| Glucose metabolism in the progression of prostate cancer F Cutruzzolà, G Giardina, M Marani, A Macone, A Paiardini, S Rinaldo, ... Frontiers in physiology 8, 97, 2017 | 145 | 2017 |
| SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation A Paone, M Marani, A Fiascarelli, S Rinaldo, G Giardina, R Contestabile, ... Cell death & disease 5 (11), e1525-e1525, 2014 | 122 | 2014 |
| NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR G Giardina, S Rinaldo, KA Johnson, A Di Matteo, M Brunori, F Cutruzzolà Journal of molecular biology 378 (5), 1002-1015, 2008 | 106 | 2008 |
| How pyridoxal 5′‐phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state G Giardina, P Brunotti, A Fiascarelli, A Cicalini, MGS Costa, AM Buckle, ... The FEBS journal 282 (7), 1225-1241, 2015 | 95 | 2015 |
| The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability D Antoniani, E Rossi, S Rinaldo, P Bocci, M Lolicato, A Paiardini, ... Applied microbiology and biotechnology 97, 7325-7336, 2013 | 83 | 2013 |
| Nitrite and nitrite reductases: from molecular mechanisms to significance in human health and disease N Castiglione, S Rinaldo, G Giardina, V Stelitano, F Cutruzzolà Antioxidants & redox signaling 17 (4), 684-716, 2012 | 81 | 2012 |
| C-di-GMP Hydrolysis by Pseudomonas aeruginosa HD-GYP Phosphodiesterases: Analysis of the Reaction Mechanism and Novel Roles for pGpG V Stelitano, G Giardina, A Paiardini, N Castiglione, F Cutruzzolà, ... PLoS One 8 (9), e74920, 2013 | 76 | 2013 |
| Fractalkine modulates microglia metabolism in brain ischemia C Lauro, G Chece, L Monaco, F Antonangeli, G Peruzzi, S Rinaldo, ... Frontiers in cellular neuroscience 13, 414, 2019 | 69 | 2019 |
| In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed F Daidone, R Florio, S Rinaldo, R Contestabile, ML di Salvo, F Cutruzzolà, ... European journal of medicinal chemistry 46 (5), 1616-1621, 2011 | 67 | 2011 |
| The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli N Castiglione, S Rinaldo, G Giardina, F Cutruzzola Microbiology 155 (9), 2838-2844, 2009 | 67 | 2009 |
| Beyond nitrogen metabolism: nitric oxide, cyclic-di-GMP and bacterial biofilms S Rinaldo, G Giardina, F Mantoni, A Paone, F Cutruzzolà FEMS microbiology letters 365 (6), fny029, 2018 | 65 | 2018 |
| Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain G Giardina, A Paiardini, S Fernicola, S Franceschini, S Rinaldo, ... PloS one 8 (11), e81324, 2013 | 60 | 2013 |
| A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells M Marani, A Paone, A Fiascarelli, A Macone, M Gargano, S Rinaldo, ... Oncotarget 7 (4), 4570, 2016 | 59 | 2016 |
| Nitrite reductases in denitrification S Rinaldo, F Cutruzzolà Biology of the nitrogen cycle, 37-55, 2007 | 59 | 2007 |
| Probing the activity of diguanylate cyclases and c-di-GMP phosphodiesterases in real-time by CD spectroscopy V Stelitano, A Brandt, S Fernicola, S Franceschini, G Giardina, A Pica, ... Nucleic acids research 41 (7), e79-e79, 2013 | 53 | 2013 |
| In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD S Fernicola, A Paiardini, G Giardina, G Rampioni, L Leoni, F Cutruzzolà, ... Journal of bacteriology 198 (1), 147-156, 2016 | 50 | 2016 |
| Fast dissociation of nitric oxide from ferrous Pseudomonas aeruginosa cd1 nitrite reductase: A novel outlook on the catalytic mechanism S Rinaldo, A Arcovito, M Brunori, F Cutruzzola Journal of Biological Chemistry 282 (20), 14761-14767, 2007 | 50 | 2007 |
| Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site S Rinaldo, A Paiardini, V Stelitano, P Brunotti, L Cervoni, S Fernicola, ... Journal of bacteriology 197 (8), 1525-1535, 2015 | 46 | 2015 |
| A dramatic conformational rearrangement is necessary for the activation of DNR from Pseudomonas aeruginosa. Crystal structure of wild‐type DNR G Giardina, S Rinaldo, N Castiglione, M Caruso, F Cutruzzola Proteins: Structure, Function, and Bioinformatics 77 (1), 174-180, 2009 | 44 | 2009 |
| Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase A Paiardini, A Fiascarelli, S Rinaldo, F Daidone, G Giardina, DR Koes, ... ChemMedChem 10 (3), 490-497, 2015 | 41 | 2015 |
