Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies G Wang, ML McCain, L Yang, A He, FS Pasqualini, A Agarwal, H Yuan, ... Nature medicine 20 (6), 616-623, 2014 | 899 | 2014 |
A tissue-engineered jellyfish with biomimetic propulsion JC Nawroth, H Lee, AW Feinberg, CM Ripplinger, ML McCain, ... Nature biotechnology 30 (8), 792-797, 2012 | 703 | 2012 |
Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip A Grosberg, PW Alford, ML McCain, KK Parker Lab on a Chip 11 (24), 4165-4173, 2011 | 631 | 2011 |
Microfluidic heart on a chip for higher throughput pharmacological studies A Agarwal, JA Goss, A Cho, ML McCain, KK Parker Lab on a Chip 13 (18), 3599-3608, 2013 | 560 | 2013 |
Mechanotransduction: the role of mechanical stress, myocyte shape, and cytoskeletal architecture on cardiac function ML McCain, KK Parker Pflügers Archiv-European Journal of Physiology 462, 89-104, 2011 | 275 | 2011 |
Micromolded gelatin hydrogels for extended culture of engineered cardiac tissues ML McCain, A Agarwal, HW Nesmith, AP Nesmith, KK Parker Biomaterials 35 (21), 5462-5471, 2014 | 239 | 2014 |
Cooperative coupling of cell-matrix and cell–cell adhesions in cardiac muscle ML McCain, H Lee, Y Aratyn-Schaus, AG Kléber, KK Parker Proceedings of the National Academy of Sciences 109 (25), 9881-9886, 2012 | 235 | 2012 |
Muscle on a chip: in vitro contractility assays for smooth and striated muscle A Grosberg, AP Nesmith, JA Goss, MD Brigham, ML McCain, KK Parker Journal of pharmacological and toxicological methods 65 (3), 126-135, 2012 | 205 | 2012 |
Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip ML McCain, SP Sheehy, A Grosberg, JA Goss, KK Parker Proceedings of the National Academy of Sciences 110 (24), 9770-9775, 2013 | 165 | 2013 |
Prolonged culture of aligned skeletal myotubes on micromolded gelatin hydrogels A Bettadapur, GC Suh, NA Geisse, ER Wang, C Hua, HA Huber, ... Scientific reports 6 (1), 28855, 2016 | 148 | 2016 |
Micropatterning alginate substrates for in vitro cardiovascular muscle on a chip A Agarwal, Y Farouz, AP Nesmith, LF Deravi, ML McCain, KK Parker Advanced functional materials 23 (30), 3738-3746, 2013 | 147 | 2013 |
Matrix elasticity regulates the optimal cardiac myocyte shape for contractility ML McCain, H Yuan, FS Pasqualini, PH Campbell, KK Parker American Journal of Physiology-Heart and Circulatory Physiology 306 (11 …, 2014 | 141 | 2014 |
Connexin 43 expression delineates two discrete pathways in the human atrioventricular junction WJ Hucker, ML Mccain, JI Laughner, PA Iaizzo, IR Efimov The Anatomical Record: Advances in Integrative Anatomy and Evolutionary …, 2008 | 114 | 2008 |
Human airway musculature on a chip: an in vitro model of allergic asthmatic bronchoconstriction and bronchodilation AP Nesmith, A Agarwal, ML McCain, KK Parker Lab on a chip 14 (20), 3925-3936, 2014 | 84 | 2014 |
Cell-to-cell coupling in engineered pairs of rat ventricular cardiomyocytes: relation between Cx43 immunofluorescence and intercellular electrical conductance ML McCain, T Desplantez, NA Geisse, B Rothen-Rutishauser, H Oberer, ... American journal of physiology-heart and circulatory physiology 302 (2 …, 2012 | 80 | 2012 |
Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current T Desplantez, ML McCain, P Beauchamp, G Rigoli, B Rothen-Rutishauser, ... Cardiovascular research 94 (1), 58-65, 2012 | 79 | 2012 |
Featured Article: TGF-β1 dominates extracellular matrix rigidity for inducing differentiation of human cardiac fibroblasts to myofibroblasts N Cho, SE Razipour, ML McCain Experimental Biology and Medicine 243 (7), 601-612, 2018 | 69 | 2018 |
Electrical coupling and propagation in engineered ventricular myocardium with heterogeneous expression of connexin43 P Beauchamp, T Desplantez, ML McCain, W Li, A Asimaki, G Rigoli, ... Circulation research 110 (11), 1445-1453, 2012 | 63 | 2012 |
Coupling primary and stem cell–derived cardiomyocytes in an in vitro model of cardiac cell therapy Y Aratyn-Schaus, FS Pasqualini, H Yuan, ML McCain, GJC Ye, ... Journal of Cell Biology 212 (4), 389-397, 2016 | 57 | 2016 |
Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment DM Lyra-Leite, AM Andres, AP Petersen, NR Ariyasinghe, N Cho, JA Lee, ... American Journal of Physiology-Heart and Circulatory Physiology 313 (4 …, 2017 | 55 | 2017 |