ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages CM Cruz, A Rinna, HJ Forman, ALM Ventura, PM Persechini, DM Ojcius Journal of Biological Chemistry 282 (5), 2871-2879, 2007 | 955 | 2007 |
P2Z/P2X7receptor-dependent apoptosis of dendritic cells R Coutinho-Silva, PM Persechini, RDC Bisaggio, JL Perfettini, ... American Journal of Physiology-Cell Physiology 276 (5), C1139-C1147, 1999 | 277 | 1999 |
Structural and functional identification of GP57/51 antigen of Trypanosoma cruzi as a cysteine proteinase ACM Murta, PM Persechini, T de Souto Padron, W de Souza, ... Molecular and biochemical parasitology 43 (1), 27-38, 1990 | 215 | 1990 |
Purified perforin induces target cell lysis but not DNA fragmentation. RC Duke, PM Persechini, S Chang, CC Liu, JJ Cohen, JD Young The Journal of experimental medicine 170 (4), 1451-1456, 1989 | 214 | 1989 |
The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice RG Goncalves, L Gabrich, A Rosario Jr, CM Takiya, MLL Ferreira, ... Kidney international 70 (9), 1599-1606, 2006 | 154 | 2006 |
P2Z purinoceptor-associated pores induced by extracellular ATP in macrophages and J774 cells R Coutinho-Silva, PM Persechini American Journal of Physiology-Cell Physiology 273 (6), C1793-C1800, 1997 | 134 | 1997 |
Perforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by … BCG de Alencar, PM Persechini, FA Haolla, G de Oliveira, JC Silverio, ... Infection and immunity 77 (10), 4383-4395, 2009 | 125 | 2009 |
Distinct Kinetics of Effector CD8+ Cytotoxic T Cells after Infection with Trypanosoma cruzi in Naïve or Vaccinated Mice F Tzelepis, BCG de Alencar, MLO Penido, RT Gazzinelli, PM Persechini, ... Infection and immunity 74 (4), 2477-2481, 2006 | 121 | 2006 |
Modulation of P2Z/P2X7 receptor activity in macrophages infected with Chlamydia psittaci R Coutinho-Silva, JL Perfettini, PM Persechini, A Dautry-Varsat, ... American Journal of Physiology-Cell Physiology 280 (1), C81-C89, 2001 | 119 | 2001 |
Perforin and lymphocyte-mediated cytolysis. CC Liu, PM Persechini, JD Young Immunological reviews 146, 145-175, 1995 | 107 | 1995 |
In vivo expression of perforin by CD8+ lymphocytes in autoimmune disease. Studies on spontaneous and adoptively transferred diabetes in nonobese diabetic mice. LH Young, LB Peterson, LS Wicker, PM Persechini, JD Young Journal of immunology (Baltimore, Md.: 1950) 143 (12), 3994-3999, 1989 | 104 | 1989 |
Perforin-dependent and-independent pathways of cytotoxicity mediated by lymphocytes. JD Young, CC Liu, PM Persechini, ZA Cohn Immunological reviews 103, 161-202, 1988 | 101 | 1988 |
Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages R Coutinho-Silva, DM Ojcius, DC Górecki, PM Persechini, RC Bisaggio, ... Biochemical Pharmacology 69 (4), 641-655, 2005 | 98 | 2005 |
ATP-induced P2X7-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages J Schachter, AP Motta, A de Souza Zamorano, HA da Silva-Souza, ... Journal of cell science 121 (19), 3261-3270, 2008 | 96 | 2008 |
Modulation of P2X7 purinergic receptor in macrophages by Leishmania amazonensis and its role in parasite elimination SP Chaves, EC Torres-Santos, C Marques, VR Figliuolo, PM Persechini, ... Microbes and infection 11 (10-11), 842-849, 2009 | 93 | 2009 |
Are there functional gap junctions or junctional hemichannels in macrophages? LA Alves, R Coutinho-Silva, PM Persechini, DC Spray, W Savino, ... | 87 | 1996 |
Neutrophil extracellular traps release induced by Leishmania: role of PI3Kγ, ERK, PI3Kσ, PKC, and [Ca2+] T DeSouza-Vieira, A Guimarães-Costa, NC Rochael, MN Lira, ... Journal of Leucocyte Biology 100 (4), 801-810, 2016 | 82 | 2016 |
The structure of the mouse lymphocyte pore-forming protein perforin BS Kwon, M Wakulchik, CC Liu, PM Persechini, JA Trapani, AK Haq, ... Biochemical and biophysical research communications 158 (1), 1-10, 1989 | 76 | 1989 |
Modulation of CD4+ T cell-dependent specific cytotoxic CD8+ T cells differentiation and proliferation by the timing of increase in the pathogen load F Tzelepis, PM Persechini, MM Rodrigues PLoS One 2 (4), e393, 2007 | 67 | 2007 |
The role of P2 receptors in controlling infections by intracellular pathogens R Coutinho-Silva, C Monteiro da Cruz, PM Persechini, DM Ojcius Purinergic Signalling 3, 83-90, 2007 | 64 | 2007 |