Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA PH Reddy, M Williams, V Charles, L Garrett, L Pike-Buchanan, ... Nature genetics 20 (2), 198-202, 1998 | 526 | 1998 |
Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways CA Altar, P Laeng, LW Jurata, JA Brockman, A Lemire, J Bullard, ... Journal of Neuroscience 24 (11), 2667-2677, 2004 | 405 | 2004 |
Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts CA Altar, LW Jurata, V Charles, A Lemire, P Liu, Y Bukhman, TA Young, ... Biological psychiatry 58 (2), 85-96, 2005 | 341 | 2005 |
Development of local circuits in human visual cortex A Burkhalter, KL Bernardo, V Charles Journal of Neuroscience 13 (5), 1916-1931, 1993 | 334 | 1993 |
Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production P Guidetti, V Charles, EY Chen, PH Reddy, JH Kordower, WO Whetsell Jr, ... Experimental neurology 169 (2), 340-350, 2001 | 232 | 2001 |
PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains J Modregger, NA DiProspero, V Charles, DA Tagle, M Plomann Human molecular genetics 11 (21), 2547-2558, 2002 | 198 | 2002 |
Early changes in Huntington’s disease patient brains involve alterations in cytoskeletal and synaptic elements NA DiProspero, EY Chen, V Charles, M Plomann, JH Kordower, DA Tagle Journal of neurocytology 33, 517-533, 2004 | 185 | 2004 |
Grafts of EGF‐responsive neural stem cells derived from GFAP‐hNGF transgenic mice: Trophic and tropic effects in a rodent model of Huntington's disease JH Kordower, EY Chen, C Winkler, R Fricker, V Charles, A Messing, ... Journal of Comparative Neurology 387 (1), 96-113, 1997 | 148 | 1997 |
Intravenous administration of a transferrin receptor antibody-nerve growth factor conjugate prevents the degeneration of cholinergic striatal neurons in a model of Huntington … JH Kordower, V Charles, R Bayer, RT Bartus, S Putney, LR Walus, ... Proceedings of the National Academy of Sciences 91 (19), 9077-9080, 1994 | 131 | 1994 |
Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease P Hemachandra Reddy, V Charles, M Williams, G Miller, WO Whetsell Jr, ... Philosophical Transactions of the Royal Society of London. Series B …, 1999 | 100 | 1999 |
Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease VV Senatorov, V Charles, PH Reddy, DA Tagle, DM Chuang Molecular and Cellular Neuroscience 22 (3), 285-297, 2003 | 85 | 2003 |
Alpha-synuclein immunoreactivity of huntingtin polyglutamine aggregates in striatum and cortex of Huntington's disease patients and transgenic mouse models V Charles, E Mezey, PH Reddy, A Dehejia, TA Young, ... Neuroscience letters 289 (1), 29-32, 2000 | 82 | 2000 |
Organization of local axon collaterals of efferent projection neurons in rat visual cortex A Burkhalter, V Charles Journal of comparative neurology 302 (4), 920-934, 1990 | 75 | 1990 |
Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate V Charles, EJ Mufson, PM Friden, RT Bartus, JH Kordower Brain research 728 (2), 193-203, 1996 | 68 | 1996 |
Comparison of microarray-based mRNA profiling technologies for identification of psychiatric disease and drug signatures LW Jurata, YV Bukhman, V Charles, F Capriglione, J Bullard, AL Lemire, ... Journal of neuroscience methods 138 (1-2), 173-188, 2004 | 62 | 2004 |
Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors R Hanbury, V Charles, EY Chen, L Leventhal, JM Rosenstein, EJ Mufson, ... Journal of Comparative Neurology 444 (4), 291-305, 2002 | 43 | 2002 |
Altered expression of hippocampal dentate granule neuron genes in a mouse model of human 22q11 deletion syndrome LW Jurata, P Gallagher, AL Lemire, V Charles, JA Brockman, ... Schizophrenia research 88 (1-3), 251-259, 2006 | 25 | 2006 |
Assessment of long-term effects of transient anoxia on metabolic activity of rat hippocampal slices using triphenyltetrazolium chloride GB Watson, OT Lopez, VD Charles, TH Lanthorn Journal of neuroscience methods 53 (2), 203-208, 1994 | 20 | 1994 |
Gene signature of electroshock therapy and methods of use CA Altar, P Laeng, T Young, V Charles US Patent App. 10/664,705, 2004 | 15 | 2004 |
Dissociation of p75 receptors and nerve growth factor neurotrophic effects: lack of p75 immunoreactivity in striatum following physical trauma, excitotoxicity and NGF … RT Bartus, RL Dean, S Abelleira, V Charles, JH Kordower Restorative neurology and neuroscience 10 (1), 49-59, 1996 | 8 | 1996 |