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Teepu Siddique
Teepu Siddique
Northwestern University Feinberg School of Medicine
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
DR Rosen, T Siddique, D Patterson, DA Figlewicz, P Sapp, A Hentati, ...
Nature 362 (6415), 59-62, 1993
87661993
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
ME Gurney, H Pu, AY Chiu, MC Dal Canto, CY Polchow, DD Alexander, ...
Science 264 (5166), 1772-1775, 1994
48561994
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
TJ Kwiatkowski Jr, DA Bosco, AL Leclerc, E Tamrazian, CR Vanderburg, ...
Science 323 (5918), 1205-1208, 2009
30562009
Amyotrophic lateral Ssclerosis and structural defects in cu, Zn superoxide dismutase
HX Deng, A Hentati, JA Tainer, Z Iqbal, A Cayabyab, WY Hung, ...
Science 261 (5124), 1047-1051, 1993
18871993
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
HX Deng, W Chen, ST Hong, KM Boycott, GH Gorrie, N Siddique, Y Yang, ...
Nature 477 (7363), 211-215, 2011
13902011
Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
IRA Mackenzie, EH Bigio, PG Ince, F Geser, M Neumann, NJ Cairns, ...
Annals of Neurology: Official Journal of the American Neurological …, 2007
11792007
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
YI Yang, A Hentati, HX Deng, O Dabbagh, T Sasaki, M Hirano, WY Hung, ...
Nature genetics 29 (2), 160-165, 2001
9462001
Understanding transgenerational epigenetic inheritance via the gametes in mammals
L Daxinger, E Whitelaw
Nature Reviews Genetics 13 (3), 153-162, 2012
8292012
SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis
F Fecto, J Yan, SP Vemula, E Liu, Y Yang, W Chen, JG Zheng, Y Shi, ...
Archives of neurology 68 (11), 1440-1446, 2011
7702011
The structural biochemistry of the superoxide dismutases
JJP Perry, DS Shin, ED Getzoff, JA Tainer
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (2), 245-262, 2010
6582010
Presence of dendritic cells, MCP‐1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
JS Henkel, JI Engelhardt, L Siklós, EP Simpson, SH Kim, T Pan, ...
Annals of Neurology: Official Journal of the American Neurological …, 2004
6332004
Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity
T Siddique, DA Figlewigz, MA Pericak-Vance, JL Haines, G Rouleau, ...
New England Journal of Medicine 324 (20), 1381-1384, 1991
5331991
Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria
HX Deng, Y Shi, Y Furukawa, H Zhai, R Fu, E Liu, GH Gorrie, MS Khan, ...
Proceedings of the National Academy of Sciences 103 (18), 7142-7147, 2006
5322006
Familial amyotrophic lateral sclerosis with frontotemporal dementia is linked to a locus on chromosome 9p13. 2–21.3
C Vance, A Al-Chalabi, D Ruddy, BN Smith, X Hu, J Sreedharan, ...
Brain 129 (4), 868-876, 2006
4972006
Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22
BA Hosler, T Siddique, PC Sapp, W Sailor, MC Huang, A Hossain, ...
Jama 284 (13), 1664-1669, 2000
4602000
A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease
AD Roses, MW Lutz, H Amrine-Madsen, AM Saunders, DG Crenshaw, ...
The pharmacogenomics journal 10 (5), 375-384, 2010
4562010
A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease
MK Lee, JR Marszalek, DW Cleveland
Neuron 13 (4), 975-988, 1994
4361994
FUS‐immunoreactive inclusions are a common feature in sporadic and non‐SOD1 familial amyotrophic lateral sclerosis
HX Deng, H Zhai, EH Bigio, J Yan, F Fecto, K Ajroud, M Mishra, ...
Annals of neurology 67 (6), 739-748, 2010
4352010
Textbook of clinical neurology
CG Goetz
Elsevier Health Sciences, 2007
4152007
A double‐blind placebo‐controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis
ALS CNTF Treatment Study Group
Neurology 46 (5), 1244-1244, 1996
3741996
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