Transcription factors mediate long-range enhancer–promoter interactions IK Nolis, DJ McKay, E Mantouvalou, S Lomvardas, M Merika, D Thanos Proceedings of the National Academy of Sciences 106 (48), 20222-20227, 2009 | 227 | 2009 |
Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo KN Schulz, ER Bondra, A Moshe, JE Villalta, JD Lieb, T Kaplan, ... Genome research 25 (11), 1715-1726, 2015 | 177 | 2015 |
Direct integration of Hox and segmentation gene inputs during Drosophila development B Gebelein, DJ McKay, RS Mann Nature 431 (7009), 653-659, 2004 | 166 | 2004 |
Interrogating the function of metazoan histones using engineered gene clusters DJ McKay, S Klusza, TJR Penke, MP Meers, KP Curry, SL McDaniel, ... Developmental cell 32 (3), 373-386, 2015 | 151 | 2015 |
A common set of DNA regulatory elements shapes Drosophila appendages DJ McKay, JD Lieb Developmental cell 27 (3), 306-318, 2013 | 138 | 2013 |
Allele-specific mechanisms of activation of MEK1 mutants determine their properties Y Gao, MT Chang, D McKay, N Na, B Zhou, R Yaeger, NM Torres, ... Cancer discovery 8 (5), 648-661, 2018 | 121 | 2018 |
Molecular integration of wingless, decapentaplegic, and autoregulatory inputs into Distalless during Drosophila leg development C Estella, DJ McKay, RS Mann Developmental cell 14 (1), 86-96, 2008 | 102 | 2008 |
Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis DC Tatomer, E Terzo, KP Curry, H Salzler, I Sabath, G Zapotoczny, ... Journal of Cell Biology 213 (5), 557-570, 2016 | 95 | 2016 |
Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax B Noro, J Culi, DJ McKay, W Zhang, RS Mann Genes & development 20 (12), 1636-1650, 2006 | 94 | 2006 |
Hormone-dependent control of developmental timing through regulation of chromatin accessibility CM Uyehara, SL Nystrom, MJ Niederhuber, M Leatham-Jensen, Y Ma, ... Genes & development 31 (9), 862-875, 2017 | 93 | 2017 |
Direct and widespread role for the nuclear receptor EcR in mediating the response to ecdysone in Drosophila CM Uyehara, DJ McKay Proceedings of the National Academy of Sciences 116 (20), 9893-9902, 2019 | 81 | 2019 |
Direct interrogation of the role of H3K9 in metazoan heterochromatin function TJR Penke, DJ McKay, BD Strahl, AG Matera, RJ Duronio Genes & development 30 (16), 1866-1880, 2016 | 69 | 2016 |
Allosteric mutant IDH1 inhibitors reveal mechanisms for IDH1 mutant and isoform selectivity X Xie, D Baird, K Bowen, V Capka, J Chen, G Chenail, YS Cho, J Dooley, ... Structure 25 (3), 506-513, 2017 | 63 | 2017 |
Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo KN Schaefer, TT Bonello, S Zhang, CE Williams, DM Roberts, DJ McKay, ... PLoS genetics 14 (4), e1007339, 2018 | 62 | 2018 |
The origins of the Drosophila leg revealed by the cis-regulatory architecture of the Distalless gene DJ McKay, C Estella, RS Mann Oxford University Press for The Company of Biologists Limited 136 (1), 61-71, 2009 | 56 | 2009 |
LXH254, a potent and selective ARAF-sparing inhibitor of BRAF and CRAF for the treatment of MAPK-driven tumors KA Monaco, S Delach, J Yuan, Y Mishina, P Fordjour, E Labrot, D McKay, ... Clinical cancer research 27 (7), 2061-2073, 2021 | 53 | 2021 |
Developmental regulation of chromatin conformation by Hox proteins in Drosophila M Agelopoulos, DJ McKay, RS Mann Cell reports 1 (4), 350-359, 2012 | 52 | 2012 |
Memes: A motif analysis environment in R using tools from the MEME Suite SL Nystrom, DJ McKay PLoS Computational Biology 17 (9), e1008991, 2021 | 49 | 2021 |
Changes in chromatin accessibility ensure robust cell cycle exit in terminally differentiated cells Y Ma, DJ McKay, L Buttitta PLoS Biology 17 (9), e3000378, 2019 | 48 | 2019 |
Enhancer identification and activity evaluation in the red flour beetle, Tribolium castaneum YT Lai, KD Deem, F Borràs-Castells, N Sambrani, H Rudolf, ... Development 145 (7), dev160663, 2018 | 47 | 2018 |