IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA M Calfon, H Zeng, F Urano, JH Till, SR Hubbard, HP Harding, SG Clark, ... Nature 415 (6867), 92-96, 2002 | 3283 | 2002 |
C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains SG Clark, MJ Stern, HR Horvritz Nature 356 (6367), 340-344, 1992 | 791 | 1992 |
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones T Yoneda, C Benedetti, F Urano, SG Clark, HP Harding, D Ron Journal of cell science 117 (18), 4055-4066, 2004 | 668 | 2004 |
Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction GJ Beitel, SG Clark, HR Horvitz Nature 348 (6301), 503-509, 1990 | 530 | 1990 |
Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39 SG Clark, AD Chisholm, HR Horvitz Cell 74 (1), 43-55, 1993 | 342 | 1993 |
The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins. SG Clark, X Lu, HR Horvitz Genetics 137 (4), 987-997, 1994 | 301 | 1994 |
Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans BC Prasad, SG Clark Oxford University Press for The Company of Biologists Limited 133 (9), 1757-1766, 2006 | 266 | 2006 |
A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response F Urano, M Calfon, T Yoneda, C Yun, M Kiraly, SG Clark, D Ron The Journal of cell biology 158 (4), 639-646, 2002 | 256 | 2002 |
C. elegans AP-2 and retromer control Wnt signaling by regulating mig-14/Wntless CL Pan, PD Baum, M Gu, EM Jorgensen, SG Clark, G Garriga Developmental cell 14 (1), 132-139, 2008 | 251 | 2008 |
Multiple Wnts and frizzled receptors regulate anteriorly directed cell and growth cone migrations in Caenorhabditis elegans CL Pan, JE Howell, SG Clark, M Hilliard, S Cordes, CI Bargmann, ... Developmental cell 10 (3), 367-377, 2006 | 191 | 2006 |
The Oncogenic Activation of Human p21ras by a Novel Mechanism M Walter, SG Clark, AD Levinson Science 233 (4764), 649-652, 1986 | 191 | 1986 |
C. elegans ZAG-1, a Zn-finger-homeodomain protein, regulates axonal development and neuronal differentiation SG Clark, C Chiu Oxford University Press for The Company of Biologists Limited 130 (16), 3781 …, 2003 | 180 | 2003 |
MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin C Chang, CE Adler, M Krause, SG Clark, FB Gertler, M Tessier-Lavigne, ... Current Biology 16 (9), 854-862, 2006 | 169 | 2006 |
A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans SG Clark, DL Shurland, EM Meyerowitz, CI Bargmann, AM Van Der Bliek Proceedings of the National Academy of Sciences 94 (19), 10438-10443, 1997 | 167 | 1997 |
Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans EJ Cram, SG Clark, JE Schwarzbauer Journal of cell science 116 (19), 3871-3878, 2003 | 137 | 2003 |
Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP kinase D Jacobs, GJ Beitel, SG Clark, HR Horvitz, K Kornfeld Genetics 149 (4), 1809-1822, 1998 | 137 | 1998 |
A mammalian host-vector system that regulates expression and amplification of transfected genes by temperature induction DC Rio, SG Clark, R Tjian Science 227 (4682), 23-28, 1985 | 131 | 1985 |
Axons degenerate in the absence of mitochondria in C. elegans RL Rawson, L Yam, RM Weimer, EG Bend, E Hartwieg, HR Horvitz, ... Current Biology 24 (7), 760-765, 2014 | 96 | 2014 |
The C. elegans gene vab-8 guides posteriorly directed axon outgrowth and cell migration B Wightman, SG Clark, AM Taskar, WC Forrester, AV Maricq, ... Development 122 (2), 671-682, 1996 | 89 | 1996 |
Genetic analysis of the myotubularin family of phosphatases in Caenorhabditis elegans Y Xue, H Fares, B Grant, Z Li, AM Rose, SG Clark, EY Skolnik Journal of Biological Chemistry 278 (36), 34380-34386, 2003 | 79 | 2003 |