| Stabilization of a Supersaturated Solution of Mefenamic Acid from a Solid Dispersion with EUDRAGIT® EPO T Kojima, K Higashi, T Suzuki, K Tomono, K Moribe, K Yamamoto Pharmaceutical research 29, 2777-2791, 2012 | 145 | 2012 |
| The effect of HPMCAS functional groups on drug crystallization from the supersaturated state and dissolution improvement K Ueda, K Higashi, K Yamamoto, K Moribe International journal of pharmaceutics 464 (1-2), 205-213, 2014 | 125 | 2014 |
| Inhibitory effect of hydroxypropyl methylcellulose acetate succinate on drug recrystallization from a supersaturated solution assessed using nuclear magnetic resonance measurements K Ueda, K Higashi, K Yamamoto, K Moribe Molecular pharmaceutics 10 (10), 3801-3811, 2013 | 117 | 2013 |
| Recent progress of structural study of polymorphic pharmaceutical drugs K Higashi, K Ueda, K Moribe Advanced drug delivery reviews 117, 71-85, 2017 | 93 | 2017 |
| Effects of the PEG molecular weight of a PEG-lipid and cholesterol on PEG chain flexibility on liposome surfaces K Abe, K Higashi, K Watabe, A Kobayashi, W Limwikrant, K Yamamoto, ... Colloids and surfaces A: physicochemical and engineering aspects 474, 63-70, 2015 | 83 | 2015 |
| Self‐degradable lipid‐like materials based on “hydrolysis accelerated by the intra‐particle enrichment of reactant (HyPER)” for messenger RNA delivery H Tanaka, T Takahashi, M Konishi, N Takata, M Gomi, D Shirane, ... Advanced Functional Materials 30 (34), 1910575, 2020 | 80 | 2020 |
| A novel drug-drug cocrystal of levofloxacin and metacetamol: Reduced hygroscopicity and improved photostability of levofloxacin T Shinozaki, M Ono, K Higashi, K Moribe Journal of Pharmaceutical Sciences 108 (7), 2383-2390, 2019 | 77 | 2019 |
| Characterization and evaluation of miconazole salts and cocrystals for improved physicochemical properties S Tsutsumi, M Iida, N Tada, T Kojima, Y Ikeda, T Moriwaki, K Higashi, ... International journal of pharmaceutics 421 (2), 230-236, 2011 | 77 | 2011 |
| Physicochemical characterization and structural evaluation of a specific 2: 1 cocrystal of naproxen–nicotinamide S Ando, J Kikuchi, Y Fujimura, Y Ida, K Higashi, K Moribe, K Yamamoto Journal of pharmaceutical sciences 101 (9), 3214-3221, 2012 | 74 | 2012 |
| Mechanistic differences in permeation behavior of supersaturated and solubilized solutions of carbamazepine revealed by nuclear magnetic resonance measurements K Ueda, K Higashi, W Limwikrant, S Sekine, T Horie, K Yamamoto, ... Molecular pharmaceutics 9 (11), 3023-3033, 2012 | 73 | 2012 |
| Insights into atomic-level interaction between mefenamic acid and Eudragit EPO in a supersaturated solution by high-resolution magic-angle spinning NMR spectroscopy K Higashi, K Yamamoto, MK Pandey, KH Mroue, K Moribe, K Yamamoto, ... Molecular pharmaceutics 11 (1), 351-357, 2014 | 60 | 2014 |
| The effect of drug and EUDRAGIT® S 100 miscibility in solid dispersions on the drug and polymer dissolution rate K Higashi, H Hayashi, K Yamamoto, K Moribe International Journal of Pharmaceutics 494 (1), 9-16, 2015 | 59 | 2015 |
| Molecular interaction among probucol/PVP/SDS multicomponent system investigated by solid-state NMR A Pongpeerapat, K Higashi, Y Tozuka, K Moribe, K Yamamoto Pharmaceutical research 23, 2566-2574, 2006 | 58 | 2006 |
| Drug nanoparticle formulation using ascorbic acid derivatives K Moribe, W Limwikrant, K Higashi, K Yamamoto Journal of drug delivery 2011 (1), 138929, 2011 | 55 | 2011 |
| Synergetic role of hypromellose and methacrylic acid copolymer in the dissolution improvement of amorphous solid dispersions N Ohyagi, K Ueda, K Higashi, K Yamamoto, K Kawakami, K Moribe Journal of Pharmaceutical Sciences 106 (4), 1042-1050, 2017 | 52 | 2017 |
| Salicylic acid/γ-cydodextrin 2: 1 and 4: 1 complex formation by sealed-heating method K Higashi, Y Tozuka, K Moribe, K Yamamoto Journal of pharmaceutical sciences 99 (10), 4192-4200, 2010 | 51 | 2010 |
| Incorporation of salicylic acid molecules into the intermolecular spaces of γ-cyclodextrin-polypseudorotaxane K Higashi, S Ideura, H Waraya, K Moribe, K Yamamoto Crystal growth & design 9 (10), 4243-4246, 2009 | 50 | 2009 |
| Direct evaluation of molecular states of piroxicam/poloxamer nanosuspension by suspended-state NMR and Raman spectroscopies Y Hasegawa, K Higashi, K Yamamoto, K Moribe Molecular pharmaceutics 12 (5), 1564-1572, 2015 | 46 | 2015 |
| Formation mechanism of a new carbamazepine/malonic acid cocrystal polymorph W Limwikrant, A Nagai, Y Hagiwara, K Higashi, K Yamamoto, K Moribe International Journal of Pharmaceutics 431 (1-2), 237-240, 2012 | 46 | 2012 |
| Nano-scale and molecular-level understanding of wet-milled indomethacin/poloxamer 407 nanosuspension with TEM, suspended-state NMR, and Raman measurements Y Kuroiwa, K Higashi, K Ueda, K Yamamoto, K Moribe International Journal of Pharmaceutics 537 (1-2), 30-39, 2018 | 44 | 2018 |
