ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules D Mukhi, L Li, H Liu, T Doke, LP Kolligundla, E Ha, K Kloetzer, A Abedini, ... The Journal of Clinical Investigation 134 (4), 2024 | 4 | 2024 |
Aging-associated renal disease in mice is fructokinase dependent CA Roncal-Jimenez, T Ishimoto, MA Lanaspa, T Milagres, AA Hernando, ... American Journal of Physiology-Renal Physiology 311 (4), F722-F730, 2016 | 36 | 2016 |
Aging-associated Renal Disease in Mice is Fructokinase Dependent A Hernando, T Jensen, M Miyazaki, T Doke, T Hayasaki, ... | | 2016 |
COMBINATION OF HIGH FRUCTOSE AND HIGH SALT AFFECTS SODIUM ABSORPTION AND INDUCE THE ELEVATION OF BLOOD PRESSURE THAT IS DEPENDENT ON KETOHEXOKINASE T Hayasaki, T Ishimoto, T Doke, T Kosugi, RJ Johnson, K Kadomatsu, ... NEPHROLOGY DIALYSIS TRANSPLANTATION 31, 110-110, 2016 | | 2016 |
Comprehensive dipeptide profiling and quantitation by capillary electrophoresis and liquid chromatography coupled with tandem mass spectrometry H Ozawa, A Hirayama, T Ishikawa, R Kudo, M Maruyama, F Shoji, T Doke, ... Analytical Chemistry 92 (14), 9799-9806, 2020 | 21 | 2020 |
DACH1 protects podocytes from experimental diabetic injury and modulates PTIP-H3K4Me3 activity A Cao, J Li, M Asadi, JM Basgen, B Zhu, Z Yi, S Jiang, T Doke, ... The Journal of clinical investigation 131 (10), 2021 | 26 | 2021 |
DAINI TOYOKAIJI BUILDING 24-8, SHINBASHI 4 CHOME, MINATO-KU TOKYO 105 JAPAN H Kumagai, G Tominaga, Y Tuzi, H Suzuki, Y Sato, S Ogawa, S Hyodo, ... JJAP 15, 199, 1976 | | 1976 |
Endothelial–Mesenchymal Transition Switch and Diabetic Kidney Disease T Doke, P Bjornstad Journal of the American Society of Nephrology, 10.1681, 2024 | | 2024 |
Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease H Liu, T Doke, D Guo, X Sheng, Z Ma, J Park, HMT Vy, GN Nadkarni, ... Nature genetics 54 (7), 950-962, 2022 | 74 | 2022 |
Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase T Hayasaki, T Ishimoto, T Doke, A Hirayama, T Soga, K Furuhashi, N Kato, ... The Journal of Nutritional Biochemistry 71, 54-62, 2019 | 16 | 2019 |
FRUCTOSE METABOLISM INCREASES BLOOD PRESSURE BY THE UPREGULATION OF RENAL SODIUM REABSORPTION IN MICE T Hayasaki, T Ishimoto, T Doke, M Lanaspa, R Johnson, S Maruyama NEPHROLOGY DIALYSIS TRANSPLANTATION 33, 2018 | | 2018 |
Genome-wide association studies identify the role of caspase-9 in kidney disease T Doke, S Huang, C Qiu, X Sheng, M Seasock, H Liu, Z Ma, M Palmer, ... Science advances 7 (45), eabi8051, 2021 | 15 | 2021 |
Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice T Doke, T Ishimoto, T Hayasaki, S Ikeda, M Hasebe, A Hirayama, T Soga, ... Metabolism 85, 161-170, 2018 | 21 | 2018 |
LACKING OF KETOHEXOKINASE AMELIORATED THE RENAL LIPID ACCUMULATION IN HIGH-FAT DIET FED STREPTOZOTOCIN INDUCED DIABETIC MICE T Doke, T Ishimoto, T Hayasaki, R Johnson, S Maruyama NEPHROLOGY DIALYSIS TRANSPLANTATION 33, 2018 | | 2018 |
Long non-coding RNA lnc-CHAF1B-3 promotes renal interstitial fibrosis by regulating EMT-related genes in renal proximal tubular cells K Imai, T Ishimoto, T Doke, T Tsuboi, Y Watanabe, K Katsushima, ... Molecular Therapy-Nucleic Acids 31, 139-150, 2023 | 7 | 2023 |
Molecular pathways that drive diabetic kidney disease S Mohandes, T Doke, H Hu, D Mukhi, P Dhillon, K Susztak The Journal of clinical investigation 133 (4), 2023 | 79 | 2023 |
MP063 AGING-ASSOCIATED RENAL DISEASE IN MICE IS DEPENDENT ON FRUCTOKINASE T Ishimoto, C Roncal-Jimenez, M Lanaspa, T Milagres, A Hernando, ... Nephrology Dialysis Transplantation 32 (suppl_3), iii448-iii449, 2017 | | 2017 |
NAD+ flux is maintained in aged mice despite lower tissue concentrations MR McReynolds, K Chellappa, E Chiles, C Jankowski, Y Shen, L Chen, ... Cell systems 12 (12), 1160-1172. e4, 2021 | 58 | 2021 |
NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury T Doke, S Mukherjee, D Mukhi, P Dhillon, A Abedini, JG Davis, ... Nature metabolism 5 (3), 414-430, 2023 | 28 | 2023 |
Post-transplant membranous nephropathy associated with chronic active antibody-mediated rejection and Hepatitis C infection after deceased donor renal transplantation T Doke, W Sato, K Takahashi, H Hayashi, S Koide, H Sasaki, M Kusaka, ... Internal Medicine 55 (4), 375-380, 2016 | 4 | 2016 |