A prooxidant mechanism for the anticancer and chemopreventive properties of plant polyphenols H Yar Khan, H Zubair, M Fahad Ullah, A Ahmad, S Mumtaz Hadi Current Drug Targets 13 (14), 1738-1749, 2012 | 165 | 2012 |
Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants H Zubair, HY Khan, A Sohail, S Azim, MF Ullah, A Ahmad, FH Sarkar, ... Cell death & disease 4 (6), e660-e660, 2013 | 141 | 2013 |
Effect of vitamins C and E on antioxidant status of breast‐cancer patients undergoing chemotherapy N Suhail, N Bilal, HY Khan, S Hasan, S Sharma, F Khan, T Mansoor, ... Journal of clinical pharmacy and therapeutics 37 (1), 22-26, 2012 | 137 | 2012 |
Soy isoflavone genistein induces cell death in breast cancer cells through mobilization of endogenous copper ions and generation of reactive oxygen species MF Ullah, A Ahmad, H Zubair, HY Khan, Z Wang, FH Sarkar, SM Hadi Molecular nutrition & food research 55 (4), 553-559, 2011 | 134 | 2011 |
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer … HY Khan, H Zubair, M Faisal, MF Ullah, M Farhan, FH Sarkar, A Ahmad, ... Molecular nutrition & food research 58 (3), 437-446, 2014 | 116 | 2014 |
Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer SM Hadi, MF Ullah, AS Azmi, A Ahmad, U Shamim, H Zubair, HY Khan Pharmaceutical research 27, 979-988, 2010 | 106 | 2010 |
Cancer therapy by catechins involves redox cycling of copper ions and generation of reactive oxygen species M Farhan, HY Khan, M Oves, A Al-Harrasi, N Rehmani, H Arif, SM Hadi, ... Toxins 8 (2), 37, 2016 | 96 | 2016 |
The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer MF Ullah, HY Khan, H Zubair, U Shamim, SM Hadi Cancer chemotherapy and pharmacology 67, 103-110, 2011 | 83 | 2011 |
Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism HY Khan, H Zubair, MF Ullah, A Ahmad, SM Hadi Biometals 24, 1169-1178, 2011 | 61 | 2011 |
The prooxidant action of dietary antioxidants leading to cellular DNA breakage and anticancer effects: implications for chemotherapeutic action against cancer MF Ullah, A Ahmad, HY Khan, H Zubair, FH Sarkar, SM Hadi Cell biochemistry and biophysics 67, 431-438, 2013 | 53 | 2013 |
Preclinical assessment with clinical validation of selinexor with gemcitabine and nab-paclitaxel for the treatment of pancreatic ductal adenocarcinoma AS Azmi, HY Khan, I Muqbil, A Aboukameel, JE Neggers, D Daelemans, ... Clinical Cancer Research 26 (6), 1338-1348, 2020 | 43 | 2020 |
KRAS G12D targeted therapies for pancreatic cancer: Has the fortress been conquered? SF Bannoura, HY Khan, AS Azmi Frontiers in Oncology 12, 1013902, 2022 | 39 | 2022 |
Mobilization of copper ions in human peripheral lymphocytes by catechins leading to oxidative DNA breakage: A structure activity study M Farhan, A Zafar, S Chibber, HY Khan, H Arif, SM Hadi Archives of biochemistry and biophysics 580, 31-40, 2015 | 39 | 2015 |
Chemistry and bioactivity of boswellic acids and other terpenoids of the genus boswellia A Al-Harrasi, H Hussain, R Csuk, HY Khan Elsevier, 2018 | 37 | 2018 |
Targeting nuclear exporter protein XPO1/CRM1 in gastric cancer R Sexton, Z Mahdi, R Chaudhury, R Beydoun, A Aboukameel, HY Khan, ... International journal of molecular sciences 20 (19), 4826, 2019 | 35 | 2019 |
Calcium release-activated calcium (CRAC) channel inhibition suppresses pancreatic ductal adenocarcinoma cell proliferation and patient-derived tumor growth HY Khan, GB Mpilla, R Sexton, S Viswanadha, KV Penmetsa, ... Cancers 12 (3), 750, 2020 | 33 | 2020 |
Targeting XPO1 and PAK4 in 8505C anaplastic thyroid cancer cells: putative implications for overcoming lenvatinib therapy resistance HY Khan, J Ge, M Nagasaka, A Aboukameel, G Mpilla, I Muqbil, ... International Journal of Molecular Sciences 21 (1), 237, 2019 | 31 | 2019 |
Prooxidant anticancer activity of plant-derived polyphenolic compounds: An underappreciated phenomenon HY Khan, SM Hadi, RM Mohammad, AS Azmi Functional foods in cancer prevention and therapy, 221-236, 2020 | 24 | 2020 |
Selinexor in combination with R-CHOP for frontline treatment of non-hodgkin lymphoma: results of a phase I study EK Seymour, HY Khan, Y Li, M Chaker, I Muqbil, A Aboukameel, ... Clinical Cancer Research 27 (12), 3307-3316, 2021 | 23 | 2021 |
Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage H Zubair, HY Khan, MF Ullah, A Ahmad, D Wu, SM Hadi European journal of pharmaceutical sciences 47 (1), 280-286, 2012 | 23 | 2012 |