A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress O Brandman, J Stewart-Ornstein, D Wong, A Larson, CC Williams, GW Li, ... Cell 151 (5), 1042-1054, 2012 | 655 | 2012 |
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome DK Breslow, DM Cameron, SR Collins, M Schuldiner, J Stewart-Ornstein, ... Nature methods 5 (8), 711-718, 2008 | 631 | 2008 |
In silico feedback for in vivo regulation of a gene expression circuit A Milias-Argeitis, S Summers, J Stewart-Ornstein, I Zuleta, D Pincus, ... Nature biotechnology 29 (12), 1114-1116, 2011 | 331 | 2011 |
Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae J Stewart-Ornstein, JS Weissman, H El-Samad Molecular cell 45 (4), 483-493, 2012 | 187 | 2012 |
Fluctuations in p53 signaling allow escape from cell-cycle arrest J Reyes, JY Chen, J Stewart-Ornstein, KW Karhohs, CS Mock, G Lahav Molecular cell 71 (4), 581-591. e5, 2018 | 126 | 2018 |
p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics A Hafner, J Stewart-Ornstein, JE Purvis, WC Forrester, ML Bulyk, G Lahav Nature structural & molecular biology 24 (10), 840-847, 2017 | 102 | 2017 |
Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins J Stewart-Ornstein, AP Hitchcock, D Hernández Cruz, P Henklein, ... The Journal of Physical Chemistry B 111 (26), 7691-7699, 2007 | 102 | 2007 |
p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM J Stewart-Ornstein, G Lahav Science signaling 10 (476), eaah6671, 2017 | 95 | 2017 |
Dynamics of CDKN1A in single cells defined by an endogenous fluorescent tagging toolkit J Stewart-Ornstein, G Lahav Cell reports 14 (7), 1800-1811, 2016 | 92 | 2016 |
In situ spatial and time-resolved studies of electrochemical reactions by scanning transmission X-ray microscopy D Guay, J Stewart-Ornstein, X Zhang, AP Hitchcock Analytical chemistry 77 (11), 3479-3487, 2005 | 74 | 2005 |
Msn2 coordinates a stoichiometric gene expression program J Stewart-Ornstein, C Nelson, J DeRisi, JS Weissman, H El-Samad Current Biology 23 (23), 2336-2345, 2013 | 60 | 2013 |
Conservation and divergence of p53 oscillation dynamics across species J Stewart-Ornstein, HWJ Cheng, G Lahav Cell systems 5 (4), 410-417. e4, 2017 | 57 | 2017 |
Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening RP Barnes, M de Rosa, SA Thosar, AC Detwiler, V Roginskaya, ... Nature structural & molecular biology 29 (7), 639-652, 2022 | 54 | 2022 |
p53 dynamics vary between tissues and are linked with radiation sensitivity J Stewart-Ornstein, Y Iwamoto, MA Miller, MA Prytyskach, S Ferretti, ... Nature Communications 12 (1), 898, 2021 | 50 | 2021 |
Optogenetic control reveals differential promoter interpretation of transcription factor nuclear translocation dynamics SY Chen, LC Osimiri, M Chevalier, LJ Bugaj, TH Nguyen, RA Greenstein, ... Cell systems 11 (4), 336-353. e24, 2020 | 50 | 2020 |
The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy AE Granada, A Jiménez, J Stewart-Ornstein, N Blüthgen, S Reber, ... Molecular biology of the cell 31 (8), 845-857, 2020 | 39 | 2020 |
Quantifying the central dogma in the p53 pathway in live single cells A Hafner, J Reyes, J Stewart-Ornstein, M Tsabar, A Jambhekar, G Lahav Cell systems 10 (6), 495-505. e4, 2020 | 37 | 2020 |
Model-guided optogenetic study of PKA signaling in budding yeast J Stewart-Ornstein, S Chen, R Bhatnagar, JS Weissman, H El-Samad Molecular Biology of the cell 28 (1), 221-227, 2017 | 31 | 2017 |
Building robust functionality in synthetic circuits using engineered feedback regulation S Chen, P Harrigan, B Heineike, J Stewart-Ornstein, H El-Samad Current opinion in biotechnology 24 (4), 790-796, 2013 | 31 | 2013 |
RNA-seq reveals novel mechanistic targets of withaferin A in prostate cancer cells SH Kim, ER Hahm, KB Singh, S Shiva, J Stewart-Ornstein, SV Singh Carcinogenesis 41 (6), 778-789, 2020 | 23 | 2020 |