gammage, CT Moraes, M Minczuk Trends in Genetics 34 (2), 101-110, 2018 | 309 | 2018 |
Mitochondrially targeted ZFN s for selective degradation of pathogenic mitochondrial genomes bearing large‐scale deletions or point mutations PA Gammage, J Rorbach, AI Vincent, EJ Rebar, M Minczuk EMBO Molecular Medicine 6 (4), 458-466, 2014 | 305 | 2014 |
Mitochondrial transcription and translation: overview AR D’Souza, M Minczuk Essays in biochemistry 62 (3), 309-320, 2018 | 287 | 2018 |
Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo PA Gammage, C Viscomi, ML Simard, ASH Costa, E Gaude, CA Powell, ... Nature Medicine 24 (11), 1691-1695, 2018 | 275 | 2018 |
Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease C Kornblum, TJ Nicholls, TB Haack, S Schöler, V Peeva, K Danhauser, ... Nature Genetics 45 (2), 214, 2013 | 259 | 2013 |
Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA M Minczuk, MA Papworth, JC Miller, MP Murphy, A Klug Nucleic acids research 36 (12), 3926-3938, 2008 | 241 | 2008 |
NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction E Gaude, C Schmidt, PA Gammage, A Dugourd, T Blacker, SP Chew, ... Molecular Cell 69 (4), 581-593. e7, 2018 | 222 | 2018 |
Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3 L Van Haute, S Dietmann, L Kremer, S Hussain, SF Pearce, CA Powell, ... Nature communications 7 (1), 12039, 2016 | 211 | 2016 |
TEFM (c17orf42) is necessary for transcription of human mtDNA M Minczuk, J He, AM Duch, TJ Ettema, A Chlebowski, K Dzionek, ... Nucleic acids research 39 (10), 4284-4299, 2011 | 211 | 2011 |
Mitochondrial DNA replication in mammalian cells: overview of the pathway C Garone, M Minczuk, M Falkenberg Essays in biochemistry 62 (3), 287-296, 2018 | 196* | 2018 |
Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase M Minczuk, MA Papworth, P Kolasinska, MP Murphy, A Klug Proceedings of the National Academy of Sciences 103 (52), 19689-19694, 2006 | 195 | 2006 |
Linear mitochondrial DNA is rapidly degraded by components of the replication machinery V Peeva, D Blei, G Trombly, S Corsi, MJ Szukszto, P Rebelo-Guiomar, ... Nature communications 9 (1), 1727, 2018 | 189 | 2018 |
Regulation of mammalian mitochondrial gene expression: recent advances SF Pearce, P Rebelo-Guiomar, AR D’Souza, CA Powell, L Van Haute, ... Trends in biochemical sciences 42 (8), 625-639, 2017 | 188 | 2017 |
Designer zinc-finger proteins and their applications M Papworth, P Kolasinska, M Minczuk Gene 366 (1), 27-38, 2006 | 188 | 2006 |
The Yeast Mitochondrial Degradosome A Dziembowski, J Piwowarski, R Hoser, M Minczuk, A Dmochowska, ... Journal of Biological Chemistry 278 (3), 1603-1611, 2003 | 176 | 2003 |
Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes F Li, M Papworth, M Minczuk, C Rohde, Y Zhang, S Ragozin, A Jeltsch Nucleic acids research 35 (1), 100-112, 2007 | 169 | 2007 |
Emerging therapies for mitochondrial diseases C Garone, M Minczuk, Eds, M Hirano, V Emmanuele, CM Quinzii Essays in biochemistry 62 (3), 467-481, 2018 | 160 | 2018 |
ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy TB Haack, R Kopajtich, P Freisinger, T Wieland, J Rorbach, TJ Nicholls, ... The American Journal of Human Genetics 93 (2), 211-223, 2013 | 159 | 2013 |
Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors M Papworth, M Moore, M Isalan, M Minczuk, Y Choo, A Klug Proceedings of the National Academy of Sciences 100 (4), 1621-1626, 2003 | 158 | 2003 |