Complex pectin metabolism by gut bacteria reveals novel catalytic functions D Ndeh, A Rogowski, A Cartmell, AS Luis, A Baslé, J Gray, I Venditto, ... Nature 544 (7648), 65-70, 2017 | 561 | 2017 |
Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism F Cuskin, EC Lowe, MJ Temple, Y Zhu, EA Cameron, NA Pudlo, NT Porter, ... Nature 517 (7533), 165-169, 2015 | 523 | 2015 |
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides AS Luis, J Briggs, X Zhang, B Farnell, D Ndeh, A Labourel, A Baslé, ... Nature microbiology 3 (2), 210-219, 2018 | 326 | 2018 |
A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation A Cartmell, J Muñoz-Muñoz, JA Briggs, DA Ndeh, EC Lowe, A Baslé, ... Nature microbiology 3 (11), 1314-1326, 2018 | 118 | 2018 |
How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans A Cartmell, EC Lowe, A Baslé, SJ Firbank, DA Ndeh, H Murray, ... Proceedings of the National Academy of Sciences 114 (27), 7037-7042, 2017 | 118 | 2017 |
A single sulfatase is required to access colonic mucin by a gut bacterium AS Luis, C Jin, GV Pereira, RWP Glowacki, SR Gugel, S Singh, DP Byrne, ... Nature 598 (7880), 332-337, 2021 | 115 | 2021 |
The structure and function of an arabinan-specific α-1, 2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases A Cartmell, LS McKee, MJ Pena, J Larsbrink, H Brumer, S Kaneko, ... Journal of Biological Chemistry 286 (17), 15483-15495, 2011 | 109 | 2011 |
Structural insights into a unique cellulase fold and mechanism of cellulose hydrolysis JLA Brás, A Cartmell, ALM Carvalho, G Verzé, EA Bayer, Y Vazana, ... Proceedings of the National Academy of Sciences 108 (13), 5237-5242, 2011 | 106 | 2011 |
The Cellvibrio japonicus mannanase CjMan26C displays a unique exo-mode of action that is conferred by subtle changes to the distal region of the active site A Cartmell, E Topakas, VMA Ducros, MDL Suits, GJ Davies, HJ Gilbert Journal of Biological Chemistry 283 (49), 34403-34413, 2008 | 94 | 2008 |
The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions C Montanier, VA Money, VMR Pires, JE Flint, BA Pinheiro, A Goyal, ... PLoS biology 7 (3), e1000071, 2009 | 80 | 2009 |
Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus D Ndeh, A Baslé, H Strahl, EA Yates, UL McClurgg, B Henrissat, ... Nature communications 11 (1), 646, 2020 | 78 | 2020 |
Recognition of xyloglucan by the crystalline cellulose-binding site of a family 3a carbohydrate-binding module MC Hernandez-Gomez, MG Rydahl, A Rogowski, C Morland, A Cartmell, ... FEBS letters 589 (18), 2297-2303, 2015 | 58 | 2015 |
Analysis of the structural and functional diversity of plant cell wall specific family 6 carbohydrate binding modules DW Abbott, E Ficko-Blean, AL van Bueren, A Rogowski, A Cartmell, ... Biochemistry 48 (43), 10395-10404, 2009 | 53 | 2009 |
Insights into SusCD-mediated glycan import by a prominent gut symbiont DA Gray, JBR White, AO Oluwole, P Rath, AJ Glenwright, A Mazur, ... Nature communications 12 (1), 44, 2021 | 51 | 2021 |
Unusual active site location and catalytic apparatus in a glycoside hydrolase family J Munoz-Munoz, A Cartmell, N Terrapon, B Henrissat, HJ Gilbert Proceedings of the National Academy of Sciences 114 (19), 4936-4941, 2017 | 51 | 2017 |
Evidence for a Boat Conformation at the Transition State of GH76 α‐1, 6‐Mannanases—Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism AJ Thompson, G Speciale, J Iglesias‐Fernández, Z Hakki, T Belz, ... Angewandte Chemie International Edition 54 (18), 5378-5382, 2015 | 51 | 2015 |
Dietary pectic glycans are degraded by coordinated enzyme pathways in human colonic Bacteroides. Nat Microbiol 3: 210–219 AS Luis, J Briggs, X Zhang, B Farnell, D Ndeh, A Labourel, A Baslé, ... | 36 | 2018 |
The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29 D Ndeh, JM Munoz, A Cartmell, D Bulmer, C Wills, B Henrissat, J Gray Journal of Biological Chemistry 293 (46), 17906-17916, 2018 | 35 | 2018 |
An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins J Munoz-Munoz, A Cartmell, N Terrapon, A Baslé, B Henrissat, HJ Gilbert Journal of Biological Chemistry 292 (32), 13271-13283, 2017 | 32 | 2017 |
Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota AS Luis, A Baslé, DP Byrne, GSA Wright, JA London, C Jin, NG Karlsson, ... Nature chemical biology 18 (8), 841-849, 2022 | 23 | 2022 |