| Spiroindolones, a potent compound class for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... science 329 (5996), 1175-1180, 2010 | 1253 | 2010 |
| In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen D Plouffe, A Brinker, C McNamara, K Henson, N Kato, K Kuhen, A Nagle, ... Proceedings of the National Academy of Sciences 105 (26), 9059-9064, 2008 | 531 | 2008 |
| Targeting Plasmodium PI(4)K to eliminate malaria CW McNamara, MCS Lee, CS Lim, SH Lim, J Roland, A Nagle, O Simon, ... Nature 504 (7479), 248-253, 2013 | 446 | 2013 |
| Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ... Science 334 (6061), 1372-1377, 2011 | 370 | 2011 |
| Na+ regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials NJ Spillman, RJW Allen, CW McNamara, BKS Yeung, EA Winzeler, ... Cell host & microbe 13 (2), 227-237, 2013 | 252 | 2013 |
| Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility N Kato, T Sakata, G Breton, KG Le Roch, A Nagle, C Andersen, ... Nature chemical biology 4 (6), 347-356, 2008 | 249 | 2008 |
| Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families SER Bopp, MJ Manary, AT Bright, GL Johnston, NV Dharia, FL Luna, ... PLoS genetics 9 (2), e1003293, 2013 | 246 | 2013 |
| Selective and specific inhibition of the Plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin D Hoepfner, CW McNamara, CS Lim, C Studer, R Riedl, T Aust, ... Cell host & microbe 11 (6), 654-663, 2012 | 244 | 2012 |
| M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition X Lauth, M von Köckritz-Blickwede, CW McNamara, S Myskowski, ... Journal of innate immunity 1 (3), 202-214, 2009 | 218 | 2009 |
| Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence C McNamara, AS Zinkernagel, P Macheboeuf, MW Cunningham, V Nizet, ... Science 319 (5868), 1405-1408, 2008 | 193 | 2008 |
| The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis J Janes, ME Young, E Chen, NH Rogers, S Burgstaller-Muehlbacher, ... Proceedings of the National Academy of Sciences 115 (42), 10750-10755, 2018 | 177 | 2018 |
| A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum A Roth, SP Maher, AJ Conway, R Ubalee, V Chaumeau, C Andolina, ... Nature communications 9 (1), 1837, 2018 | 160 | 2018 |
| A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis MS Love, FC Beasley, RS Jumani, TM Wright, AK Chatterjee, CD Huston, ... PLoS neglected tropical diseases 11 (2), e0005373, 2017 | 119 | 2017 |
| Open-source discovery of chemical leads for next-generation chemoprotective antimalarials Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ... Science 362 (6419), eaat9446, 2018 | 112 | 2018 |
| Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ... Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019 | 111 | 2019 |
| Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design MB Harbut, BA Patel, BKS Yeung, CW McNamara, AT Bright, J Ballard, ... Proceedings of the National Academy of Sciences 109 (52), 21486-21491, 2012 | 110 | 2012 |
| A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor T Nam, CW McNamara, S Bopp, NV Dharia, S Meister, GMC Bonamy, ... ACS chemical biology 6 (11), 1214-1222, 2011 | 107 | 2011 |
| Drug repurposing screens identify chemical entities for the development of COVID-19 interventions MA Bakowski, N Beutler, KC Wolff, MG Kirkpatrick, E Chen, TTH Nguyen, ... Nature communications 12 (1), 3309, 2021 | 100 | 2021 |
| Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials EL Flannery, CW McNamara, SW Kim, TS Kato, F Li, CH Teng, ... ACS chemical biology 10 (2), 413-420, 2015 | 99 | 2015 |
| High-throughput luciferase-based assay for the discovery of therapeutics that prevent malaria J Swann, V Corey, CA Scherer, N Kato, E Comer, M Maetani, ... ACS infectious diseases 2 (4), 281-293, 2016 | 98 | 2016 |
