Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 434 | 2017 |
Functional convergence of oxylipin and abscisic acid pathways controls stomatal closure in response to drought T Savchenko, VA Kolla, CQ Wang, Z Nasafi, DR Hicks, B Phadungchob, ... Plant physiology 164 (3), 1151-1160, 2014 | 284 | 2014 |
Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 270 | 2022 |
Human CTP synthase filament structure reveals the active enzyme conformation EM Lynch, DR Hicks, M Shepherd, JA Endrizzi, A Maker, JM Hansen, ... Nature structural & molecular biology 24 (6), 507-514, 2017 | 164 | 2017 |
A key general stress response motif is regulated non‐uniformly by CAMTA transcription factors G Benn, CQ Wang, DR Hicks, J Stein, C Guthrie, K Dehesh The Plant Journal 80 (1), 82-92, 2014 | 86 | 2014 |
The plastidial retrograde signal methyl erythritol cyclopyrophosphate is a regulator of salicylic acid and jasmonic acid crosstalk M Lemos, Y Xiao, M Bjornson, J Wang, D Hicks, A Souza, CQ Wang, ... Journal of Experimental Botany 67 (5), 1557-1566, 2016 | 59 | 2016 |
Supplementation with abscisic acid reduces malaria disease severity and parasite transmission EKK Glennon, LG Adams, DR Hicks, K Dehesh, S Luckhart The American journal of tropical medicine and hygiene 94 (6), 1266, 2016 | 32 | 2016 |
De novo design of modular peptide-binding proteins by superhelical matching K Wu, H Bai, YT Chang, R Redler, KE McNally, W Sheffler, TJ Brunette, ... Nature 616 (7957), 581-589, 2023 | 27 | 2023 |
De novo design of protein homodimers containing tunable symmetric protein pockets DR Hicks, MA Kennedy, KA Thompson, M DeWitt, B Coventry, A Kang, ... Proceedings of the National Academy of Sciences 119 (30), e2113400119, 2022 | 16 | 2022 |
ORA47 is a transcriptional regulator of a general stress response hub L Zeng, H Chen, Y Wang, D Hicks, H Ke, J Pruneda‐Paz, K Dehesh The Plant Journal 110 (2), 562-571, 2022 | 9 | 2022 |
Hallucination of closed repeat proteins containing central pockets L An, DR Hicks, D Zorine, J Dauparas, BIM Wicky, LF Milles, A Courbet, ... Nature Structural & Molecular Biology 30 (11), 1755-1760, 2023 | 6 | 2023 |
Binding and sensing diverse small molecules using shape-complementary pseudocycles L An, M Said, L Tran, S Majumder, I Goreshnik, GR Lee, D Juergens, ... Science 385 (6706), 276-282, 2024 | 5 | 2024 |
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies NI Edman, A Phal, RL Redler, T Schlichthaerle, SR Srivatsan, DD Ehnes, ... Cell 187 (14), 3726-3740. e43, 2024 | 4 | 2024 |
Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins SR Gerben, AJ Borst, DR Hicks, I Moczygemba, D Feldman, B Coventry, ... Biochemistry 62 (2), 358-368, 2023 | 4 | 2023 |
De novo design of buttressed loops for sculpting protein functions H Jiang, KM Jude, K Wu, J Fallas, G Ueda, TJ Brunette, DR Hicks, H Pyles, ... Nature Chemical Biology, 1-7, 2024 | 3 | 2024 |
Design of High Affinity Binders to Convex Protein Target Sites W Yang, DR Hicks, A Ghosh, TA Schwartze, B Conventry, I Goreshnik, ... bioRxiv, 2024 | 1 | 2024 |
In vivo selection of synthetic nucleocapsids for tissue targeting A Olshefsky, H Benasutti, M Sylvestre, GL Butterfield, GJ Rocklin, ... Proceedings of the National Academy of Sciences 120 (46), e2306129120, 2023 | 1 | 2023 |
De novo design of proteins housing excitonically coupled chlorophyll special pairs NM Ennist, S Wang, MA Kennedy, M Curti, GA Sutherland, C Vasilev, ... Nature Chemical Biology, 1-10, 2024 | | 2024 |
Sequence-specific targeting of intrinsically disordered protein regions K Wu, H Jiang, DR Hicks, C Liu, E Muratspahic, TA Ramelot, Y Liu, ... bioRxiv, 2024.07. 15.603480, 2024 | | 2024 |
Scaffolding protein functional sites using deep learning D Baker, J Wang, R Ragotte, L Milles, JL Watson, D Juergens, S Lisanza, ... US Patent App. 18/339,519, 2023 | | 2023 |