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Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans MR Scott, R Will, J Ironside, HOB Nguyen, P Tremblay, SJ DeArmond, ... Proceedings of the National Academy of Sciences 96 (26), 15137-15142, 1999 | 735 | 1999 |
Prion protein selectively binds copper (II) ions J Stöckel, J Safar, AC Wallace, FE Cohen, SB Prusiner Biochemistry 37 (20), 7185-7193, 1998 | 670 | 1998 |
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Diagnosis of human prion disease JG Safar, MD Geschwind, C Deering, S Didorenko, M Sattavat, ... Proceedings of the National Academy of Sciences 102 (9), 3501-3506, 2005 | 346 | 2005 |
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC BR Groveman, CD Orrù, AG Hughson, LD Raymond, G Zanusso, B Ghetti, ... Acta neuropathologica communications 6, 1-10, 2018 | 314 | 2018 |
Branched polyamines cure prion-infected neuroblastoma cells S Supattapone, H Wille, L Uyechi, J Safar, P Tremblay, FC Szoka, ... Journal of virology 75 (7), 3453-3461, 2001 | 289 | 2001 |
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice JG Safar, M Scott, J Monaghan, C Deering, S Didorenko, J Vergara, ... Nature biotechnology 20 (11), 1147-1150, 2002 | 281 | 2002 |
Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity J Safar, PP Roller, DC Gajdusek, CJ Gibbs Jr Protein Science 2 (12), 2206-2216, 1993 | 277 | 1993 |
Prion protein of 106 residues creates an artificial transmission barrier for prion replication in transgenic mice S Supattapone, P Bosque, T Muramoto, H Wille, C Aagaard, D Peretz, ... Cell 96 (6), 869-878, 1999 | 269 | 1999 |
Mimicking dominant negative inhibition of prion replication through structure-based drug design V Perrier, AC Wallace, K Kaneko, J Safar, SB Prusiner, FE Cohen Proceedings of the National Academy of Sciences 97 (11), 6073-6078, 2000 | 245 | 2000 |
Phosphorylated tau interactome in the human Alzheimer’s disease brain E Drummond, G Pires, C MacMurray, M Askenazi, S Nayak, M Bourdon, ... Brain 143 (9), 2803-2817, 2020 | 221 | 2020 |
Transmission of elk and deer prions to transgenic mice G Tamgüney, K Giles, E Bouzamondo-Bernstein, PJ Bosque, MW Miller, ... Journal of virology 80 (18), 9104-9114, 2006 | 219 | 2006 |
Diagnostic and prognostic value of human prion detection in cerebrospinal fluid A Foutz, BS Appleby, C Hamlin, X Liu, S Yang, Y Cohen, W Chen, ... Annals of neurology 81 (1), 79-92, 2017 | 214 | 2017 |
Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice MR Scott, J Safar, G Telling, O Nguyen, D Groth, M Torchia, R Koehler, ... Proceedings of the National Academy of Sciences 94 (26), 14279-14284, 1997 | 212 | 1997 |
Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer’s disease E Drummond, S Nayak, A Faustin, G Pires, RA Hickman, M Askenazi, ... Acta neuropathologica 133, 933-954, 2017 | 205 | 2017 |
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Dominant-negative inhibition of prion replication in transgenic mice V Perrier, K Kaneko, J Safar, J Vergara, P Tremblay, SJ DeArmond, ... Proceedings of the National Academy of Sciences 99 (20), 13079-13084, 2002 | 194 | 2002 |